N Engl J Med May 2002 PMID 12023994

Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

David E Cummings, David S Weigle, R Scott Frayo, Patricia A Breen, Marina K Ma, E Patchen Dellinger, Jonathan Q Purnell

Download social card

Mentions

Peak: 7 in Mar 2023

across 5 sources since Oct 2022

Extended reach

305,866

potential audience

Total likes

6,217

Video views

226,661

Mentions per month

Oct 2022 – Mar 2025

Where it's discussed

News10 articles
X / Twitter8 posts
Blogs6 articles
YouTube4 videos
Facebook2 posts

AI synopsis

What people are saying

Overall, discussions express strong agreement with the findings, as seen in supportive phrases like 'ghrelin's role in regulating appetite,' and demonstrate interest through questions about therapeutic implications. The tone combines curiosity with brief technical insights, indicating a moderate level of engagement and perceived impact on medical research.

AgreementModerate agreement

Most discussions acknowledge the study’s findings, particularly around ghrelin's role in weight regulation post-diet and surgery, showing general support for the conclusions.

InterestHigh interest

Participants display high curiosity about the biological mechanisms involving ghrelin and its implications for weight management and treatments.

EngagementModerate engagement

The comments reflect some depth, with references to hormonal functions and potential clinical relevance, though not overly technical.

ImpactModerate impact

The debates hint at potential influence on future research and clinical practices, but mostly remain within academic and health community discussions.

Abstract in brief

Diet-induced weight loss leads to a significant increase (24%) in plasma ghrelin levels, which are normally elevated before meals and decrease after eating, suggesting ghrelin's role in regulating appetite and body weight.
In contrast, after gastric bypass surgery, despite substantial weight loss (36%), patients have much lower ghrelin levels (around 77% lower than normal-weight controls), and typical daily fluctuations of ghrelin are absent, indicating impaired hormone secretion.
These findings imply that while ghrelin may help in long-term weight regulation after dieting, gastric bypass surgery suppresses ghrelin levels, which could contribute to the procedure’s effectiveness in reducing appetite and maintaining weight loss.

Read the full abstract

@DueDoctor · X

@cremieuxrecueil It's ghrelin https://t.co/Wff5AIos7p

Mar 12, 2025 · 2 likes · 9,470 followers View post →

Clincal Dietitian

@ixi_96 · X

Mar 7, 2023 · 6 shares · 200 followers View post →

ʟᴇᴠᴇ ᴘᴀʟᴇꜱᴛɪɴᴀ

@Leve48Palestina · X

Mar 6, 2023 · 6 shares · 226 followers View post →

مصباح

@DrMesbah_ · X

Mar 6, 2023 · 6 shares · 1,837 followers View post →

@Am_Lou64 · X

Mar 5, 2023 · 6 shares · 47 followers View post →

Ayat samman

@samman2012 · X

Mar 5, 2023 · 6 shares · 837 followers View post →

Think twice

@IBN7777 · X

Mar 5, 2023 · 6 shares · 77 followers View post →

د. عمار تنكل

@DrAmmarTonkal · X

Mar 5, 2023 · 18 likes · 6 shares · 66,428 followers View post →

Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Why You're Gaining Weight Back After Dieting (Explaining the Science of How to Keep It OFF!)

Debunking the Top 3 Weight Loss Myths in a Scientific Context

Understanding Physiological Factors Behind Weight Regain after Loss

Understanding Body Weight Regulation and Challenges After Weight Loss