PubHawk
Nature April 2002 PMID 11898023

Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase.

James P Jackson, Anders M Lindroth, Xiaofeng Cao, Steven E Jacobsen

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14
Peak: 2 in Mar 2022
across 6 sources since May 2008

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AI synopsis

What people are saying

The comments are mostly light-hearted and informal, such as referencing funny gene names and humorous remarks about science, which demonstrate a low level of serious interest or engagement with the article's scientific content.

AgreementNeither agree nor disagree

The discussions do not clearly support or oppose the scientific findings, showing neutrality.

InterestNeutral interest

The mentions are brief and lack detailed engagement, indicating low interest.

EngagementNeutral engagement

The comments are casual and do not delve into scientific implications, reflecting minimal engagement.

ImpactNeutral impact

The discussions appear superficial without contributing to or emphasizing the importance of the research findings.

Abstract in brief

  • The study explains how gene silencing involves heterochromatin formation, which is marked by DNA methylation at CpNpG sites and histone H3 Lys 9 methylation, with HP1 protein playing a key role in recognizing these modifications.
  • The researchers identified the KRYPTONITE gene in the plant Arabidopsis thaliana, which encodes a methyltransferase that specifically adds methyl groups to histone H3 Lys 9, and found that its loss results in decreased DNA methylation and reactivation of transposons.
  • The findings suggest that H3 Lys 9 methylation controls CpNpG DNA methylation through interaction with the CMT3 methyltransferase, which binds to methylated histones and maintains gene silencing in plants.]
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american biologist
@95thoughts · X

@ctrlcreep Kryptonite https://t.co/HXIvaxovaV

Jul 27, 2021 · 4 likes · 1,408 followers View post →
Instante Biotec
@InstanteBiotec · X

Às vezes a ciência pode ser muito engraçada.

Mar 20, 2019 · 1 like · 627 followers View post →

All mentions

Steven Andrew Yates
@steven_a_yates · X

Favorite funny gene names in plants https://t.co/fE5VxNJa4T via @YouTube

Mar 12, 2022 · 356 followers View post →
american biologist
@95thoughts · X

@ctrlcreep Kryptonite https://t.co/HXIvaxovaV

Jul 27, 2021 · 4 likes · 1,408 followers View post →
Instante Biotec
@InstanteBiotec · X

Às vezes a ciência pode ser muito engraçada.

Mar 20, 2019 · 1 like · 627 followers View post →
The Role of Methylation in Gene Expression | Learn Science at ...
Blogs

... 10.1038/nature731 (link to article). Jones, P. A., & Taylor, S. M. Cellular differentiation, cytidine analogs, and DNA methylation. Cell 20, 85–93 (1980).

Dec 16, 2025 View →
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 ...
Blogs

Published online 17 March 2002, DOI 10.1038/nature731. 1. Rea, S. et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases ...

Dec 16, 2025 View →
目次 | Nature | Nature Portfolio
News

doi: 10.1038/nature731. 日本語要約 Full Text PDF. 細胞：p63とp73はDNA損傷に応じて起こるp53依存性アポトーシスに必要である. p63 and p73 are required for p53 ...

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doi:10.1038/nature731. Jacob Y, Martienssen RA (2011) Chromatin reprogramming: gender equality during Arabidopsis germline differentiation. Curr Biol 21:R20 ...

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Gene or Superhero?? Let's play with Arabidopsis genes.
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348 likes, 2 comments - research_goes_slowly on November 4, 2025: "Gene or Superhero?? Let's play with Arabidopsis genes.".

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DNA Methylation Readers in Plants
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doi:10.1038/nature731. 47. H. Stroud, M.V.C. Greenberg, S. Feng, Y. V. Bernatavichute, S.E. Jacobsen,. Comprehensive analysis of silencing ...

May 20, 2022 View →
MORC Family ATPases Required for Heterochromatin ...
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doi:10.1038/nature731 Medline. 3. F. Malagnac, L. Bartee, J. Bender, An Arabidopsis. SET domain protein required for maintenance but not.

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Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and ...
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10.1038/nature731. Article PubMed Google Scholar. Soppe WJ, Jasencakova Z, Houben A, Kakutani T, Meister A, Huang MS, Jacobsen SE, Schubert I ...

May 29, 2008 View →