Publications by authors named "Tim Karl"

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Therapeutic properties of multi-cannabinoid treatment strategies for Alzheimer's disease.
Madilyn Coles, Genevieve Z Steiner-Lim, Tim Karl

Front Neurosci· September 2022

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Knock-out of Tpm4.2/Actin Filaments Alters Neuronal Signaling, Neurite Outgrowth, and Behavioral Phenotypes in Mice.
Sian Genoud, Chanchanok Chaichim, Rossana Rosa Porto, Tamara Tomanic, Holly Stefen, Tim Karl

Mol Neurobiol· December 2025

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Combination treatment with medium dose THC and CBD had no therapeutic effect in a transgenic mouse model for Alzheimer's disease but affected other domains including anxiety-related behaviours and object recognition memory.
Beate Aumer, Rossana Rosa Porto, Madilyn Coles, Nina Ulmer, Georgia Watt, Tim Karl

Pharmacol Biochem Behav· December 2025

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Cannabidiol Modulates Brain Copper Homeostasis in Wild-Type-Like But Not Alzheimer's Disease Transgenic Female Mice: Implications for Neuroprotective Therapy.
Anthony Dosseto, Kaila Tonge, Tim Karl

Mol Neurobiol· November 2025

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Behavioural effects of oral cannabidiol (CBD) treatment in the superoxide dismutase 1 G93 A (SOD1) mouse model of amyotrophic lateral sclerosis.
Sandip Ghimire, Fabian Kreilaus, Rossana Rosa Porto, Lyndsey L Anderson, Justin J Yerbury, Tim Karl

Psychopharmacology (Berl)· September 2025

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Sex-dependent Schizophrenia and Drug Reward Behavioral Phenotypes in Metabotropic Glutamate 5 Receptor Heterozygous and Homozygous Mice.
Rossana Rosa Porto, Fabian Kreilaus, Anthony J Hannan, Rose Chesworth, Tim Karl

Schizophr Bull· September 2025

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Persistent behavioural consequences of chronic adolescent cannabidiol (CBD) in a mouse model with increased susceptibility to Δ-tetrahydrocannabinol and schizophrenia.
Gabriela Visini, Rose Chesworth, Tim Karl

Prog Neuropsychopharmacol Biol Psychiatry· April 2025

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Cannabidiol (CBD) facilitates cocaine extinction and ameliorates cocaine-induced changes to the gut microbiome in male C57BL/6JArc mice.
Rose Chesworth, Howard Chi-Ho Yim, Georgia Watt, Emad El-Omar, Tim Karl

Prog Neuropsychopharmacol Biol Psychiatry· July 2024

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Chronic interleukin-6 mediated neuroinflammation decreases anxiety, and impaires spatial memory in aged female mice.
Ingrid Marguerite Wagnon, Lillian Jocelyn Jabur, Garry Niedermayer, Gerald Münch, Tim Karl

Front Neurosci· November 2023

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Light phase does not affect operant sucrose self-administration in adult male C57BL/6JAbr mice.
Georgia Watt, Tim Karl, Rose Chesworth

Behav Brain Res· October 2023

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Impaired extinction of operant cocaine in a genetic mouse model of schizophrenia risk.
Rose Chesworth, Gabriela Visini, Tim Karl

Psychopharmacology (Berl)· July 2023

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Voluntary exercise modulates pathways associated with amelioration of retinal degenerative diseases.
Joshua A Chu-Tan, Adrian V Cioanca, Yvette Wooff, Max Kirkby, Marissa Ellis, Tim Karl

Front Physiol· March 2023

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The effects of preventative cannabidiol in a male mouse model of schizophrenia.
Gabriela Visini, Samara Brown, Katrina Weston-Green, Cynthia Shannon Weickert, Rose Chesworth, Tim Karl

Front Cell Neurosci· November 2022

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Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease.
Yuanyuan Deng, Mian Bi, Fabien Delerue, Shelley L Forrest, Gabriella Chan, Tim Karl

Acta Neuropathol· October 2022

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Effect of long-term cannabidiol on learning and anxiety in a female Alzheimer's disease mouse model.
Rose Chesworth, David Cheng, Chloe Staub, Tim Karl

Front Pharmacol· September 2022

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Characterisation of the Mouse Cerebellar Proteome in the GFAP-IL6 Model of Chronic Neuroinflammation.
Rustam Asgarov, Monokesh K Sen, Meena Mikhael, Tim Karl, Erika Gyengesi

Cerebellum· June 2022

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Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice.
Fabian Kreilaus, Magdalena Przybyla, Lars Ittner, Tim Karl

Behav Brain Res· May 2022

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Editorial: Looking at the Complete Picture: Tackling Broader Factors Important for Advancing the Validity of Preclinical Models in Disease.
Tim Karl, Jess Nithianantharajah, Ulrike Weber-Stadlbauer

Front Behav Neurosci· April 2022

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Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis .
Utpal Kumar Adhikari, Elif Sakiz, Umma Habiba, Meena Mikhael, Matteo Senesi, Tim Karl

Heliyon· December 2021

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Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity.
Utpal Kumar Adhikari, Elif Sakiz, Xian Zhou, Umma Habiba, Sachin Kumar, Tim Karl

Front Immunol· September 2021

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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 mice with a C57BL/6 background.
Jeremy S Lum, Mikayla L Brown, Natalie E Farrawell, Luke McAlary, Diane Ly, Tim Karl

Sci Rep· September 2021

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PredictProtein - Predicting Protein Structure and Function for 29 Years.
Michael Bernhofer, Christian Dallago, Tim Karl, Venkata Satagopam, Michael Heinzinger

Nucleic Acids Res· July 2021

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Spatial Memory and Microglia Activation in a Mouse Model of Chronic Neuroinflammation and the Anti-inflammatory Effects of Apigenin.
Rose Chesworth, Rashmi Gamage, Faheem Ullah, Sandra Sonego, Christopher Millington, Tim Karl

Front Neurosci· July 2021

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Behavioural effects of cage systems on the G93A Superoxide Dismutase 1 transgenic mouse model for amyotrophic lateral sclerosis.
Stefan Guerra, Roger Chung, Justin Yerbury, Tim Karl

Genes Brain Behav· June 2021

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Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia.
Stefan Guerra, Rose Chesworth, Cynthia Shannon Weickert, Tim Karl

Behav Brain Res· May 2021

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