Publications by authors named "Suresh Rayala"

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Expression of Transmembrane Glycoprotein TROP2 in Triple-Negative Breast Cancer and It's Potential as a Molecular Classifier for Targeted Therapy.
Roshni Saravanan, Vaishnavi Balasubramanian, Srikanth Swamy Swaroop B, Jagadeesh Kumar Naidu, Nivetha Balasubramanian, Suresh Kumar Rayala

Cancer Invest· December 2025

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Sugars to signals: emerging roles of PAK1 in Re-wiring glucose metabolism in cancers.
Prarthana Gopinath, Srikanth Swamy Swaroop B, Ganesh Venkatraman, Suresh Kumar Rayala

Expert Opin Ther Targets· December 2025

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Spatio-temporal localization of P21-activated kinase in endometrial cancer.
Joydeep Roy, Nagarajan Hemavathy, Roshni Saravanan, Prarthana Gopinath, Pooja Pugazh, Suresh Kumar Rayala

Biotechnol Appl Biochem· June 2025

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P21-Activated Kinase 1 (PAK1) Modulates Therapeutic Response to Ionizing Radiation in Head and Neck Squamous Cell Carcinoma Cells.
Swetha Rajendran, Rohan Prasad Surabhi, A Satheesh Kumar, Prarthana Gopinath, Vishnupriya Kanakaveti, Suresh Kumar Rayala

Mol Carcinog· June 2025

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Birefringent characterization of nerve tissue and tendon using low coherence interferometry and transmission studies.
Richa Parihar, Nilesh J Vasa, Joy Mammen, Suresh Kumar Rayala

Appl Opt· June 2025

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Transcriptome Analysis of Human Pancreatic Stellate Cells Co-cultured With PAK1-Modulated Cells Revealed the Role of Cytokine Pathway in Tumor Microenvironment.
Sridevi Duggirala, Vaishnavi Balasubramanian, Abirami Seetharaman, Sowmiya Murugan, Joydeep Roy, Suresh Kumar Rayala

Pancreas· May 2025

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Novel Combination Therapy Targeting Oncogenic Signaling Kinase P21-Activated Kinase 1 and Chemotherapeutic Drugs Against Triple-Negative Breast Cancer.
Inemai Ezhil, Abirami Seetharaman, Rahul Kanumuri, Barathidasan Rajamani, Ranga Rao Gangavarapu, Suresh K Rayala

Mol Cancer Ther· April 2025

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Pak1 dysregulates pyruvate metabolism in PDAC cells by exerting a phosphorylation-mediated regulatory effect on PDHA1.
Sowmiya Murugan, Srikanth Swamy Swaroop B, Prarthana Gopinath, Roshni Saravanan, Sandhya Sundaram, Suresh Kumar Rayala

J Biol Chem· April 2025

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Genetic alteration of mRNA editing enzyme APOBEC3B in the pathogenesis of ovarian endometriosis.
Vaishnavi Balasubramanian, Roshni Saravanan, Srikanth Swamy Swaroop Balamurugan, Swetha Rajendran, Leena Dennis Joseph, Suresh Kumar Rayala

Reprod Biomed Online· November 2024

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Next-generation biomarkers for prognostic and potential therapeutic enhancement in Triple negative breast cancer.
Risav Banerjee, Indrajit Maitra, Trisha Bhattacharya, Manosi Banerjee, Gnanasambandan Ramanathan, Suresh Kumar Rayala

Crit Rev Oncol Hematol· September 2024

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Expression of cell surface zinc transporter LIV1 in triple negative breast cancer is an indicator of poor prognosis and therapy failure.
Roshni Saravanan, Vaishnavi Balasubramanian, Sandhya Sundaram, Bhawna Dev, Pavithra Vittalraj, Suresh Kumar Rayala

J Cell Physiol· April 2024

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Anti-cancer Application of Nat-ZnFeO Nanoparticles on 2D Tumor Models.
Siva Chander Chabattula, Bamadeb Patra, Piyush Kumar Gupta, Kavitha Govarthanan, Suresh Kumar Rayala

