Publications by authors named "You Cheng Hseu"

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The skin hydration and anti-ageing benefits of Ectoine, achieved through enhanced Src-ERK-mediated HAS-2 and JNK-driven AQP-3 expression in human keratinocytes, along with the inhibition of MMP-1-induced collagen-I degradation in human fibroblasts, both with and without UVB irradiation.
Po-Yuan Wu, Jhih-Hsuan Hseu, Ying-Ru Chen, Sudhir Pandey, Siang-Jyun Chen, You-Cheng Hseu

Int J Cosmet Sci· October 2025

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PDCD2L overexpression represents an unfavorable prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer.
Ding-Ping Sun, Chun-Chao Chang, Hsuan-Yi Huang, Nai-Weng Kang, You-Cheng Hseu

Cancer Biomark· September 2025

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Dihydromikanolide Inhibits ROS-Mediated NLRP3 Inflammation via Antioxidant Nrf2 Activation and Mitophagy Induction in LPS/ATP-Stimulated Macrophages.
You-Cheng Hseu, Yu-Fang Tseng, Jhih Ke-Hseu, Sudhir Pandey, Siang-Jyun Chen, Jhih-Hsuan Hseu

J Cell Mol Med· August 2025

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The in vitro and in vivo skin-whitening activity of Ectoine through enhanced autophagy in melanocytes and keratinocytes and zebrafish model.
Wei-Chen Jane, Siang-Jyun Chen, Jhih-Hsuan Hseu, Xuan-Zao Chen, Sudhir Pandey, You-Cheng Hseu

Biofactors· May 2025

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Naringin Induces ROS-Stimulated G Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells.
Chan-Hung Chen, Ni Tien, Chun-Hsu Yao, Siang-Jyun Chen, Da-Tian Bau, You-Cheng Hseu

Environ Toxicol· November 2024

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Coenzyme Q inhibited the NLRP3 inflammasome, metastasis/EMT, and Warburg effect by suppressing hypoxia-induced HIF-1α expression in HNSCC cells.
Hsin-Ling Yang, Che-Wei Chang, Chithravel Vadivalagan, Sudhir Pandey, Siang-Jyun Chen, Jhih-Hsuan Hseu, You-Cheng Hseu

Int J Biol Sci· June 2024

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The in vitro and in vivo depigmentation activity of coenzyme Q, a major quinone derivative from Antrodia camphorata, through autophagy induction in human melanocytes and keratinocytes.
You-Cheng Hseu, Jou-Tsen Yeh, Chithravel Vadivalagan, Siang-Jyun Chen, Yugandhar Vudhya Gowrisankar, Jhih-Hsuan Hseu

Cell Commun Signal· February 2024

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Antrodia salmonea suppresses epithelial-mesenchymal transition/metastasis and Warburg effects by inhibiting Twist and HIF-1α expression in Twist-overexpressing head and neck squamous cell carcinoma cells.
Jhih-Hsuan Hseu, Yi-An Lin, Sudhir Pandey, Chithravel Vadivalagan, Asif Ali, You-Cheng Hseu

J Ethnopharmacol· January 2024

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Tranexamic acid improves psoriasis-like skin inflammation: Evidence from in vivo and in vitro studies.
Jhih-Hsuan Hseu, Chon-I Chan, Chithravel Vadivalagan, Siang-Jyun Chen, Hung-Rong Yen, You-Cheng Hseu

Biomed Pharmacother· October 2023

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Antrodia camphorata and coenzyme Q , a novel quinone derivative of Antrodia camphorata, impede HIF-1α and epithelial-mesenchymal transition/metastasis in human glioblastoma cells.
Hsin-Ling Yang, Yao-Hsien Chang, Sudhir Pandey, Asif Ali Bhat, Chithravel Vadivalagan, You-Cheng Hseu

Environ Toxicol· July 2023

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Coenzyme Q defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells.
Hsin-Ling Yang, Ping-Yu Lin, Chithravel Vadivalagan, Yi-An Lin, Kai-Yuan Lin, You-Cheng Hseu

Arch Toxicol· April 2023

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In vitro and in vivo anti-tumor activity of Coenzyme Q against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy/apoptosis induction.
Hsin-Ling Yang, Li-Wen Chiu, Yi-An Lin, Sudhir Pandey, Chithravel Vadivalagan, You-Cheng Hseu

