Endocr Rev February 2000 PMID 10696570

How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.

R M Sapolsky, L M Romero, A U Munck

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Mentions

21
Peak: 2 in Sep 2025
across 5 sources since Feb 2022

Extended reach

13,064
potential audience

Total likes

33

Video views

2,481

Mentions per month

Feb 2022 – Oct 2025

Where it's discussed

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  • YouTube5 videos
  • Blogs3 articles
  • X / Twitter2 posts
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AI synopsis

What people are saying

Discussions highlight the multifaceted roles of glucocorticoids, with examples like references to their effects on cardiovascular and immune systems, emphasizing the article's relevance. The tone varies from supportive to inquisitive, demonstrating both appreciation of the research and curiosity about its applications, which influences the moderate engagement and perceived impact.

AgreementModerate agreement

Most discussions support the idea that glucocorticoids have complex and significant roles in stress responses, aligning with the article's comprehensive review.

InterestHigh interest

Posts show high curiosity and engagement, with many referencing specific physiological effects and the broader implications of the research.

EngagementModerate engagement

Participants delve into detailed critiques and reflections on the physiological mechanisms, indicating active engagement.

ImpactModerate impact

The overall tone suggests that this research influences views on stress management and hormonal function, though the discourse is mostly academic rather than directly actionable.

Abstract in brief

  • Glucocorticoids (GCs) are hormones released during stress, but scientists still debate whether their main role is to help activate, suppress, or prepare the body for stress responses.
  • The article reviews recent research to determine when GCs enable ongoing stress responses, suppress them to prevent overreaction, or prepare the body for future stress, with different effects observed in areas like heart function, immunity, metabolism, and reproduction.
  • Overall, GCs have diverse actions that vary depending on the specific physiological process, and the article tries to integrate these different roles into a comprehensive understanding of how GCs coordinate stress responses.

Top posts

Most liked on X and Bluesky
Juliana
@Dubious_Angel · X

@OnlyPianos one set of 'stress hormones' produced by the adrenal glands, secreted in response to stressful situations. I was just backing up your point, sardonically. https://t.co/vG0W8Xha8J

Feb 20, 2022 · 1 like · 10,572 followers View post →
Kohei Fuseda
@k_fuseda · X

コルチゾールの勉強に読んだ論文が面白かった。心臓血管系との関わりや、標的期間に作用する時間とか、コルチゾール測らなくても知っておくべきことがたくさん書かれてた。 https://t.co/Up0ojlyf9q

Nov 1, 2024 · 13 followers View post →

All mentions

Kohei Fuseda
@k_fuseda · X

コルチゾールの勉強に読んだ論文が面白かった。心臓血管系との関わりや、標的期間に作用する時間とか、コルチゾール測らなくても知っておくべきことがたくさん書かれてた。 https://t.co/Up0ojlyf9q

Nov 1, 2024 · 13 followers View post →
Juliana
@Dubious_Angel · X

@OnlyPianos one set of 'stress hormones' produced by the adrenal glands, secreted in response to stressful situations. I was just backing up your point, sardonically. https://t.co/vG0W8Xha8J

Feb 20, 2022 · 1 like · 10,572 followers View post →