Publications by authors named "Z Debyser"

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BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription.
Eline Pellaers, Julie Janssens, Lore Wils, Alexe Denis, Anayat Bhat, Zeger Debyser

Nat Commun· May 2025

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Role of LEDGF/p75 (PSIP1) in oncogenesis. Insights in molecular mechanism and therapeutic potential.
Muluembet Akele, Matteo Iervolino, Siska Van Belle, Frauke Christ, Zeger Debyser

Biochim Biophys Acta Rev Cancer· February 2025

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LEDGF interacts with the NID domain of MeCP2 and modulates MeCP2 condensates.
Saskia Lesire, Rodrigo Lata, Yannick Hoogvliets, Kune Herrebosch, Paulien Van De Velde, Zeger Debyser

Structure· January 2025

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Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.
Thibault Vantieghem, Nayyar A Aslam, Evgenii M Osipov, Muluembet Akele, Siska Van Belle, Zeger Debyser

Eur J Med Chem· December 2024

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A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.
Lisa Demoen, Filip Matthijssens, Lindy Reunes, Bruno Palhais, Béatrice Lintermans, Zeger Debyser

Sci Adv· November 2024

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