Toxicol Appl Pharmacol· April 2023

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In vitro and in vivo anti-tumor activity of Antrodia salmonea against twist-overexpressing HNSCC cells: Induction of ROS-mediated autophagic and apoptotic cell death.
Hsin-Ling Yang, Yi-An Lin, Sudhir Pandey, Jiunn-Wang Liao, Tzong-Der Way, You-Cheng Hseu

Food Chem Toxicol· February 2023

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The in vitro and in vivo anticancer activities of Antrodia salmonea through inhibition of metastasis and induction of ROS-mediated apoptotic and autophagic cell death in human glioblastoma cells.
Yi-Pin Lin, You-Cheng Hseu, Varadharajan Thiyagarajan, Chithravel Vadivalagan, Sudhir Pandey

Biomed Pharmacother· February 2023

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The Warburg effect in osteoporosis: Cellular signaling and epigenetic regulation of energy metabolic events to targeting the osteocalcin for phenotypic alteration.
Chithravel Vadivalagan, Anand Krishnan, Siang-Jyun Chen, You-Cheng Hseu, Sathish Muthu

Cell Signal· December 2022

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Coenzyme Q Inhibits NLRP3 Inflammasome Activation through Mitophagy Induction in LPS/ATP-Stimulated Macrophages.
You-Cheng Hseu, Yu-Fang Tseng, Sudhir Pandey, Sirjana Shrestha, Kai-Yuan Lin

Oxid Med Cell Longev· March 2022

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Calycosin, a Common Dietary Isoflavonoid, Suppresses Melanogenesis through the Downregulation of PKA/CREB and p38 MAPK Signaling Pathways.
Kun-Chang Wu, You-Cheng Hseu, Yu-Ching Shih, Govindan Sivakumar, Jyun-Ting Syu

Int J Mol Sci· January 2022

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GRK3 as a Prognosis Biomarker in Gastric Cancer.
Chia-Lang Fang, Yu-Feng Tian, Shiau-Shiuan Lin, Shih-Ting Hung, You-Cheng Hseu

J Cancer· January 2022

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Bisdemethoxycurcumin Promotes Apoptosis and Inhibits the Epithelial-Mesenchymal Transition through the Inhibition of the G-Protein-Coupled Receptor 161/Mammalian Target of Rapamycin Signaling Pathway in Triple Negative Breast Cancer Cells.
Chun-Hung Chou, Hao-Kuang Wang, Ying-Chao Lin, Dai-Hua Tsai, Meng-Tien Lu, You-Cheng Hseu

J Agric Food Chem· December 2021

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Coenzyme Q, a novel quinone derivative of Antrodia camphorata, induces ROS-mediated cytotoxic autophagy and apoptosis against human glioblastoma cells in vitro and in vivo.
Hsin-Ling Yang, Chia-Hsuan Tsai, Sirjana Shrestha, Chuan-Chen Lee, Jiunn-Wang Liao, You-Cheng Hseu

Food Chem Toxicol· September 2021

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The anti-melanogenic effects of 3-O-ethyl ascorbic acid via Nrf2-mediated α-MSH inhibition in UVA-irradiated keratinocytes and autophagy induction in melanocytes.
Siang-Jyun Chen, You-Cheng Hseu, Yugandhar Vudhya Gowrisankar, Yi-Ting Chung, Yan-Zhen Zhang

Free Radic Biol Med· September 2021

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The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-mediated antioxidant pathways.
You-Cheng Hseu, Yugandhar Vudhya Gowrisankar, Li-Wei Wang, Yan-Zhen Zhang, Xuan-Zao Chen

Redox Biol· August 2021

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A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway.
Ding-Ping Sun, Yu-Feng Tian, Chih-Chan Lin, Shih-Ting Hung, Yih-Huei Uen, You-Cheng Hseu

Am J Cancer Res· June 2021

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induces apoptosis and enhances cytoprotective autophagy in colon cancer cells.
Hsin-Ling Yang, Hui-Wen Liu, Sirjana Shrestha, Varadharajan Thiyagarajan, Hui-Chi Huang, You-Cheng Hseu

Aging (Albany NY)· May 2021

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The anti-melanogenic effects of ellagic acid through induction of autophagy in melanocytes and suppression of UVA-activated α-MSH pathways via Nrf2 activation in keratinocytes.
Hsin-Ling Yang, Chia-Pei Lin, Yugandhar Vudhya Gowrisankar, Pei-Jane Huang, Wan-Lin Chang, You-Cheng Hseu

Biochem Pharmacol· March 2021

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