March 2002 PMID 11832356

Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.

T A Trappe, F White, C P Lambert, D Cesar, M Hellerstein, W J Evans

Mentions

45
Peak: 4 in Mar 2025
across 6 sources since Dec 2020

Extended reach

1,077,490
potential audience

Total likes

22,684

Video views

1,060,289

Mentions per month

Dec 2020 – Oct 2025

Where it's discussed

  • News17 articles
  • Facebook10 posts
  • X / Twitter7 posts
  • YouTube6 videos
  • Reddit3 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect cautious acknowledgment of the study's significance, with phrases like 'interesting' and references to specific mechanisms, which indicate a moderate level of engagement and implications for how analgesics could affect muscle recovery after exercise.

AgreementModerate agreement

Most comments acknowledge the study's findings, with some emphasizing the importance of the results as seen in statements like 'also interesting' and highlighting that common analgesics may hinder muscle recovery.

InterestModerate interest

The discussions show moderate curiosity, focusing on the implications of the research for exercise routines and recovery strategies, though not overwhelmingly enthusiastic.

EngagementModerate engagement

Participants reference specific findings, such as suppression of muscle protein synthesis, and discuss the broader impacts, indicating a thoughtful level of engagement.

ImpactModerate impact

There is recognition that these findings may alter perceptions around over-the-counter pain medications after workouts, suggesting potential influence on training and recovery practices.

Abstract in brief

  • Both ibuprofen and acetaminophen, when taken in over-the-counter doses after high-intensity eccentric exercise, do not increase muscle protein synthesis; in fact, they seem to suppress it.
  • The study found that in the placebo group, muscle protein synthesis significantly increased 24 hours post-exercise, but this increase was not observed in groups taking either drug.
  • Neither medication affected overall protein breakdown or muscle soreness, suggesting these common analgesics might influence muscle protein metabolism through a similar mechanism, potentially impacting muscle recovery.]

Top posts

Most liked on X and Bluesky
Bas
@BasB3 · X

@Jozo_Grgic Also interesting: https://t.co/ZPZ3Cl9brz "These results suggest that over-the-counter doses of both ibuprofen and acetaminophen suppress the protein synthesis response in skeletal muscle after eccentric resistance exercise."

Aug 28, 2023 · 10 likes · 2 shares · 66 followers View post →
Curtis Ray Bizelli
@PropheticRay · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do Differently https://t.co/ufeKrsftmD

Mar 16, 2025 · 11,511 followers View post →
ASTARTE-31OCT
@Astarte_31OCT · X

https://t.co/J4Q4H2b2Pa

Oct 8, 2025 · 3,174 followers View post →
blubber_bones
@blubber_bones · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do ... https://t.co/Q1e6oJ4XA2 via @YouTube

Mar 15, 2025 · 1,105 followers View post →
blubber_bones
@blubber_bones · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do ... https://t.co/hhHFOYP2sX via @YouTube

Mar 15, 2025 · 1,105 followers View post →
Prashant
@p7p8p9p · X

RT @BasB3: @Jozo_Grgic Also interesting: https://t.co/ZPZ3Cl9brz "These results suggest that over-the-counter doses of both ibuprofen and a…

Aug 29, 2023 · 2 shares · 183 followers View post →

All mentions

Avoiding Common Post-Workout Nutrition Mistakes

This video explores common post-workout nutrition mistakes that athletes make and provides insights on how to optimize recovery. Focus on the importance of combining essential amino acids with protein for enhanced…

Thomas DeLauer · Mar 15, 2025 47,367 views
ASTARTE-31OCT
@Astarte_31OCT · X

https://t.co/J4Q4H2b2Pa

Oct 8, 2025 · 3,174 followers View post →
Curtis Ray Bizelli
@PropheticRay · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do Differently https://t.co/ufeKrsftmD

Mar 16, 2025 · 11,511 followers View post →
blubber_bones
@blubber_bones · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do ... https://t.co/Q1e6oJ4XA2 via @YouTube

Mar 15, 2025 · 1,105 followers View post →
blubber_bones
@blubber_bones · X

The Post-Workout Nutrition Mistakes I Wish I Stopped Sooner - What I do ... https://t.co/hhHFOYP2sX via @YouTube

Mar 15, 2025 · 1,105 followers View post →
Prashant
@p7p8p9p · X

RT @BasB3: @Jozo_Grgic Also interesting: https://t.co/ZPZ3Cl9brz "These results suggest that over-the-counter doses of both ibuprofen and a…

Aug 29, 2023 · 2 shares · 183 followers View post →
Javier Méndez Amago
@Mendezja_fis · X

RT @BasB3: @Jozo_Grgic Also interesting: https://t.co/ZPZ3Cl9brz "These results suggest that over-the-counter doses of both ibuprofen and a…

Aug 28, 2023 · 2 shares · 47 followers View post →
Bas
@BasB3 · X

@Jozo_Grgic Also interesting: https://t.co/ZPZ3Cl9brz "These results suggest that over-the-counter doses of both ibuprofen and acetaminophen suppress the protein synthesis response in skeletal muscle after eccentric resistance exercise."

Aug 28, 2023 · 10 likes · 2 shares · 66 followers View post →