Publications by authors named "Thomas Aune"

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Nanoparticle Delivery of Alu RNA Adjuvants Enhances Vaccine Immunogenicity.
Alexander J Kwiatkowski, Jacob A Schulman, Hayden M Pagendarm, Lucinda E Pastora, John T Tossberg, Thomas M Aune

ACS Appl Mater Interfaces· September 2025

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Increased unedited Alu RNA patterns found in cortex extracellular vesicles in Alzheimer's disease resemble hippocampus vasculature Alu RNA editing patterns but not cortex Alu RNA editing patterns.
Philip S Crooke, John T Tossberg, Thomas M Aune

J Alzheimers Dis· February 2025

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Nanoparticle Delivery of Immunostimulatory Alu RNA for Cancer Immunotherapy.
Kyle M Garland, Alexander J Kwiatkowski, John T Tossberg, Philip S Crooke, Thomas M Aune

Cancer Res Commun· September 2023

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Humanized anti-IL-26 monoclonal antibody as a novel targeted therapy for chronic graft-versus-host disease.
Ryo Hatano, Takumi Itoh, Haruna Otsuka, Harumi Saeki, Ayako Yamamoto, Thomas M Aune

Am J Transplant· December 2022

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Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease.
Philip S Crooke, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Thomas M Aune

Brain Commun· September 2022

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Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis.
Anna E Patrick, Kayla Shoaff, Tashawna Esmond, David M Patrick, David K Flaherty, Thomas M Aune

Front Immunol· July 2022

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Alu RNA Structural Features Modulate Immune Cell Activation and A-to-I Editing of Alu RNAs Is Diminished in Human Inflammatory Bowel Disease.
Thomas M Aune, John T Tossberg, Rachel M Heinrich, Krislyn P Porter, Philip S Crooke

Front Immunol· February 2022

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IL-26 mediates epidermal growth factor receptor-tyrosine kinase inhibitor resistance through endoplasmic reticulum stress signaling pathway in triple-negative breast cancer cells.
Takumi Itoh, Ryo Hatano, Yoshiya Horimoto, Taketo Yamada, Dan Song, Thomas M Aune

Cell Death Dis· May 2021

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Cutting Edge: Reduced Adenosine-to-Inosine Editing of Endogenous Alu RNAs in Severe COVID-19 Disease.
Philip S Crooke, John T Tossberg, Krislyn P Porter, Thomas M Aune

J Immunol· April 2021

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Reduced A-to-I editing of endogenous Alu RNAs in lung after SARS-CoV-2 infection.
Philip S Crooke, John T Tossberg, Krislyn P Porter, Thomas M Aune

Curr Res Immunol· April 2021

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Immunoprecipitation of DNA:RNA Hybrids Using the S9.6 Antibody.
Hunter R Gibbons, Thomas M Aune

Methods Mol Biol· March 2021

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Adenosine-to-Inosine RNA Editing of Alu Double-Stranded (ds)RNAs Is Markedly Decreased in Multiple Sclerosis and Unedited Alu dsRNAs Are Potent Activators of Proinflammatory Transcriptional Responses.
John T Tossberg, Rachel M Heinrich, Virginia M Farley, Philip S Crooke, Thomas M Aune

J Immunol· November 2020

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A simplified method to produce mRNAs and functional proteins from synthetic double-stranded DNA templates.
John T Tossberg, Tashawna M Esmond, Thomas M Aune

Biotechniques· October 2020

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Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.
Ryo Hatano, Takumi Itoh, Haruna Otsuka, Sayo Okamoto, Eriko Komiya, Thomas M Aune

MAbs· June 2020

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Methotrexate and its mechanisms of action in inflammatory arthritis.
Bruce N Cronstein, Thomas M Aune

Nat Rev Rheumatol· March 2020

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Divergent lncRNA Regulates Transcription in T-Helper 2 Cells.
Hunter R Gibbons, Guzel Shaginurova, Laura C Kim, Nathaniel Chapman, Charles F Spurlock, Thomas M Aune

Front Immunol· October 2019

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Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production.
Hunter R Gibbons, Deborah J Mi, Virginia M Farley, Tashawna Esmond, Mary B Kaood, Thomas M Aune

Sci Rep· July 2019

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Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis.
Maxwell J Heinrich, Caroline A Purcell, Andrea J Pruijssers, Yang Zhao, Charles F Spurlock, Thomas M Aune

J Autoimmun· June 2019

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Juvenile idiopathic arthritis associated with a mutation in GATA3.
Anna E Patrick, Wei Wang, Elly Brokamp, Thomas Brent Graham, Thomas M Aune

Arthritis Res Ther· June 2019

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Longitudinal changes in the expression of IL-33 and IL-33 regulated genes in relapsing remitting MS.
Subramaniam Sriram, Guzel Shaginurova, John T Tossberg, Chandramohan Natarajan, Charles F Spurlock, Thomas M Aune

PLoS One· May 2019

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Biological Effects of IL-26 on T Cell-Mediated Skin Inflammation, Including Psoriasis.
Takumi Itoh, Ryo Hatano, Eriko Komiya, Haruna Otsuka, Yuka Narita, Thomas M Aune

J Invest Dermatol· April 2019

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Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells.
Charles F Spurlock, Guzel Shaginurova, John T Tossberg, Jonathan D Hester, Nathaniel Chapman, Thomas M Aune

J Immunol· July 2017

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Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.
Charles F Spurlock, Philip S Crooke, Thomas M Aune

J Immunol· December 2016

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Long non-coding RNAs in innate and adaptive immunity.
Thomas M Aune, Charles F Spurlock

Virus Res· January 2016

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Long noncoding RNAs in T lymphocytes.
Thomas M Aune, Phillip S Crooke, Charles F Spurlock

J Leukoc Biol· January 2016

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