Publications by authors named "YangXin Fu"

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Porous microscaffold enables spontaneous hematopoietic cell differentiation and continuous macrophage production from hPSCs for therapy.
Peiliang Wang, Hui Qiu, Xia Chen, Wenjing Li, Tianjie Li, Yangxin Fu

Biomaterials· March 2026

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Establishment and characterization of preclinical models of human gynecologic tract carcinosarcomas demonstrates targetable FGFR1 alterations.
Nelson K Y Wong, Marta Llaurado Fernandez, Hannah Kim, Pooja Praveen Kumar, DuPreez Smith, Yangxin Fu

Transl Oncol· January 2026

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Tumors with microsatellite instability upregulate TREX1 to escape antitumor immunity.
Yan Xu, Zheqi Zhou, Wenzheng Chen, Fei Du, Sanling Huang, Chunfu Xiao, Yang-Xin Fu

J Exp Med· December 2025

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CARD9-dependent macrophage plasticity regulates effective fungal clearance.
Lu Zhang, Zhichun Tang, Yi Zhang, Wenjie Liu, Haitao Jiang, Yang-Xin Fu

J Clin Invest· December 2025

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Anti-PD-L1-IFN-α-adjuvanted HBsAg vaccine overcomes HBV immune tolerance through targeting both DCs and macrophages.
Chao-Yang Meng, Yong Liang, Longxin Xu, Hongjia Li, Jingya Guo, Yang-Xin Fu

JCI Insight· December 2025

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Tumor-targeted delivery of CXCL10 by mesenchymal stromal cells potentiates adoptive T cell therapy to treat solid tumors.
Jeong Ho Yoon, Gyu-Bum Yeon, Hojae Lee, Hyunseo An, Jiwon Oh, Yang-Xin Fu

Biomed Pharmacother· November 2025

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Correction: Suppression of local type I interferon by gut microbiota-derived butyrate impairs antitumor effects of ionizing radiation.
Kaiting Yang, Yuzhu Hou, Yuan Zhang, Hua Liang, Anukriti Sharma, Yang-Xin Fu

J Exp Med· October 2025

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A next-generation anti-CTLA-4 probody mitigates toxicity and enhances anti-tumor immunity in mice.
Weian Cao, Junfan Chen, Yutong Fu, Haitao Jiang, Yu Gao, Yang-Xin Fu

Nat Commun· October 2025

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Smohaze-Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non-Small Cell Lung Cancer.
Xue-Yan Shi, Yu-Ke Shen, Meng-Yao Lv, Yu Sun, Yong-Fang Lin, Yang-Xin Fu

Adv Sci (Weinh)· October 2025

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Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control.
Kun Peng, Xiaoxue Zhao, Hongjian Li, Yang-Xin Fu, Yong Liang

J Exp Med· September 2025

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Dual targeting OX40 and IL-2 receptor enhances antitumor activity through tumor-infiltrating Treg depletion and CD8 T-cell proliferation.
Shuaishuai Cao, Zhichen Sun, Wenbo Hu, Diyuan Xue, Zuming Yang, Yang-Xin Fu

J Immunother Cancer· September 2025

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Eliciting antitumor immunity via therapeutic cancer vaccines.
Kun Peng, Xiaoxue Zhao, Yang-Xin Fu, Yong Liang

Cell Mol Immunol· August 2025

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Orchestrating intratumoral DC-T cell immunity for enhanced tumor control via radiotherapy-activated TLR7/8 prodrugs in mice.
Xiaozhe Yin, Zexuan Ding, Li Yu, Xuhao Zhang, Yu Gao, Yang-Xin Fu

Nat Commun· July 2025

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Single atom engineering for radiotherapy-activated immune agonist prodrugs.
Zexuan Ding, Xiaozhe Yin, Yuedan Zheng, Yiyan Li, Huanhuan Ge, Yang-Xin Fu

Nat Commun· July 2025

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Concurrent intratumoural T cell depletion and CD8 T cell expansion via a cleavable anti-4-1BB-interleukin-15 fusion protein.
Yueqi Cai, Zilong Han, Jiao Shen, Zhuangzhi Zou, Jingya Guo, Yang-Xin Fu

Nat Biomed Eng· June 2025

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TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8T cell exhaustion.
Xuhao Zhang, Yu Gao, Huiping Liao, Wenyan Wang, Zaili Yang, Yang-Xin Fu

Nat Commun· June 2025

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ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling.
Hongkai Xu, Yibo Wang, Wenyan Wang, Yang-Xin Fu, Ju Qiu

Sci Immunol· May 2025

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Engineering cytokines for tumor-targeting and selective T cell activation.
Kun Peng, Yang-Xin Fu, Yong Liang

Trends Mol Med· April 2025

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ILC3s regulate the gut microbiota via host intestinal galactosylation to limit pathogen infection in mice.
Wenyan Wang, Na Li, Hongkai Xu, Siting Wei, Yiping Li, Yang-Xin Fu

Nat Microbiol· March 2025

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Potentiating anti-tumor immunity by re-engaging immune synapse molecules.
Xindi Zhou, Tian Xu, Changhe Li, Yufeng He, Yuanzhi Hu, Yangxin Fu

Cell Rep Med· March 2025

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Sequential intranasal booster triggers class switching from intramuscularly primed IgG to mucosal IgA against SARS-CoV-2.
Yifan Lin, Xuejiao Liao, Xuezhi Cao, Zhaoyong Zhang, Xiuye Wang, Furong Qi, Yang-Xin Fu

J Clin Invest· January 2025

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TCR-mimicking STAR conveys superior sensitivity over CAR in targeting tumors with low-density neoantigens.
Daosheng Huang, Yi Li, Wei Rui, Keyong Sun, Zhixiao Zhou, Yang-Xin Fu

Cell Rep· November 2024

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Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth.
Xuxiang Wang, Tengjiang Zhang, Bingxin Zheng, Youxue Lu, Yong Liang, Yang-Xin Fu

Nat Cell Biol· September 2024

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Metabolic reprograming mediated by tumor cell-intrinsic type I IFN signaling is required for CD47-SIRPα blockade efficacy.
Hang Zhou, Wenjun Wang, Hairong Xu, Yong Liang, Jiyu Ding, Yang-Xin Fu

Nat Commun· July 2024

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Targeted proteomics of plasma extracellular vesicles uncovers MUC1 as combinatorial biomarker for the early detection of high-grade serous ovarian cancer.
Tyler T Cooper, Dylan Z Dieters-Castator, Jiahui Liu, Gabrielle M Siegers, Desmond Pink, Yangxin Fu

J Ovarian Res· July 2024

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