Publications by authors named "Ulrich Matzner"

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Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophy.
Murtadha Al-Saady, Shanice Beerepoot, Bonnie C Plug, Marjolein Breur, Hristina Galabova, Petra J W Pouwels, Jaap-Jan Boelens, Caroline Lindemans, Peter M van Hasselt, Ulrich Matzner

July 2023

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Data-Independent Acquisition-Parallel Reaction Monitoring Acquisition Reveals Age-Dependent Alterations of the Lysosomal Proteome in a Mouse Model of Metachromatic Leukodystrophy.
Anne Sanner, Robert Hardt, Ulrich Matzner, Dominic Winter

Anal Chem· December 2024

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Engineered arylsulfatase A with increased activity, stability and brain delivery for therapy of metachromatic leukodystrophy.
Claudia Yaghootfam, Marc Sylvester, Boris Turk, Volkmar Gieselmann, Ulrich Matzner

Mol Ther· October 2023

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Deletion of fatty acid amide hydrolase reduces lyso-sulfatide levels but exacerbates metachromatic leukodystrophy in mice.
Claudia Yaghootfam, Bernd Gehrig, Marc Sylvester, Volkmar Gieselmann, Ulrich Matzner

J Biol Chem· September 2021

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Brain cell type-specific endocytosis of arylsulfatase A identifies limitations of enzyme-based therapies for metachromatic leukodystrophy.
Debora Kaminski, Claudia Yaghootfam, Frank Matthes, Annika Reßing, Volkmar Gieselmann, Ulrich Matzner

Hum Mol Genet· February 2021

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Metachromatic leukodystrophy and transplantation: remyelination, no cross-correction.
Nicole I Wolf, Marjolein Breur, Bonnie Plug, Shanice Beerepoot, Aimee S R Westerveld, Ulrich Matzner

Ann Clin Transl Neurol· February 2020

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Evolutionary redesign of the lysosomal enzyme arylsulfatase A increases efficacy of enzyme replacement therapy for metachromatic leukodystrophy.
Heidi Simonis, Claudia Yaghootfam, Marc Sylvester, Volkmar Gieselmann, Ulrich Matzner

Hum Mol Genet· June 2019

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Potential of surfactant-coated nanoparticles to improve brain delivery of arylsulfatase A.
Tilman Schuster, Astrid Mühlstein, Claudia Yaghootfam, Olga Maksimenko, Elena Shipulo, Ulrich Matzner

J Control Release· May 2017

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Enzyme replacement therapy of a novel humanized mouse model of globoid cell leukodystrophy.
Frank Matthes, Claes Andersson, Axel Stein, Carl Eistrup, Jens Fogh, Ulrich Matzner

Exp Neurol· September 2015

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Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.
Jonas Doerr, Annika Böckenhoff, Benjamin Ewald, Julia Ladewig, Matthias Eckhardt, Ulrich Matzner

Mol Ther· September 2015

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Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy.
Axel Stein, Stijn Stroobants, Volkmar Gieselmann, Rudi D'Hooge, Ulrich Matzner

Mol Ther· July 2015

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Comparison of five peptide vectors for improved brain delivery of the lysosomal enzyme arylsulfatase A.
Annika Böckenhoff, Sandra Cramer, Philipp Wölte, Simeon Knieling, Claudia Wohlenberg, Ulrich Matzner

J Neurosci· February 2014

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Lysosomal di-N-acetylchitobiase-deficient mouse tissues accumulate Man2GlcNAc2 and Man3GlcNAc2.
Emanuele Persichetti, Katharina Klein, Silvia Paciotti, Karine Lecointe, Chiara Balducci, Ulrich Matzner

Biochim Biophys Acta· July 2012

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Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age.
Frank Matthes, Stijn Stroobants, Debora Gerlach, Claudia Wohlenberg, Carsten Wessig, Ulrich Matzner

Hum Mol Genet· June 2012

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Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophy.
Stijn Stroobants, Debora Gerlach, Frank Matthes, Dieter Hartmann, Jens Fogh, Ulrich Matzner

Hum Mol Genet· July 2011

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Transport of arylsulfatase A across the blood-brain barrier in vitro.
Frank Matthes, Philipp Wölte, Annika Böckenhoff, Sabine Hüwel, Mareike Schulz, Ulrich Matzner

J Biol Chem· May 2011

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Site-specific analysis of N-linked oligosaccharides of recombinant lysosomal arylsulfatase A produced in different cell lines.
Stephan Schröder, Frank Matthes, Pia Hyden, Claes Andersson, Jens Fogh, Ulrich Matzner

Glycobiology· February 2010

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Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy.
Ulrich Matzner, Renate Lüllmann-Rauch, Stijn Stroobants, Claes Andersson, Cecilia Weigelt

Mol Ther· April 2009

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Saposin B-dependent reconstitution of arylsulfatase A activity in vitro and in cell culture models of metachromatic leukodystrophy.
Ulrich Matzner, Bernadette Breiden, Günter Schwarzmann, Afshin Yaghootfam, Arvan L Fluharty

J Biol Chem· April 2009

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Non-inhibitory antibodies impede lysosomal storage reduction during enzyme replacement therapy of a lysosomal storage disease.
Ulrich Matzner, Frank Matthes, Cecilia Weigelt, Claes Andersson, Carl Eistrup

J Mol Med (Berl)· April 2008

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Induction of tolerance to human arylsulfatase A in a mouse model of metachromatic leukodystrophy.
Ulrich Matzner, Frank Matthes, Eva Herbst, Renate Lüllmann-Rauch, Zsuzsanna Callaerts-Vegh

Mol Med· December 2007

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Quantitative genotyping of single-nucleotide polymorphisms by allele-specific oligonucleotide hybridization on DNA microarrays.
Andreas M Rickert, Agim Ballvora, Ulrich Matzner, Manfred Klemm, Christiane Gebhardt

Biotechnol Appl Biochem· August 2005

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Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy.
Ulrich Matzner, Eva Herbst, Kerstin Khalaj Hedayati, Renate Lüllmann-Rauch, Carsten Wessig

Hum Mol Genet· May 2005

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Gene therapy of metachromatic leukodystrophy.
Ulrich Matzner, Volkmar Gieselmann

Expert Opin Biol Ther· January 2005

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Gene therapy: prospects for glycolipid storage diseases.
Volkmar Gieselmann, Ulrich Matzner, Diana Klein, Jan Eric Mansson, Rudi D'Hooge

Philos Trans R Soc Lond B Biol Sci· May 2003

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