Publications by authors named "Timothy Dalton"

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Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis.
Ying Chen, Katherine D Holland, Howard G Shertzer, Daniel W Nebert, Timothy P Dalton

Antioxidants (Basel)· February 2023

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Rates of return to sorghum and millet research investments: A meta-analysis.
Yacob A Zereyesus, Timothy J Dalton

PLoS One· September 2017

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Generation of a Slc39a8 hypomorph mouse: markedly decreased ZIP8 Zn²⁺/(HCO₃⁻)₂ transporter expression.
Bin Wang, Lei He, Hongbin Dong, Timothy P Dalton, Daniel W Nebert

Biochem Biophys Res Commun· July 2011

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Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.
Ying Chen, Elisabet Johansson, Yi Yang, Marian L Miller, Dongxiao Shen, Timothy P Dalton

J Hepatol· December 2010

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Glutathione deficient C57BL/6J mice are not sensitized to ozone-induced lung injury.
Elisabet Johansson, Scott C Wesselkamper, Howard G Shertzer, George D Leikauf, Timothy P Dalton

Biochem Biophys Res Commun· May 2010

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Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors.
Pascal Steullet, Jan-Harry Cabungcal, Anita Kulak, Rudolf Kraftsik, Ying Chen, Timothy P Dalton

J Neurosci· February 2010

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Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit.
Ying Chen, Elisabet Johansson, Yunxia Fan, Howard G Shertzer, Vasilis Vasiliou, Timothy P Dalton

Free Radic Biol Med· August 2009

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Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.
Hongbin Dong, Timothy P Dalton, Marian L Miller, Ying Chen, Shigeyuki Uno

Mol Pharmacol· March 2009

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Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.
Suzie Lavoie, Ying Chen, Timothy P Dalton, René Gysin, Michel Cuénod

J Neurochem· March 2009

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Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter.
Kuppuswami Girijashanker, Lei He, Manoocher Soleimani, Jodie M Reed, Hong Li, Timothy P Dalton

Mol Pharmacol· May 2008

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Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.
Shigeyuki Uno, Nadine Dragin, Marian L Miller, Timothy P Dalton, Frank J Gonzalez

Free Radic Biol Med· February 2008

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Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: kinetics, electrogenicity and trafficking.
Zhiwei Liu, Hong Li, Manoocher Soleimani, Kuppuswami Girijashanker, Jodie M Reed, Timothy P Dalton

Biochem Biophys Res Commun· January 2008

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Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.
Jonathan M Maher, Matthew Z Dieter, Lauren M Aleksunes, Angela L Slitt, Grace Guo, Timothy P Dalton

Hepatology· November 2007

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Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line.
Nadine Dragin, Shigeyuki Uno, Bin Wang, Timothy P Dalton, Daniel W Nebert

Biochem Biophys Res Commun· August 2007

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Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase.
Yi Yang, Ying Chen, Elisabet Johansson, Scott N Schneider, Howard G Shertzer, Timothy P Dalton

Biochem Pharmacol· July 2007

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7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.
Howard G Shertzer, Mary B Genter, Glenn Talaska, Christine P Curran, Daniel W Nebert, Timothy P Dalton

Carcinogenesis· June 2007

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Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure.
Ying Chen, Yi Yang, Marian L Miller, Dongxiao Shen, Howard G Shertzer, Timothy P Dalton

Hepatology· May 2007

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Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line.
Bin Wang, Scott N Schneider, Nadine Dragin, Kuppuswami Girijashanker, Timothy P Dalton

Am J Physiol Cell Physiol· April 2007

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Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.
Ling Gao, Jiakun Wang, Konjeti R Sekhar, Huiyong Yin, Nicholas F Yared, Timothy P Dalton

J Biol Chem· January 2007

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TCDD decreases ATP levels and increases reactive oxygen production through changes in mitochondrial F(0)F(1)-ATP synthase and ubiquinone.
Howard G Shertzer, Mary Beth Genter, Dongxiao Shen, Daniel W Nebert, Ying Chen, Timothy P Dalton

Toxicol Appl Pharmacol· December 2006

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The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.
Daniel W Nebert, Timothy P Dalton

Nat Rev Cancer· December 2006

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Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.
Mary Beth Genter, Jennifer Marlowe, J Kevin Kerzee, Nadine Dragin, Alvaro Puga, Timothy P Dalton

Biochem Biophys Res Commun· September 2006

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For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.
Nadine Dragin, Timothy P Dalton, Marian L Miller, Howard G Shertzer, Daniel W Nebert

J Biol Chem· July 2006

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ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties.
Lei He, Kuppuswami Girijashanker, Timothy P Dalton, Jodie Reed, Hong Li

Mol Pharmacol· July 2006

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Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor.
John F Reichard, Timothy P Dalton, Howard G Shertzer, Alvaro Puga

Dose Response· May 2006

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