Am J Psychiatry January 2002 PMID 11772700

Changes in brain function of depressed subjects during treatment with placebo.

Andrew F Leuchter, Ian A Cook, Elise A Witte, Melinda Morgan, Michelle Abrams

Mentions

28
Peak: 1 in Jul 2017
across 5 sources since Jul 2017

Extended reach

17,826
potential audience

Total likes

444

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Jul 2017 – Mar 2025

Where it's discussed

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AI synopsis

What people are saying

The comments emphasize how expectancy or belief may trigger physiological processes similar to actual treatment responses, using phrases like 'can produce similar benefits' and referencing the study to support this idea. The tone is somewhat speculative and general, reflecting typical social discussions that acknowledge the significance without delving into detailed scientific analysis.

AgreementModerate agreement

The discussion reflects general agreement with the idea that physiological responses can be triggered by expectations or belief in treatment, aligning with the research's focus on brain changes during placebo responses.

InterestModerate interest

Posts show moderate interest, especially in how physiological processes and placebo effects relate, but lack in-depth analysis or curiosity about detailed mechanisms.

EngagementNeutral engagement

Comments are somewhat superficial, mainly referencing the study title and general concepts without deep analysis or personal insights.

ImpactModerate impact

The discussion hints at potential implications for understanding placebo effects in depression treatment, indicating moderate perceived relevance but limited immediate impact.

Abstract in brief

  • The study explored how brain activity differs in depressed patients who respond to either medication or placebo, finding that placebo responders show early increases in prefrontal cordance, a measure related to brain perfusion, unlike medication responders.
  • Both treatment groups showed no significant differences before treatment, but during the study, placebo responders exhibited specific brain changes not seen in medication responders or nonresponders, indicating different underlying brain mechanisms.
  • These results suggest that changes in brain function, especially in prefrontal cordance, could potentially help distinguish between patients who are responding to placebo versus actual medication, which might improve treatment approaches.]

Top posts

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Psikoloji Arşiv
@psikolojiarsiv · X

Olumlu sonucun inancı veya beklentisi aynı fizyolojik süreçleri tetikleyebilir ve bu yüzden, suni bir maddedin yarattığı aynı yararları üretebilir. İlgili araştırma: Changes in Brain Function of Depressed Subjects During Treatment With Placebo #Antidepresan #Psikoloji #Makale

May 3, 2020 · 3,345 followers View post →

All mentions

Psikoloji Arşiv
@psikolojiarsiv · X

Olumlu sonucun inancı veya beklentisi aynı fizyolojik süreçleri tetikleyebilir ve bu yüzden, suni bir maddedin yarattığı aynı yararları üretebilir. İlgili araştırma: Changes in Brain Function of Depressed Subjects During Treatment With Placebo #Antidepresan #Psikoloji #Makale

May 3, 2020 · 3,345 followers View post →