Publications by authors named "Tie Lin Yang"

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Long noncoding RNA LINC00339 promotes osteoporosis development via modulating of regulator CDC42 by binding PARP1.
Dong-Li Zhu, Yan Zhang, Xiao-Yu Zhang, Zi-Han Qiu, Ke Li, Tie-Lin Yang, Bo Yang

Noncoding RNA Res· December 2025

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Revealing the genetic architectures underlying organ-specific aging based on proteomic data.
Ren-Jie Zhu, Yan Guo, Jia-Hao Wang, Ke Yu, Wei Shi, Tie-Lin Yang

Nat Commun· December 2025

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Advances in functional mechanisms of genomic G-quadruplex structures in transcriptional regulation.
Zhen-Zhen He, Xiao-Feng Chen, Yue Hou, Tie-Lin Yang, Bo Yang

Yi Chuan· December 2025

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Genetic Insights into Head-to-Body Ratios Via Deep Learning-Based Image Segmentation and Implications for Common Diseases.
Wei Shi, Shan-Shan Dong, Ren-Jie Zhu, Shi-Hao Tang, Jia-Hao Wang, Tie-Lin Yang

Nat Commun· December 2025

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Review of diffusion models and its applications in biomedical informatics.
Jiawei Luo, Liren Yang, Yan Liu, Changbao Hu, Grant Wang, Yan Yang, Tie-Lin Yang

BMC Med Inform Decis Mak· October 2025

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Plasma Metabolomics and Machine Learning Reveals Metabolic Alterations and Diagnostic Biomarkers for Deep Venous Thrombosis in Hypertensive Patients after Traumatic Fracture.
Mukhtar Aliyu, Kun Zhang, Shi-Hao Tang, Jia-Hao Wang, Hao Wu, Tie-Lin Yang

J Proteome Res· August 2025

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Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases.
Jia-Hao Wang, Shan-Shan Dong, Wei Huang, Hao-An Wang, Shao-Shan Liu, Tie-Lin Yang

Cardiovasc Diabetol· August 2025

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Blood plasma proteome-wide association study implicates new proteins in type 2 diabetes mellitus pathogenesis.
Yang Yang, Jia-Hao Wang, Hao-An Wang, Tian-Pei Zhang, Guanchen Liu, Tie-Lin Yang

J Clin Endocrinol Metab· August 2025

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The function of GPCRs in different bone cells.
Yan Zhang, Nai-Ning Wang, Zi-Han Qiu, Jia-Hao Wang, Wen-Na An, Tie-Lin Yang

Int J Biol Sci· August 2025

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Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis.
Wen Tian, Shan-Shan Dong, Feng Jiang, Jun-Qi Zhang, Chen Wang, Zhi Yang, Tie-Lin Yang

EBioMedicine· July 2025

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Synovial transcriptome-wide association study implicates novel genes underlying rheumatoid arthritis risk.
Shou-Ye Hu, Feng Jiang, Hui-Miao Song, Ya-Kang Wang, Wen Tian, Tie-Lin Yang, Zhi Yang

Rheumatology (Oxford)· May 2025

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Exploring the research hotspots and trends in genetic education reform.
Yan Guo, Da-Jin Zhang, Dong-Li Zhu, Shan-Shan Dong, Tie-Lin Yang

Yi Chuan· April 2025

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RUNX2 Phase Separation Mediates Long-Range Regulation Between Osteoporosis-Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation.
Yan Zhang, Xin-Hao Li, Pai Peng, Zi-Han Qiu, Chen-Xi Di, Zhi Yang, Tie-Lin Yang

Adv Sci (Weinh)· February 2025

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Systematic functional characterization of non-coding regulatory SNPs associated with central obesity.
Shan-Shan Dong, Yuan-Yuan Duan, Ren-Jie Zhu, Ying-Ying Jia, Jia-Xin Chen, Tie-Lin Yang

Am J Hum Genet· January 2025

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The Causal Relationships Between Gut Microbiota, Brain Volume, and Intelligence: A Two-Step Mendelian Randomization Analysis.
Shi Yao, Ji-Zhou Han, Jing Guo, Xin Wang, Long Qian, Tie-Lin Yang

Biol Psychiatry· September 2024

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Two-sample Mendelian randomization analysis reveals causal relationships between blood lipids and venous thromboembolism.
Wei Huang, Yan Zou, Kun Zhang, Shi Yao, Shi-Hao Tang, Tie-Lin Yang

Haematologica· September 2024

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Unveiling Promising Neuroimaging Biomarkers for Schizophrenia Through Clinical and Genetic Perspectives.
Jing Guo, Changyi He, Huimiao Song, Huiwu Gao, Shi Yao, Tie-Lin Yang

Neurosci Bull· September 2024

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Integrated landscape of plasma metabolism and proteome of patients with post-traumatic deep vein thrombosis.
Kun Zhang, Pengfei Wang, Wei Huang, Shi-Hao Tang, Hanzhong Xue, Na Yang, Dongyang Li, Tie-Lin Yang

Nat Commun· September 2024

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Blood metabolites, neurocognition and psychiatric disorders: a Mendelian randomization analysis to investigate causal pathways.
Jing Guo, Ping Yang, Jia-Hao Wang, Shi-Hao Tang, Ji-Zhou Han, Tie-Lin Yang

Transl Psychiatry· September 2024

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Revealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression.
Ruo-Han Hao, Tian-Pei Zhang, Feng Jiang, Jun-Hui Liu, Shan-Shan Dong, Tie-Lin Yang

Nat Commun· June 2024

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Isolation and culture of human primary osteoblasts: Comparing the effects of differences in method details on osteoblast characteristics.
Fei Chen, Yan Zhang, Pai Peng, Xiao-Ting Huang, Zi-Han Qiu, Tie-Lin Yang, Bo Yang

Genes Dis· March 2024

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Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis.
Xiao-Feng Chen, Yuan-Yuan Duan, Ying-Ying Jia, Qian-Hua Dong, Wei Shi, Tie-Lin Yang

Cell Genom· March 2024

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A landscape of gene expression regulation for synovium in arthritis.
Feng Jiang, Shou-Ye Hu, Wen Tian, Nai-Ning Wang, Ning Yang, Zhi Yang, Tie-Lin Yang

Nat Commun· February 2024

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Multi-tissue transcriptome-wide association study reveals susceptibility genes and drug targets for insulin resistance-relevant phenotypes.
Yuan-Yuan Duan, Xin Ke, Hao Wu, Shi Yao, Wei Shi, Tie-Lin Yang

Diabetes Obes Metab· January 2024

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High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes.
Yuan-Yuan Duan, Xiao-Feng Chen, Ren-Jie Zhu, Ying-Ying Jia, Xiao-Ting Huang, Ning Yang, Tie-Lin Yang

Am J Hum Genet· August 2023

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