April 2000 PMID 10770979

Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. Polyp Prevention Trial Study Group.

A Schatzkin, E Lanza, D Corle, P Lance, F Iber, B Caan, M Shike, J Weissfeld, R Burt, M R Cooper, J W Kikendall, J Cahill

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Mentions

58
Peak: 30 in May 2019
across 4 sources since Feb 2019

Extended reach

417,120
potential audience

Total likes

5,200

Video views

212,189

Mentions per month

Feb 2019 – May 2025

Where it's discussed

  • X / Twitter48 posts
  • Facebook5 posts
  • YouTube3 videos
  • News2 articles

AI synopsis

What people are saying

The discussions reflect a balanced mix of acceptance and skepticism, with posts like '@bryan_johnson Not supported by RCT evidence' indicating disagreement, while others mention clinical trials and epidemiological studies, exemplifying engagement in evaluating the study's validity and impact.

AgreementNeither agree nor disagree

Posts are mixed, with some acknowledging the study's findings and others questioning its conclusions or methodology.

InterestModerate interest

Discussions show moderate curiosity, especially around the conflicting beliefs about diet and cancer prevention.

EngagementModerate engagement

Posts reference specific aspects of the study, such as randomized controlled trials and controversies, showing moderate reflection.

ImpactNeutral impact

Overall, discussions highlight the importance of scientific evidence in diet recommendations but do not suggest a transformative effect on dietary guidelines.

Abstract in brief

  • The study tested whether a diet low in fat and high in fiber, fruits, and vegetables could reduce the recurrence of colorectal adenomas, which are precursors to colon cancer, but found no significant effect.
  • Over about four years, nearly all participants completed the study, and similar percentages in both groups experienced recurrent adenomas, with no statistically significant difference between the intervention and control groups.
  • The results indicated that adopting a low-fat, high-fiber diet does not significantly decrease the risk of developing new or larger, more advanced adenomas in individuals previously treated for colorectal adenomas.]

Top posts

Most liked on X and Bluesky
George D. Henderson
@puddleg · X

A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer was diagnosed in 14 subjects after randomization (10 in the intervention group and 4 in the control group); RR 2.5 (P=0.19). https://t.co/0oqCDNGjBY

May 28, 2019 · 63 likes · 30 shares · 7,371 followers View post →
Tucker Goodrich
@TuckerGoodrich · X

"Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrence of colorectal adenomas." https://t.co/Hdbq8cbNrI

Jan 17, 2020 · 9 likes · 1 share · 28,255 followers View post →
Manni Mohyuddin
@ManniMD1 · X

@VPrasadMDMPH A trial was done.. (not the exact question- but speaks to how simplistic thinking often doesnt translate well in randomized trials) https://t.co/82ARvkbdvo

Jul 7, 2024 · 4 likes · 12,991 followers View post →
George D. Henderson
@puddleg · X

@CarbAppropriate @NanciGuestRDPhD @mackinprof If you only read e[pi papers from the USA, you might hypothesize that reducing meat and increasing wholegrains will reduce risk for cancer and CVD. Then what do you do? Test the hypothesis with an experiment. . For cancer: https://t.co/0oqCDNGjBY For all: https://t.co/rk9GhQ6diW

Jun 17, 2019 · 4 likes · 7,371 followers View post →
Manni Mohyuddin
@ManniMD1 · X

Low fat high fiber diet did not reduce recurrence of colorectal adenomas https://t.co/2tZgtLe2wF

Dec 31, 2023 · 3 likes · 12,991 followers View post →
Tim Rees
@NutritionalThe3 · X

'Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrence of colorectal adenomas.' #RCTSONLY https://t.co/4cErFVXmON

Jun 21, 2021 · 3 likes · 2 shares · 4,928 followers View post →

All mentions

Viper | Citizen #2086 | ▚▘▚▘▚▘
@KingViperius · X

@bryan_johnson Not supported by RCT evidence Brian. https://t.co/j4g2NOlHix https://t.co/SV5eoiEjFm

