Publications by authors named "Thomas Bernhardt"

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Conformational regulation of two essential activators of bacterial cell elongation.
Morgan S A Gilman, Irina Shlosman, Daniel D Samé Guerra, Masy Domecillo, Elayne M Fivenson, Thomas G Bernhardt

Proc Natl Acad Sci U S A· November 2025

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The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall.
Elizabeth M Hart, Dieuwertje A de Bruin, Victoria M Marando, Marina Arnau Alemany, Eric D Snow, Thomas G Bernhardt

bioRxiv· October 2025

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The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch.
Irina Shlosman, Andrea Vettiger, Thomas G Bernhardt, Andrew C Kruse, Joseph J Loparo

Nat Commun· July 2025

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Intercepting a Mycobacterial Biosynthetic Pathway with Covalent Labeling.
Theodore C Warner, Victoria M Marando, Omar A Santiago-Reyes, Elizabeth M Hart, Stephanie R Smelyansky, Thomas G Bernhardt

J Am Chem Soc· April 2025

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The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the division site against osmotic rupture.
Paula P Navarro, Andrea Vettiger, Roman Hajdu, Virly Y Ananda, Alejandro López-Tavares, Thomas G Bernhardt

bioRxiv· April 2025

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A diverse single-stranded DNA-annealing protein library enables efficient genome editing across bacterial phyla.
Gabriel T Filsinger, Aaron Mychack, Evan Lyerly, Camilla Henriksen, Thomas M Bartlett, Thomas G Bernhardt

Proc Natl Acad Sci U S A· April 2025

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Using fluorescently labeled wheat germ agglutinin to track lipopolysaccharide transport to the outer membrane in .
Laurent Dubois, Andrea Vettiger, Jackson A Buss, Thomas G Bernhardt

mBio· March 2025

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PgpP is a broadly conserved phosphatase required for phosphatidylglycerol lipid synthesis.
Angelika Gründling, Anna P Brogan, Michael J James, Fernando H Ramirez-Guadiana, Ian J Roney, Thomas G Bernhardt

Proc Natl Acad Sci U S A· February 2025

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The mycomembrane.
Elizabeth M Hart, Thomas G Bernhardt

Curr Biol· February 2025

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The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch.
Irina Shlosman, Andrea Vettiger, Thomas G Bernhardt, Andrew C Kruse, Joseph J Loparo

bioRxiv· December 2024

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MreC-MreD structure reveals a multifaceted interface that controls MreC conformation.
Morgan S A Gilman, Irina Shlosman, Daniel D Samé Guerra, Masy Domecillo, Elayne M Fivenson, Thomas G Bernhardt

bioRxiv· October 2024

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Rapid discovery and evolution of nanosensors containing fluorogenic amino acids.
Erkin Kuru, Jonathan Rittichier, Helena de Puig, Allison Flores, Subhrajit Rout, Thomas G Bernhardt

Nat Commun· September 2024

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A potential space-making role in cell wall biogenesis for SltB1and DacB revealed by a beta-lactamase induction phenotype in .
Joël Gyger, Gabriel Torrens, Felipe Cava, Thomas G Bernhardt, Coralie Fumeaux

mBio· July 2024

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Co-ordinated assembly of the multilayered cell envelope of Gram-negative bacteria.
Elayne M Fivenson, Laurent Dubois, Thomas G Bernhardt

Curr Opin Microbiol· June 2024

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The conserved σD envelope stress response monitors multiple aspects of envelope integrity in corynebacteria.
Elizabeth M Hart, Evan Lyerly, Thomas G Bernhardt

PLoS Genet· June 2024

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Chemical Proteomics Strategies for Analyzing Protein Lipidation Reveal the Bacterial -Mycoloylome.
Nicholas Banahene, Trenton M Peters-Clarke, Kyle J Biegas, Evgenia Shishkova, Elizabeth M Hart, Thomas G Bernhardt

J Am Chem Soc· May 2024

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Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa.
Lindsey S Marmont, Anna K Orta, Becca W A Baileeves, David Sychantha, Ana Fernández-Galliano, Thomas G Bernhardt

Nat Microbiol· March 2024

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Physiological characterization of single-gene lysis proteins.
S Francesca Antillon, Thomas G Bernhardt, Karthik Chamakura, Ry Young

J Bacteriol· March 2024

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FacZ is a GpsB-interacting protein that prevents aberrant division-site placement in Staphylococcus aureus.
Thomas M Bartlett, Tyler A Sisley, Aaron Mychack, Suzanne Walker, Richard W Baker, Thomas G Bernhardt

Nat Microbiol· March 2024

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MacP bypass variants of PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases.
Caroline Midonet, Sean Bisset, Irina Shlosman, Felipe Cava, David Z Rudner, Thomas G Bernhardt

mBio· December 2023

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Single-molecule dynamics show a transient lipopolysaccharide transport bridge.
Lisa Törk, Caitlin B Moffatt, Thomas G Bernhardt, Ethan C Garner, Daniel Kahne

Nature· November 2023

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Physiological characterization of single gene lysis proteins.
S Francesca Antillon, Thomas G Bernhardt, Karthik Chamakura, Ry Young

bioRxiv· October 2023

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A feedback control mechanism governs the synthesis of lipid-linked precursors of the bacterial cell wall.
Lindsey S Marmont, Anna K Orta, Robin A Corey, David Sychantha, Ana Fernández Galliano, Thomas G Bernhardt

bioRxiv· August 2023

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A role for the Gram-negative outer membrane in bacterial shape determination.
Elayne M Fivenson, Patricia D A Rohs, Andrea Vettiger, Marios F Sardis, Grasiela Torres, Thomas G Bernhardt

Proc Natl Acad Sci U S A· August 2023

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Allosteric activation of cell wall synthesis during bacterial growth.
Irina Shlosman, Elayne M Fivenson, Morgan S A Gilman, Tyler A Sisley, Suzanne Walker, Thomas G Bernhardt

Nat Commun· June 2023

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