Publications by authors named "Tri Hung Nguyen"

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Development of a First-in-Class Click Chemistry-Based Cancer Therapeutic, from Preclinical Evaluation to a First-in-Human Dose Escalation Clinical Trial.
Sangeetha Srinivasan, Nathan A Yee, Maša Alečković, Michael Zakharian, Amir Mahmoodi, Tri-Hung Nguyen

Clin Cancer Res· September 2025

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Application of immunocapture and nanoflow LC-MS/MS to overcome the barriers to the quantitation of oxytocin in plasma of women in third stage labour.
Sebastiaan Bijttebier, Tri-Hung Nguyen, Michelle P McIntosh, Carl Kirkpatrick, Bart Remmerie

Br J Clin Pharmacol· October 2024

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Exploring the role of ex vivo metabolism on blood and plasma measurements of oxytocin among women in the third stage of labour: A post hoc study.
Victoria L Oliver, Sarah Siederer, Anthony Cahn, Katarzyna Gajewska-Knapik, Rachel A Gibson, Tri-Hung Nguyen

Br J Clin Pharmacol· December 2023

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Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep.
Anne Weiss, Robert J Bischof, Cornelia B Landersdorfer, Tri-Hung Nguyen, Andrew Davies

Pharm Res· August 2023

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Click Chemistry Selectively Activates an Auristatin Protodrug with either Intratumoral or Systemic Tumor-Targeting Agents.
Jesse M McFarland, Maša Alečković, George Coricor, Sangeetha Srinivasan, Matthew Tso, Tri-Hung Nguyen

ACS Cent Sci· July 2023

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SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species.
Sangeetha Srinivasan, Nathan A Yee, Michael Zakharian, Maša Alečković, Amir Mahmoodi, Tri-Hung Nguyen

bioRxiv· March 2023

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Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids.
Anthony Lai, Nathania Leong, Dan Zheng, Leigh Ford, Tri-Hung Nguyen

Pharm Res· October 2022

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Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy.
Chandra Sekhar Boddupalli, Shiny Nair, Glenn Belinsky, Joseph Gans, Erin Teeple, Tri-Hung Nguyen

Elife· August 2022

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Polymeric Nanotubes as Drug Delivery Vectors─Comparison of Covalently and Supramolecularly Assembled Constructs.
Andrew Kerr, Erny Sagita, Edward D H Mansfield, Tri-Hung Nguyen, Orlagh M Feeney

Biomacromolecules· June 2022

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Digestion of Lipid-Based Formulations Not Only Mediates Changes to Absorption of Poorly Soluble Drugs Due to Differences in Solubilization But Also Reflects Changes to Thermodynamic Activity and Permeability.
Yusuke Tanaka, Tri-Hung Nguyen, Estelle J A Suys, Christopher J H Porter

Mol Pharm· April 2021

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Stabilising disproportionation of lipophilic ionic liquid salts in lipid-based formulations.
Anthony Lai, Yasemin Sahbaz, Leigh Ford, Tri-Hung Nguyen, Shadabul Haque

Int J Pharm· March 2021

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A Phase 1, Randomised, Placebo-Controlled, Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of Cannabidiol in Fed Healthy Volunteers.
Daniel Perkins, Juliet Butler, Katherine Ong, Tri-Hung Nguyen, Susan Cox

Eur J Drug Metab Pharmacokinet· October 2020

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API ionic liquids: probing the effect of counterion structure on physical form and lipid solubility.
Leigh Ford, Erin Tay, Tri-Hung Nguyen, Hywel D Williams, Hassan Benameur

RSC Adv· March 2020

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Quantifying In Vivo Luminal Drug Solubilization -Supersaturation-Precipitation Profiles to Explain the Performance of Lipid Based Formulations.
Yusuke Tanaka, Erin Tay, Tri-Hung Nguyen, Christopher J H Porter

Pharm Res· February 2020

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Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats.
Ian K Styles, Orlagh M Feeney, Tri-Hung Nguyen, Daniel H S Brundel, David W Kang

J Control Release· December 2019

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Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure.
Erin Tay, Tri-Hung Nguyen, Leigh Ford, Hywel D Williams, Hassan Benameur

Pharmaceutics· December 2019

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Temperature stability of oxytocin ampoules labelled for storage at 2°C-8°C and below 25°C: an observational assessment under controlled accelerated and temperature cycling conditions.
Tri-Hung Nguyen, Peter Lambert, Rajpreet Singh Minhas, Claire McEvoy, Kim Deadman

BMJ Open· July 2019

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Quality of oxytocin ampoules available in health care facilities in the Democratic Republic of Congo: an exploratory study in five provinces.
Peter Lambert, Tri-Hung Nguyen, Claire McEvoy, Rajpreet Singh Minhas, Philip Wright

J Glob Health· December 2018

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Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution.
Sophie C Larnaudie, Joaquin Sanchis, Tri-Hung Nguyen, Raoul Peltier, Sylvain Catrouillet

Biomaterials· September 2018

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Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.
Yasemin Sahbaz, Tri-Hung Nguyen, Leigh Ford, Claire L McEvoy, Hywel D Williams

Mol Pharm· November 2017

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Templated Polymer Replica Nanoparticles to Facilitate Assessment of Material-Dependent Pharmacokinetics and Biodistribution.
Danzi Song, Jiwei Cui, Huanli Sun, Tri-Hung Nguyen, Sheilajen Alcantara

ACS Appl Mater Interfaces· October 2017

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Substantial Targeting Advantage Achieved by Pulmonary Administration of Colistin Methanesulfonate in a Large-Animal Model.
Cornelia B Landersdorfer, Tri-Hung Nguyen, Linh Thuy Lieu, Gary Nguyen, Robert J Bischof

Antimicrob Agents Chemother· January 2017

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Addition of 20-kDa PEG to Insulin Lispro Alters Absorption and Decreases Clearance in Animals.
Mary Pat Knadler, Tri-Hung Nguyen, Kristina Campanale, Michael J De Veer, John M Beals

Pharm Res· December 2016

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In Vivo Formation of Cubic Phase in Situ after Oral Administration of Cubic Phase Precursor Formulation Provides Long Duration Gastric Retention and Absorption for Poorly Water-Soluble Drugs.
Anna C Pham, Linda Hong, Oliver Montagnat, Cameron J Nowell, Tri-Hung Nguyen

Mol Pharm· January 2016

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Pluronic-Functionalized Silica-Lipid Hybrid Microparticles: Improving the Oral Delivery of Poorly Water-Soluble Weak Bases.
Shasha Rao, Katharina Richter, Tri-Hung Nguyen, Ben J Boyd, Christopher J H Porter

Mol Pharm· December 2015

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