Publications by authors named "Stephen Meltzer"

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A machine-learning informed circulating microbial DNA signature for early diagnosis of esophageal adenocarcinoma.
Yuan Li, Caiming Xu, Hyun Park, Ashten N Omstead, Muhammad Anees, Stephen J Meltzer

Gut Microbes· December 2026

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Discovery of Methylated DNA Biomarkers for Potential Nonendoscopic Detection of Barrett's Esophagus and Esophageal Adenocarcinoma.
Andrew Kalra, Ke Ma, Yulan Cheng, Hua-Ling Tsai, Hao Wang, Stephen J Meltzer

Am J Gastroenterol· October 2025

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Chromosome 20q gene signature associated with colorectal cancer progression.
Jennifer Carter Jones, Apurva M Hegde, Yu-Jing Huang, Ganiraju Manyam, Vibhuti Srivastava, Stephen J Meltzer

Oncol Rep· October 2025

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Delivery of cancer cell-derived extracellular vesicles modulates the morphology and gene expression of Barrett esophagus and duodenal organoids (Article).
Rong Yan, Xiquan Ke, Yulan Cheng, Xi Liu, Zhixiong Wang, Stephen J Meltzer

Biochem Biophys Res Commun· July 2025

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The Role of DNA Methylation in Gastrointestinal Disease: An Expanded Review of Malignant and Nonmalignant Gastrointestinal Diseases.
Andrew Kalra, Stephen J Meltzer

Gastroenterology· February 2025

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Neoplastic Progression Risk in Females With Barrett's Esophagus: A Systematic Review and Meta-Analysis of Individual Patient Data.
Pauline A Zellenrath, Laurelle van Tilburg, Roos E Pouw, Rena Yadlapati, Yonne Peters, Stephen J Meltzer

Clin Gastroenterol Hepatol· February 2025

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Spatiotemporal Study of a Risk-Stratification Epigenetic-Based Biomarker Assay in Patients With Barrett Esophagus.
Sarah E Laun, Lisa Kann, Jerome Braun, Francia Pierre, Suji Kim, Stephen J Meltzer

Am J Gastroenterol· February 2025

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Liquid biopsy to identify Barrett's oesophagus, dysplasia and oesophageal adenocarcinoma: the multicentre study.
Jinsei Miyoshi, Alessandro Mannucci, Marco Scarpa, Feng Gao, Shusuke Toden, Stephen J Meltzer

Gut· January 2025

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Analytical Validation of Esopredict, an Epigenetic Prognostic Assay for Patients with Barrett's Esophagus.
Sarah Laun, Francia Pierre, Suji Kim, Daniel Lunz, Tara Maddala, Stephen J Meltzer

Diagnostics (Basel)· September 2024

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Validation of an Epigenetic Prognostic Assay to Accurately Risk-Stratify Patients With Barrett Esophagus.
Sarah E Laun, Lisa Kann, Jerome Braun, Stacey Gilbert, Daniel Lunz, Stephen J Meltzer

Am J Gastroenterol· August 2024

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Cancer Methylation Biomarker Detection in an Automated, Portable, Multichannel Magnetofluidic Platform.
Alexander C Hasnain, Alejandro Stark, Alexander Y Trick, Ke Ma, Kuangwen Hsieh, Stephen J Meltzer

ACS Nano· May 2024

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Establishing mouse and human oral esophageal organoids to investigate the tumor immune response.
Yuan Jiang, Hua Zhao, Shuai Kong, Dan Zhou, Jinxiu Dong, Stephen J Meltzer

Dis Model Mech· January 2024

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PAD4-dependent citrullination of nuclear translocation of GSK3β promotes colorectal cancer progression via the degradation of nuclear CDKN1A.
Xiaonuan Luo, Shanshan Chang, Siyu Xiao, Yin Peng, Yuli Gao, Stephen J Meltzer

Neoplasia· November 2022

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Generation and multiomic profiling of a double-knockout gastroesophageal junction organoid model.
Hua Zhao, Yulan Cheng, Andrew Kalra, Ke Ma, Yueyuan Zheng, Stephen J Meltzer

Sci Transl Med· November 2022

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Vimentin binds to a novel tumor suppressor protein, GSPT1-238aa, encoded by circGSPT1 with a selective encoding priority to halt autophagy in gastric carcinoma.
Fan Hu, Yin Peng, Shanshan Chang, Xiaonuan Luo, Yuan Yuan, Stephen J Meltzer

Cancer Lett· October 2022

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The utility of a genetic progression risk test for Barrett esophagus.
Dennis Gong, Daniel Lunz, James S Stover, Stephen J Meltzer

Medicine (Baltimore)· September 2022

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Accurate Nonendoscopic Detection of Esophageal Squamous Cell Carcinoma Using Methylated DNA Biomarkers.
Ke Ma, Andrew Kalra, Hua-Ling Tsai, Samson Okello, Yulan Cheng, Stephen J Meltzer

Gastroenterology· August 2022

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A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression.
Yin Peng, Yidan Xu, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Stephen J Meltzer

Mol Cancer· December 2021

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EpiPanGI Dx: A Cell-free DNA Methylation Fingerprint for the Early Detection of Gastrointestinal Cancers.
Raju Kandimalla, Jianfeng Xu, Alexander Link, Takatoshi Matsuyama, Kensuke Yamamura, Stephen J Meltzer

Clin Cancer Res· November 2021

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Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.
Li-Yan Li, Qian Yang, Yan-Yi Jiang, Wei Yang, Yuan Jiang, Stephen J Meltzer

Nat Commun· July 2021

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microRNA-196b promotes esophageal squamous cell carcinogenesis and chemoradioresistance by inhibiting EPHA7, thereby restoring EPHA2 activity.
Xiaohui Tan, Shuchang Ren, Melinda Z Fu, Shuyang Ren, Canyuan Yang, Stephen J Meltzer

Am J Cancer Res· July 2021

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Protein synthesis inhibitor omacetaxine is effective against hepatocellular carcinoma.
Ling Li, Gilad Halpert, Michael G Lerner, Haijie Hu, Peter Dimitrion, Stephen J Meltzer

JCI Insight· June 2021

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Dual activation of Hedgehog and Wnt/β-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer.
Yin Peng, Xiaojing Zhang, Huijuan Lin, Shiqi Deng, Ying Qin, Stephen J Meltzer

Aging (Albany NY)· April 2021

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MiRNA-20b/SUFU/Wnt axis accelerates gastric cancer cell proliferation, migration and EMT.
Yin Peng, Ying Qin, Xiaojing Zhang, Shiqi Deng, Yuan Yuan, Stephen J Meltzer

Heliyon· April 2021

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Novel Long Noncoding RNA miR205HG Functions as an Esophageal Tumor-Suppressive Hedgehog Inhibitor.
Jee Hoon Song, Alan H Tieu, Yulan Cheng, Ke Ma, Venkata S Akshintala, Stephen J Meltzer

Cancers (Basel)· April 2021

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