Publications by authors named "Vancheswaran Gopalakrishnan"

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The human tumor microbiome is composed of tumor type-specific intracellular bacteria.
Deborah Nejman, Ilana Livyatan, Garold Fuks, Nancy Gavert, Yaara Zwang, Leore T Geller, Aviva Rotter-Maskowitz, Roi Weiser, Giuseppe Mallel, Elinor Gigi

Science· May 2020

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The microbiome, cancer, and cancer therapy.
Beth A Helmink, M A Wadud Khan, Amanda Hermann, Vancheswaran Gopalakrishnan, Jennifer A Wargo

Nat Med· March 2019

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Editor's Note: Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
Pei-Ling Chen, Whijae Roh, Alexandre Reuben, Zachary A Cooper, Christine N Spencer, Vancheswaran Gopalakrishnan

Cancer Discov· December 2025

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Epitope Conservation of AZD5148, a Broadly Neutralizing Anti-Toxin B Monoclonal Antibody, Among Diverse and Global Contemporary Clostridioides difficile Isolates.
Kelly Ann Mahool, Emily Nguyen, Victoria Godfrey, Ann Marie Stanley, Tyler Brady, Vancheswaran Gopalakrishnan

J Infect Dis· November 2025

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Lower Respiratory Tract Infections Following Respiratory Syncytial Virus Monoclonal Antibody Nirsevimab Immunization Versus Placebo: Analysis From a Phase 3 Randomized Clinical Trial (MELODY).
Doug Arbetter, Vancheswaran Gopalakrishnan, Anastasia A Aksyuk, Bahar Ahani, Yue Chang

Clin Infect Dis· October 2025

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A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.
Vancheswaran Gopalakrishnan, Chanchal Kumar, Ida Robertsen, Christopher Morehouse, Ben Sparklin

Mucosal Immunol· August 2025

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Preemptive optimization of a clinical antibody for broad neutralization of SARS-CoV-2 variants and robustness against viral escape.
Fangqiang Zhu, Saravanan Rajan, Conor F Hayes, Ka Yin Kwong, Andre R Goncalves, Vancheswaran Gopalakrishnan

Sci Adv· March 2025

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NTHi killing activity is reduced in COPD patients and is associated with a differential microbiome.
Vancheswaran Gopalakrishnan, Ben Sparklin, Jung Hwan Kim, Jerome Bouquet, Margaret Kehl

Respir Res· January 2025

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Oncologic Outcomes in Patients with Localized, Primary Head and Neck Synovial Sarcoma.
Riddhi R Patel, Vancheswaran Gopalakrishnan, Behrang Amini, Alexander J Lazar, Patrick P Lin

Cancers (Basel)· December 2024

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A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of in Patients with Bronchiectasis.
Merete B Long, Amy Gilmour, Margaret Kehl, David E Tabor, Ashley E Keller, Vancheswaran Gopalakrishnan

Am J Respir Crit Care Med· July 2024

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Analysis of SARS-CoV-2 Emergent Variants Following AZD7442 (Tixagevimab/Cilgavimab) for Early Outpatient Treatment of COVID-19 (TACKLE Trial).
Gustavo H Kijak, Bahar Ahani, Douglas Arbetter, Fernando Chuecos, Vancheswaran Gopalakrishnan

Infect Dis Ther· December 2023

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Neoadjuvant Durvalumab Alone or Combined with Novel Immuno-Oncology Agents in Resectable Lung Cancer: The Phase II NeoCOAST Platform Trial.
Tina Cascone, Gozde Kar, Jonathan D Spicer, Rosario García-Campelo, Walter Weder, Vancheswaran Gopalakrishnan

Cancer Discov· November 2023

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Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data.
Deidre Wilkins, Annefleur C Langedijk, Robert Jan Lebbink, Christopher Morehouse, Michael E Abram, Vancheswaran Gopalakrishnan

Lancet Infect Dis· July 2023

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Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Andrew W Hahn, Ashley V Menk, Dayana B Rivadeneira, Ryan C Augustin, Mingchu Xu, Vancheswaran Gopalakrishnan

Clin Cancer Res· January 2023

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Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1).
Chieko Michikawa, Vancheswaran Gopalakrishnan, Amani M Harrandah, Tatiana V Karpinets, Rekha Rani Garg

Neoplasia· September 2022

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StarGazer: A Hybrid Intelligence Platform for Drug Target Prioritization and Digital Drug Repositioning Using Streamlit.
Chiyun Lee, Junxia Lin, Andrzej Prokop, Vancheswaran Gopalakrishnan, Richard N Hanna

Front Genet· May 2022

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Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response.
Christine N Spencer, Jennifer L McQuade, Vancheswaran Gopalakrishnan, John A McCulloch, Marie Vetizou

Science· December 2021

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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
Miles C Andrews, Connie P M Duong, Vancheswaran Gopalakrishnan, Valerio Iebba, Wei-Shen Chen

Nat Med· August 2021

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Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen.
Vancheswaran Gopalakrishnan, Elizabeth Ashley Dozier, Matthew S Glover, Steven Novick, Michael Ford

Microorganisms· June 2021

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Antibiotics and Immunotherapy: Too Much of Anything is Bad!
Vancheswaran Gopalakrishnan, Bret R Sellman, Taylor S Cohen, Phillip A Dennis

Eur Urol· October 2020

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Gut Microbiome Signatures Are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia.
Jessica R Galloway-Peña, Yushu Shi, Christine B Peterson, Pranoti Sahasrabhojane, Vancheswaran Gopalakrishnan

Clin Infect Dis· June 2020

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B cells and tertiary lymphoid structures promote immunotherapy response.
Beth A Helmink, Sangeetha M Reddy, Jianjun Gao, Shaojun Zhang, Rafet Basar, Vancheswaran Gopalakrishnan

Nature· January 2020

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Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade.
Nicolas Jacquelot, Takahiro Yamazaki, Maria P Roberti, Connie P M Duong, Miles C Andrews, Vancheswaran Gopalakrishnan

Cell Res· October 2019

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Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer.
Sangeetha M Reddy, Alexandre Reuben, Souptik Barua, Hong Jiang, Shaojun Zhang, Vancheswaran Gopalakrishnan

Cancer Immunol Res· June 2019

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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Vancheswaran Gopalakrishnan

Cell· January 2019

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