Jan 15, 2025 · 533 followers View post →
Manni Mohyuddin
@ManniMD1 · X

@VPrasadMDMPH A trial was done.. (not the exact question- but speaks to how simplistic thinking often doesnt translate well in randomized trials) https://t.co/82ARvkbdvo

Jul 7, 2024 · 4 likes · 12,991 followers View post →
Manni Mohyuddin
@ManniMD1 · X

Low fat high fiber diet did not reduce recurrence of colorectal adenomas https://t.co/2tZgtLe2wF

Dec 31, 2023 · 3 likes · 12,991 followers View post →
MonCarnivore
@moncarnivore · X

Et les supposés bienfaits des fibres (légumes et fruits)

Jul 12, 2023 · 103 followers View post →
Krzysiek Miszewski
@MISZEWSKIKRIS · X

@HalikRafa @rieske_piotr I jeszcze jeden link do badania klinicznego: https://t.co/6r5FyXIWZc

Feb 20, 2023 · 580 followers View post →
Krzysiek Miszewski
@MISZEWSKIKRIS · X

@HalikRafa @rieske_piotr Poniżej podaję linki do 2 badań klinicznych (dużo większa wiarygodność wzgl. epidemiologicznych) stojących w sprzeczności z przedstawionymi przez Pana tezami. https://t.co/6r5FyXIWZc https://t.co/qgCsWlF3Np

Feb 20, 2023 · 580 followers View post →
Maurício Lima
@dj_surfista · X

A adoção de uma dieta pobre em gorduras e rica em fibras, frutas e vegetais não influencia no risco de recorrência de adenomas colorretais. #colorectalcancer #cancer #Oncologia #Oncology https://t.co/DCKKaqGZ6o

Jun 22, 2021 · 741 followers View post →
Sunset HQ
@SunsetHQBC · X

RT @NutritionalThe3: 'Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrenc…

Jun 21, 2021 · 2 shares · 15 followers View post →
Lauren Renée
@NaultyByNature · X

RT @NutritionalThe3: 'Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrenc…

Jun 21, 2021 · 2 shares · 685 followers View post →
Tim Rees
@NutritionalThe3 · X

'Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrence of colorectal adenomas.' #RCTSONLY https://t.co/4cErFVXmON

Jun 21, 2021 · 3 likes · 2 shares · 4,928 followers View post →
Bart Jankowski
@bartjankowski82 · X

@KenDBerryMD 1-https://t.co/hVXDlRA0jQ 2- https://t.co/gqGAylZk4C 3- https://t.co/5juzPGIutg 4-https://t.co/ZeesKqP00P 5-https://t.co/E9Rmam62cJ 6- https://t.co/E9Rmam62cJ 7- https://t.co/WoBV4FmPru 8- https://t.co/b5OvuhM1Xa 9- https://t.co/UhORq9RSgf 10- https://t.co/4PYCSx8pfM

Sep 13, 2020 · 2 likes · 48 followers View post →
Jing
@CaATiER_Chop_ER · X

RT @TuckerGoodrich: "Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrence…

Jan 17, 2020 · 1 share · 321 followers View post →
Tucker Goodrich
@TuckerGoodrich · X

"Adopting a diet that is low in fat and high in fiber, fruits, and vegetables does not influence the risk of recurrence of colorectal adenomas." https://t.co/Hdbq8cbNrI

Jan 17, 2020 · 9 likes · 1 share · 28,255 followers View post →
OTTER BUTTER
@StarbustingO · X

@BeyondTheDon @ge_kaitlyn Well if so, then please note that that study has many controversies around it, like how they got the data and how it's an observational study. I have a something for you https://t.co/cjNmHOqQ5b This is a good study where they tested a low fat diet.

Nov 27, 2019 · 277 followers View post →
George McWhirter
@GeorgeMcWhirter · X

@ZahcM Yes: https://t.co/ULeBe80iCd So what can be done?

