Publications by authors named "Thomas Seed"

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Development of PLX-R18, a promising and novel countermeasure for radiation-associated injuries.
Vijay K Singh, Arthur Machlenkin, Thomas M Seed

Drug Discov Today· November 2025

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Cutting-edge animal models for radiation combined injury drug development.
Vijay K Singh, Thomas M Seed

Expert Opin Drug Discov· November 2025

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Comparative Study of Pathology of Various Organs of Rhesus and Cynomolgus Nonhuman Primates Exposed to Two Different Doses of Acute Total-body Radiation.
Vijay K Singh, Stephen Y Wise, Oluseyi O Fatanmi, Sarah A Petrus, Issa Melendez-Miranda, Thomas M Seed

Radiat Res· September 2025

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New opportunities and current challenges using animal models for the discovery of novel countermeasures for acute radiation syndrome.
Vijay K Singh, Thomas M Seed

Expert Opin Drug Discov· August 2025

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Characterization of rhesus macaque model for cobalt-60 gamma-radiation source without use of blood product.
Stephen Y Wise, Oluseyi O Fatanmi, Sarah A Petrus, Issa Melendez-Miranda, Matthew Brink, Thomas M Seed

Sci Rep· August 2025

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Comparison of sensitivity of rhesus and cynomolgus macaque for acute radiation effects.
Vijay K Singh, Issa Melendez-Miranda, Oluseyi O Fatanmi, Stephen Y Wise, Alana D Carpenter, Thomas M Seed

Sci Rep· July 2025

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Lethality Assessments for Acutely Irradiated Cynomolgus Macaques Under Subject-based Care.
Issa Melendez-Miranda, Oluseyi O Fatanmi, Stephen Y Wise, Sarah A Petrus, Alana D Carpenter, Thomas M Seed

Radiat Res· May 2025

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New pharmaceutical-based strategies that foster the development and promulgation of globally effective medical countermeasures for radiation exposure injuries.
Vijay K Singh, Thomas M Seed

Expert Opin Pharmacother· August 2024

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Pathology of acute sub-lethal or near-lethal irradiation of nonhuman primates prophylaxed with the nutraceutical, gamma tocotrienol.
Vijay K Singh, Stephen Y Wise, Oluseyi O Fatanmi, Sarah A Petrus, Alana D Carpenter, Thomas M Seed

Sci Rep· June 2024

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Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol.
Vijay K Singh, Stephen Y Wise, Oluseyi O Fatanmi, Sarah A Petrus, Alana D Carpenter, Thomas M Seed

Sci Rep· March 2024

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The potential value of 5-androstenediol in countering acute radiation syndrome.
Vijay K Singh, Thomas M Seed

Drug Discov Today· February 2024

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Protein biomarkers for radiation injury and testing of medical countermeasure efficacy: promises, pitfalls, and future directions.
Vijay K Singh, Meera Srivastava, Thomas M Seed

Expert Rev Proteomics· November 2023

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Novel biomarkers for acute radiation injury and countermeasures using large and small animal models and multi-omics approach.
Vijay K Singh, Oluseyi O Fatanmi, Stephen Y Wise, Alana D Carpenter, Brianna Janocha, Thomas M Seed

Radiat Prot Dosimetry· September 2023

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Radiosensitivity of rhesus nonhuman primates: consideration of sex, supportive care, body weight, and age at time of exposure.
Vijay K Singh, Alana D Carpenter, Brianna L Janocha, Sarah A Petrus, Oluseyi O Fatanmi, Thomas M Seed

Expert Opin Drug Discov· July 2023

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The safety and efficacy of interleukin 11 for radiation injury.
Vijay K Singh, Thomas M Seed

Expert Opin Drug Saf· February 2023

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Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: current status and future perspectives.
Vijay K Singh, Thomas M Seed

Expert Opin Investig Drugs· January 2023

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Armed Forces Radiobiology Research Institute/Uniformed Services University of the Health Sciences perspective on space radiation countermeasure discovery.
Vijay K Singh, Thomas M Seed

Life Sci Space Res (Amst)· November 2022

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Acute radiation syndrome drug discovery using organ-on-chip platforms.
Vijay K Singh, Thomas M Seed

Expert Opin Drug Discov· August 2022

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An update on romiplostim for treatment of acute radiation syndrome.
Vijay K Singh, Thomas M Seed

Drugs Today (Barc)· March 2022

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Radiation countermeasures for hematopoietic acute radiation syndrome: growth factors, cytokines and beyond.
Vijay K Singh, Thomas M Seed

Int J Radiat Biol· January 2022

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How necessary are animal models for modern drug discovery?
Vijay K Singh, Thomas M Seed

Expert Opin Drug Discov· December 2021

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What are the practical, ethical and pathobiological considerations in the use of minipigs as an animal model in drug discovery for acute radiation syndrome and delayed effects of acute radiation exposure?
Doreswamy Kenchegowda, Thomas M Seed, Vijay K Singh

Expert Opin Drug Discov· August 2021

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Metabolomics-based predictive biomarkers of radiation injury and countermeasure efficacy: current status and future perspectives.
Vijay K Singh, Thomas M Seed, Amrita K Cheema

Expert Rev Mol Diagn· July 2021

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Analysis of the metabolomic profile in serum of irradiated nonhuman primates treated with Ex-Rad, a radiation countermeasure.
Yaoxiang Li, Michael Girgis, Stephen Y Wise, Oluseyi O Fatanmi, Thomas M Seed

Sci Rep· June 2021

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Repurposing Pharmaceuticals Previously Approved by Regulatory Agencies to Medically Counter Injuries Arising Either Early or Late Following Radiation Exposure.
Vijay K Singh, Thomas M Seed

Front Pharmacol· May 2021

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