Publications by authors named "Stephen Ralph"

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Unifying and accelerating level-set and density-based topology optimization by subpixel-smoothed projection.
Alec M Hammond, Ardavan Oskooi, Ian M Hammond, Mo Chen, Stephen E Ralph

Opt Express· August 2025

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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes.
Nicholas Kusi-Appauh, Stefan H Mueller, Stephen F Ralph, Olga Yurieva, Michael E O'Donnell

J Vis Exp· April 2025

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Fabrication tolerant multi-layer integrated photonic topology optimization.
Michael J Probst, Arjun Khurana, Joel B Slaby, Alec M Hammond, Stephen E Ralph

Opt Express· August 2024

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Effect of substituents on the ability of nickel Schiff base complexes with four pendant groups to bind to G-quadruplexes.
Nawal Assadawi, Myles Ferderer, Nicholas Kusi-Appauh, Haibo Yu, Carolyn T Dillon, Stephen F Ralph

Dalton Trans· July 2024

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Therapeutic Targeting of Mitochondrial Plasticity and Redox Control to Overcome Cancer Chemoresistance.
Shalini Mani, Stephen J Ralph, Geeta Swargiary, Madhu Rani, Samiksha Wasnik

Antioxid Redox Signal· September 2023

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G-quadruplex DNA binding properties of novel nickel Schiff base complexes with four pendant groups.
Nawal Assadawi, Christopher Richardson, Stephen F Ralph

Dalton Trans· September 2023

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Understanding G-Quadruplex Biology and Stability Using Single-Molecule Techniques.
Nicholas Kusi-Appauh, Stephen F Ralph, Antoine M van Oijen, Lisanne M Spenkelink

J Phys Chem B· June 2023

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Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer.
Frank J Echtenkamp, Ryo Ishida, Genesis M Rivera-Marquez, Marisa Maisiak, Oleta T Johnson, Stephen John Ralph

PNAS Nexus· April 2023

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Intratumoral pro-oxidants promote cancer immunotherapy by recruiting and reprogramming neutrophils to eliminate tumors.
Stephen John Ralph, Maxwell J Reynolds

Cancer Immunol Immunother· March 2023

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Multi-layer inverse design of vertical grating couplers for high-density, commercial foundry interconnects.
Alec M Hammond, Joel B Slaby, Michael J Probst, Stephen E Ralph

Opt Express· August 2022

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Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy.
Shalini Mani, Geeta Swargiary, Stephen J Ralph

Mitochondrion· January 2022

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Constellation-based identification of linear and nonlinear OSNR using machine learning: a study of link-agnostic performance.
Hyung Joon Cho, Daniel Lippiatt, Varghese A Thomas, Siddharth Varughese, Steven Searcy, Stephen E Ralph

Opt Express· January 2022

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High-performance hybrid time/frequency-domain topology optimization for large-scale photonics inverse design.
Alec M Hammond, Ardavan Oskooi, Mo Chen, Zin Lin, Steven G Johnson, Stephen E Ralph

Opt Express· January 2022

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Tea tree oil extract causes mitochondrial superoxide production and apoptosis as an anticancer agent, promoting tumor infiltrating neutrophils cytotoxic for breast cancer to induce tumor regression.
Amanda M Clark, Chandi Magawa, Adriana Pliego-Zamora, Pauline Low, Max Reynolds, Stephen J Ralph

Biomed Pharmacother· August 2021

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Photonic topology optimization with semiconductor-foundry design-rule constraints.
Alec M Hammond, Ardavan Oskooi, Steven G Johnson, Stephen E Ralph

Opt Express· July 2021

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Non-Steroidal Anti-Inflammatory Drugs Increase Cisplatin, Paclitaxel, and Doxorubicin Efficacy against Human Cervix Cancer Cells.
Diana Xochiquetzal Robledo-Cadena, Juan Carlos Gallardo-Pérez, Víctor Dávila-Borja, Silvia Cecilia Pacheco-Velázquez, Javier Alejandro Belmont-Díaz, Stephen John Ralph

Pharmaceuticals (Basel)· December 2020

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Optical performance monitoring using digital coherent receivers and convolutional neural networks.
Hyung Joon Cho, Siddharth Varughese, Daniel Lippiatt, Richard Desalvo, Sorin Tibuleac, Stephen E Ralph

Opt Express· October 2020

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The effect of isomerism and other structural variations on the G-quadruplex DNA-binding properties of some nickel Schiff base complexes.
Son Q T Pham, Christopher Richardson, Celine Kelso, Anthony C Willis, Stephen F Ralph

Dalton Trans· August 2020

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A study of Pt(II)-phenanthroline complex interactions with double-stranded and G-quadruplex DNA by ESI-MS, circular dichroism, and computational docking.
Dale L Ang, Celine Kelso, Jennifer L Beck, Stephen F Ralph, David G Harman

J Biol Inorg Chem· May 2020

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A new class of quadruplex DNA-binding nickel Schiff base complexes.
Son Q T Pham, Nawal Assadawi, Jadon Wells, Reece A Sophocleous, Kimberley J Davis, Stephen F Ralph

Dalton Trans· April 2020

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Phase I/II parallel double-blind randomized controlled clinical trial of perispinal etanercept for chronic stroke: improved mobility and pain alleviation.
Stephen J Ralph, Andrew Weissenberger, Ventzislav Bonev, Liam D King, Mikaela D Bonham

Expert Opin Investig Drugs· March 2020

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Repurposing drugs as pro-oxidant redox modifiers to eliminate cancer stem cells and improve the treatment of advanced stage cancers.
Stephen J Ralph, Sam Nozuhur, Reem Ali ALHulais, Sara Rodríguez-Enríquez, Rafael Moreno-Sánchez

Med Res Rev· November 2019

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Three-dimensional bottom diffraction in the North Pacific.
Ralph A Stephen, S Thompson Bolmer, Peter F Worcester, Matthew A Dzieciuch, Ilya A Udovydchenkov

J Acoust Soc Am· September 2019

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Effect of structure variations on the quadruplex DNA binding ability of nickel Schiff base complexes.
Kimberley J Davis, Nawal M O Assadawi, Son Q T Pham, Monica L Birrento, Christopher Richardson, Stephen F Ralph

Dalton Trans· October 2018

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Increased All-Cause Mortality by Antipsychotic Drugs: Updated Review and Meta-Analysis in Dementia and General Mental Health Care.
Stephen J Ralph, Anthony J Espinet

J Alzheimers Dis Rep· February 2018

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