Publications by authors named "Toby A Dite"

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Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
Michael J Roy, Minglyanna G Surudoi, Ashleigh Kropp, Jianmei Hou, Weiwen Dai, Joshua M Hardy, Lung-Yu Liang, Thomas R Cotton, Bernhard C Lechtenberg, Toby A Dite

Nat Commun· June 2023

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Unconventional binding of calmodulin to CHK2 kinase inhibits catalytic activity.
Christopher R Horne, Tingting Wang, Samuel N Young, Toby A Dite, Hunter G Nyvall

Biochem J· December 2025

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Structural basis for Porcupine inhibition.
Katrina A Black, Jesse I Mobbs, Hariprasad Venugopal, Toby A Dite, Andrew Leis

Commun Chem· November 2025

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Cryo-EM structure of endogenous Pfs230 and Pfs48/45 fertilization complex.
Melanie H Dietrich, Jill Chmielewski, Li-Jin Chan, Li Lynn Tan, Amy Adair, Toby A Dite

Science· September 2025

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MORC2 is a phosphorylation-dependent DNA compaction machine.
Winnie Tan, Jeongveen Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Toby A Dite

Nat Commun· July 2025

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Measuring Cellular Adenine Nucleotides by Liquid Chromatography-Coupled Mass Spectrometry.
Ashley J Ovens, Dingyi Yu, Toby A Dite, Bruce E Kemp, Jonathan S Oakhill

Methods Mol Biol· May 2025

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PSKH1 kinase activity is differentially modulated via allosteric binding of Ca sensor proteins.
Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley

Proc Natl Acad Sci U S A· February 2025

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Caspase-2 protects against ferroptotic cell death.
Swati Dawar, Mariana C Benitez, Yoon Lim, Toby A Dite, Jumana M Yousef

Cell Death Dis· March 2024

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Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin.
Kaiseal T G Sarson-Lawrence, Joshua M Hardy, Josephine Iaria, Dina Stockwell, Kira Behrens, Toby A Dite

Nat Commun· February 2024

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Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism.
Nolan J Hoffman, Jamie Whitfield, Natalie R Janzen, Mehdi R Belhaj, Sandra Galic, Toby A Dite

Mol Metab· November 2020

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CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
Christopher G Langendorf, Matthew T O'Brien, Kevin R W Ngoei, Luke M McAloon, Urmi Dhagat, Toby A Dite

J Biol Chem· November 2020

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mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.
Naomi X Y Ling, Adrian Kaczmarek, Ashfaqul Hoque, Elizabeth Davie, Kevin R W Ngoei, Toby A Dite

Nat Metab· January 2020

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Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone.
Christina Vrahnas, Martha Blank, Toby A Dite, Liliana Tatarczuch, Niloufar Ansari

Nat Commun· November 2019

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Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone.
Christina Vrahnas, Martha Blank, Toby A Dite, Liliana Tatarczuch, Niloufar Ansari

Nat Commun· July 2019

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Transient Expression of AMPK Heterotrimer Complexes in Mammalian Cells.
Jonathan S Oakhill, John W Scott, Toby A Dite

Methods Mol Biol· January 2019

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Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4.
Kevin R W Ngoei, Christopher G Langendorf, Naomi X Y Ling, Ashfaqul Hoque, Swapna Varghese, Toby A Dite

Cell Chem Biol· June 2018

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AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965.
Toby A Dite, Christopher G Langendorf, Ashfaqul Hoque, Sandra Galic, Richard J Rebello

J Biol Chem· June 2018

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Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.
Lisa M Lindqvist, Daniel Frank, Kate McArthur, Toby A Dite, Michael Lazarou

Cell Death Differ· March 2018

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The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs.
Toby A Dite, Naomi X Y Ling, John W Scott, Ashfaqul Hoque, Sandra Galic

Nat Commun· September 2017

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Impact of Genetic Variation on Human CaMKK2 Regulation by Ca-Calmodulin and Multisite Phosphorylation.
Matthew T O'Brien, Jonathan S Oakhill, Naomi X Y Ling, Christopher G Langendorf, Ashfaqul Hoque, Toby A Dite

Sci Rep· February 2017

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Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder.
John W Scott, Elizabeth Park, Ramona M Rodriguiz, Jonathan S Oakhill, Samah M A Issa, Toby A Dite

Sci Rep· September 2015

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Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release.
John W Scott, Sandra Galic, Kate L Graham, Richard Foitzik, Naomi X Y Ling, Toby A Dite

Chem Biol· June 2015

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Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling.
John W Scott, Naomi Ling, Samah M A Issa, Toby A Dite, Matthew T O'Brien

Chem Biol· May 2014

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