Jul 16, 2019 · 76 followers View post →
George D. Henderson
@puddleg · X

@CarbAppropriate @NanciGuestRDPhD @mackinprof If you only read e[pi papers from the USA, you might hypothesize that reducing meat and increasing wholegrains will reduce risk for cancer and CVD. Then what do you do? Test the hypothesis with an experiment. . For cancer: https://t.co/0oqCDNGjBY For all: https://t.co/rk9GhQ6diW

Jun 17, 2019 · 4 likes · 7,371 followers View post →
George D. Henderson
@puddleg · X

@saenger_david @Travis_Statham @HarvardChanSPH @Harvard Here's where they tested the hypothesis. https://t.co/0oqCDNGjBY

Jun 13, 2019 · 1 like · 7,371 followers View post →
Daniel G Ascenço, M.D.
@AscencoDaniel · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 30, 2019 · 30 shares · 49 followers View post →
João Martins
@joaomartins2710 · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 30, 2019 · 30 shares · 296 followers View post →
Don Tidwell
@tidwell_don · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 3,491 followers View post →
FIAT bear
@abl_trader · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 1,817 followers View post →
Cliff Harvey PhD
@CarbAppropriate · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 1,787 followers View post →
Nick Papageorge
@NickPapageorge1 · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 2,029 followers View post →
Vet Goed
@VetGoed · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 388 followers View post →
Beatriz Yumi
@Beatrizzyumi · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 4 followers View post →
Cassie
@Cassign · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 956 followers View post →
Jose C Souto, MD
@jcsouto · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 14,604 followers View post →
Solomon Asare
@SolomonKAsare · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 395 followers View post →
European Society of Preventive Medicine
@ESPM_org · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 2,064 followers View post →
Captain Miller
@_CHOTUS · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 512 followers View post →
Ted Clark
@tedrsa · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 183 followers View post →
AKA_Sadrien
@AKA_Sadrien · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 29, 2019 · 30 shares · 792 followers View post →
Steven M. Weil
@smweilhermes · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 306 followers View post →
Leland Sandfort
@leland_sandfort · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 1,031 followers View post →
Prof Dr Helen Batty
@hbelfry · X

Toronto men on usual diet in RCT may have been protected from colon cancer risk? Lack of Effect of a Low-Fat, High-Fiber Diet on the Recurrence of Colorectal Adenomas | NEJM https://t.co/H1oIJ9Y9Ly

May 28, 2019 · 1,313 followers View post →
Ari Melmed
@AZMelmed · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 190 followers View post →
Ana Cláudia
@Anawsantos · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 353 followers View post →
catoraño
@catorano · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 4,073 followers View post →
Philip Chaipis, MD FACS
@chaipis · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 139 followers View post →
David Diamond
@LDLSkeptic · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 44,475 followers View post →
David Wyant
@wyadvd · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 2,686 followers View post →
eleanorina
@_eleanorina · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 3,167 followers View post →
Amanda ZZ - Atkins
@AmandaZZ100 · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 4,723 followers View post →
laili
@laili_lai · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 67 followers View post →
DiscoStew
@DiscoStew66 · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 10,771 followers View post →
Mad
@MadPharmacist1 · X

RT @puddleg: A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer w…

May 28, 2019 · 30 shares · 6,494 followers View post →
George D. Henderson
@puddleg · X

A trial of reduced red meat and fat, increased whole grain fibre for colorectal cancer prevention, n=1905. Colorectal cancer was diagnosed in 14 subjects after randomization (10 in the intervention group and 4 in the control group); RR 2.5 (P=0.19). https://t.co/0oqCDNGjBY

May 28, 2019 · 63 likes · 30 shares · 7,371 followers View post →
TAOisTheKey
@TaoIsTheKey · X

Reducing red meat, reducing fat, and increasing fiber and vegetables in the diets of over 2000 study participants made absolutely no difference in their colon cancer risk. https://t.co/GMpmX1YrIX https://t.co/GMpmX1YrIX

Feb 13, 2019 · 8,784 followers View post →