Appl Biochem Biotechnol· February 2024

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Anti-cancer Activity of Biogenic Nat-ZnO Nanoparticles Synthesized Using Nyctanthes arbor-tristis (Nat) Flower Extract.
Siva Chander Chabattula, Piyush Kumar Gupta, Kavitha Govarthanan, Sudha Varadaraj, Suresh Kumar Rayala

Appl Biochem Biotechnol· January 2024

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Zinc transporter LIV1: A promising cell surface target for triple negative breast cancer.
Roshni Saravanan, Vaishnavi Balasubramanian, Srikanth Swamy Swaroop Balamurugan, Inemai Ezhil, Zeba Afnaan, Suresh Kumar Rayala

J Cell Physiol· November 2022

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Novel BH4-BCL-2 Domain Antagonists Induce BCL-2-Mediated Apoptosis in Triple-Negative Breast Cancer.
Vishnupriya Kanakaveti, Sakthivel Ramasamy, Rahul Kanumuri, Vaishnavi Balasubramanian, Roshni Saravanan, Suresh Kumar Rayala

Cancers (Basel)· October 2022

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Water Mapping and Scoring Approaches to Predict the Role of Hydration Sites in the Binding Affinity of PAK1 Inhibitors.
Jayashree Biswal, Prajisha Jayaprakash, Suresh Kumar Rayala, Ganesh Venkatraman, Raghu Rangasamy

Comb Chem High Throughput Screen· March 2022

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Inflammation-induced PELP1 expression promotes tumorigenesis by activating GM-CSF paracrine secretion in the tumor microenvironment.
Veena Kumari Vuttaradhi, Inemai Ezhil, Divya Ramani, Rahul Kanumuri, Swetha Raghavan, Suresh Kumar Rayala

J Biol Chem· January 2022

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p21 activated kinase-1 and tamoxifen - A deadly nexus impacting breast cancer outcomes.
Swetha Rajendran, Srikanth Swamy Swaroop, Joydeep Roy, Ezhil Inemai, Sowmiya Murugan, Suresh K Rayala

Biochim Biophys Acta Rev Cancer· January 2022

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Molecular dysregulations underlying the pathogenesis of endometriosis.
Vaishnavi Balasubramanian, Roshni Saravanan, Leena Dennis Joseph, Bhawna Dev, Shanmugasundaram Gouthaman, Suresh Kumar Rayala

Cell Signal· December 2021

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WaterMap and Molecular Dynamic Simulation-Guided Discovery of Potential PAK1 Inhibitors Using Repurposing Approaches.
Jayashree Biswal, Prajisha Jayaprakash, Suresh Kumar Rayala, Ganesh Venkatraman, Raghu Rangaswamy

ACS Omega· October 2021

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Small peptide inhibitor from the sequence of RUNX3 disrupts PAK1-RUNX3 interaction and abrogates its phosphorylation-dependent oncogenic function.
Rahul Kanumuri, Aruna Kumar Chelluboyina, Jayashree Biswal, Ravichandran Vignesh, Jaishree Pandian, Suresh K Rayala

Oncogene· August 2021

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KIBRA connects Hippo signaling and cancer.
Srikanth Swamy Swaroop B, Rahul Kanumuri, Inemai Ezhil, Jagadeesh Kumar Naidu Sampangi, Joachim Kremerskothen, Suresh Kumar Rayala

Exp Cell Res· June 2021

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Aberrant environment and PS-binding to calnuc C-terminal tail drives exosomal packaging and its metastatic ability.
Ravichandran Vignesh, Anita Sjölander, Ganesh Venkatraman, Suresh Kumar Rayala, Gopala Krishna Aradhyam

Biochem J· June 2021

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Clinical Evaluation of P21 Activated Kinase 1 (PAK1) Activation in Gliomas and Its Effect on Cell Proliferation.
Akkanapally Venu, Balasubramanian Archana, Rahul Kanumuri, Veena Kumari Vuttaradhi, Lawrence D'Cruze, Suresh Kumar Rayala

Cancer Invest· January 2021

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Sustainable production of camptothecin from an Alternaria sp. isolated from Nothapodytes nimmoniana.
I A H Khwajah Mohinudeen, Rahul Kanumuri, K N Soujanya, R Uma Shaanker, Suresh Kumar Rayala

Sci Rep· January 2021

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