Publications by authors named "Wang Keyun"

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Sequential denaturation and protein precipitation assay (SDPP) improves the sensitivity for ligand target identification at the proteome level.
Yanni Ma, Xiaolei Zhang, Longrun Shi, Jiayang Yan, Keyun Wang

Anal Chim Acta· December 2025

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A Detergent-Free Grinding Sample Preparation Method Dramatically Enhances PELSA for Mapping Integral Membrane Proteins-Ligand Interaction.
Ting Yu, Yan Wang, Yanan Li, Keyun Wang, Haiyang Zhu

Anal Chem· November 2025

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Decoding Arginine Dimethylation Isomers via pH-Tuned Reactivity with Methylglyoxal: A Chemical Approach for Functional Proteomics.
Jiayi Wang, Ye Liu, Qi Wang, Yanni Ma, Longrun Shi, Keyun Wang

J Am Chem Soc· November 2025

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Solvent-induced partial cellular fixation decodes proteome-wide drug targets and downstream pathways in living cells.
Ting Yu, Yan Wang, Keyun Wang, Zheng Fang, Haiyang Zhu

Nat Commun· November 2025

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PELSA-Decipher: A Software Tool for the Processing and Interpretation of Ligand-Protein Interaction Data Sets Acquired by PELSA.
Haiyang Zhu, Keyun Wang, Kejia Li, Zheng Fang, Jiahua Zhou

J Proteome Res· September 2025

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Probing ligand-induced local stability shifts: A sensitive approach to identify target proteins and binding sites at the proteomic scale.
Keyun Wang, Yanan Li, Yanni Ma, Mingliang Ye

Curr Opin Chem Biol· August 2025

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A peptide-centric local stability assay enables proteome-scale identification of the protein targets and binding regions of diverse ligands.
Kejia Li, Shijie Chen, Keyun Wang, Yan Wang, Lianji Xue

Nat Methods· February 2025

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A Chemoenzymatic Method Enables Global Enrichment and Characterization of Protein Arginine Methylation.
Jiayi Wang, Qi Wang, Jiahua Zhou, Yan Wang, Zhen Liu, Keyun Wang

Anal Chem· September 2024

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Correction: Starch branching enzymes as putative determinants of postharvest quality in horticultural crops.
Jingwei Yu, Keyun Wang, Diane M Beckles

BMC Plant Biol· August 2024

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Metabolic labeling based methylome profiling enables functional dissection of histidine methylation in C3H1 zinc fingers.
Keyun Wang, Li Zhang, Sirui Zhang, Ye Liu, Jiawei Mao

Nat Commun· August 2024

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Machine learning model for cardiovascular disease prediction in patients with chronic kidney disease.
He Zhu, Shen Qiao, Delong Zhao, Keyun Wang, Bin Wang

Front Endocrinol (Lausanne)· June 2024

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Validity and applicability of the global leadership initiative on malnutrition criteria in non-dialysis patients with chronic kidney disease.
Hui Huang, Qian Wang, Yayong Luo, Zhengchun Tang, Fang Liu, Keyun Wang

Front Nutr· February 2024

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Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge.
Amarendra Pegu, Sarah E Lovelace, Megan E DeMouth, Michelle D Cully, Daniel J Morris, Keyun Wang

Sci Transl Med· January 2024

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CDK11 requires a critical activator SAP30BP to regulate pre-mRNA splicing.
Changshou Wang, Lin Xu, Chen Du, Hao Yun, Keyun Wang

EMBO J· December 2023

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Hydrophobic Derivatization Strategy Facilitates Comprehensive Profiling of Protein Methylation.
Zhen Liu, Zheng Fang, Keyun Wang, Mingliang Ye

J Proteome Res· October 2023

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Integrated Protein Solubility Shift Assays for Comprehensive Drug Target Identification on a Proteome-Wide Scale.
Xiaolei Zhang, Chengfei Ruan, Yan Wang, Keyun Wang, Xiaoyan Liu

Anal Chem· September 2023

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Photoreactive Probe-Based Strategy Enables the Specific Identification of the Transient Substrates of Methyltransferase at the Proteome Scale.
Zhen Liu, Keyun Wang, Mingliang Ye

Anal Chem· August 2023

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Molecular basis for protein histidine N1-specific methylation of the "His-x-His" motifs by METTL9.
Wentao Zhao, Yang Zhou, Caiyi Li, Yucong Bi, Keyun Wang

Cell Insight· June 2023

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An antibody-free enrichment approach enabled by reductive glutaraldehydation for monomethyllysine proteome analysis.
Zhouxian Li, Qi Wang, Keyun Wang, Weibing Zhang, Mingliang Ye

Proteomics· February 2023

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The risk of acute and early HIV (AEH) infection among MSM with different behaviour trajectories: an open cohort study in Tianjin, China, 2011-2019.
Xiaomeng Wang, Tiantian Zhang, Qinxue Chang, Chun Wang, Keyun Wang

BMC Infect Dis· January 2023

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Highly effective identification of drug targets at the proteome level by pH-dependent protein precipitation.
Xiaolei Zhang, Keyun Wang, Sijin Wu, Chengfei Ruan, Kejia Li

Chem Sci· November 2022

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Prostate Cancer Risk Prediction and Online Calculation Based on Machine Learning Algorithm.
Chun Wang, Qin-Xue Chang, Xiao-Meng Wang, Ke-Yun Wang, He Wang

Chin Med Sci J· September 2022

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Effects of daily mean temperature and other meteorological variables on bacillary dysentery in Beijing-Tianjin-Hebei region, China.
Qinxue Chang, Keyun Wang, Honglu Zhang, Changping Li, Yong Wang

Environ Health Prev Med· March 2022

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Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys.
Amarendra Pegu, Ling Xu, Megan E DeMouth, Giulia Fabozzi, Kylie March, Keyun Wang

Cell Rep· January 2022

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Starch branching enzymes as putative determinants of postharvest quality in horticultural crops.
Jingwei Yu, Keyun Wang, Diane M Beckles

BMC Plant Biol· October 2021

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