July 2002 PMID 12100180

The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.

T Hakozaki, L Minwalla, J Zhuang, M Chhoa, A Matsubara, K Miyamoto, A Greatens, G G Hillebrand, D L Bissett, R E Boissy

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Mentions

Peak: 3 in Jun 2019

across 5 sources since Jun 2019

Extended reach

548,274

potential audience

Total likes

11,023

Video views

497,654

Mentions per month

Jun 2019 – Nov 2025

Where it's discussed

News27 articles
X / Twitter17 posts
YouTube6 videos
Facebook3 posts
Blogs2 articles

AI synopsis

What people are saying

The overall tone reflects high agreement and interest, as seen in comments affirming niacinamide's effectiveness and sharing scientific references, with phrases like 'proven time and again' and 'highly recommend,' which demonstrate enthusiasm and trust in the research. The engagement is moderate, with some users citing scientific sources and linking to expert content, while the impact is high, emphasizing its relevance for skincare routines and community acceptance.

AgreementStrong agreement

Most discussions strongly support the findings, emphasizing niacinamide's role in skin lightening and its effectiveness based on scientific studies.

InterestHigh interest

Participants demonstrate high interest, sharing related resources, praising the research, and discussing practical skincare implications.

EngagementModerate engagement

While many express support and share additional insights, the tone remains primarily supportive rather than deeply analytical, hence moderate engagement.

ImpactHigh impact

The discussions highlight the strong social impact, with mentions of its popularity in the skincare community and potential benefits for hyperpigmentation concerns.

Abstract in brief

This study explores how niacinamide, a compound found in skincare products, can help reduce skin pigmentation, especially hyperpigmentation common in several skin conditions and desires for lighter skin among Asian women.
Laboratory tests showed niacinamide doesn't stop melanin production directly but significantly inhibits the transfer of melanosomes (pigment-carrying structures) from melanocytes to skin cells, which leads to less skin darkening.
In clinical trials with Japanese women, applying niacinamide moisturizer led to noticeable lightening of the skin and reduced hyperpigmentation within just 4 weeks, confirming its potential as an effective skin lightening agent by blocking melanosome transfer.]

Read the full abstract

All mentions

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Niacinamide in Skincare: Effects, Myths, and Scientific Insights

Niacinamide is a popular ingredient in many skincare products. This video explores its effectiveness in reducing skin pigmentation by inhibiting melanosome transfer, backed by scientific research and clinical trials…

Incipedia Skincare · Oct 18, 2023 63,257 views

Niacinamide's Role in Reducing Hyperpigmentation and Melanosome Transfer

This video explores how niacinamide helps reduce skin pigmentation by inhibiting melanosome transfer, leading to skin lightening. Clinical trials show significant hyperpigmentation reduction within four weeks of use.

GURUCHECK · Sep 21, 2024 13,595 views

"Niacinamid ist erst ab 10 % wirksam!" #incipedia #hautpflege #skincare

Incipedia Skincare · Oct 24, 2023 12,771 views

Effective Skincare with Niacinamide and Vitamin E for Acne and Hyperpigmentation

Discover the scientifically proven benefits of Vitamin E and Niacinamide in skincare routines. This guide explores how these ingredients can help reduce acne and hyperpigmentation, offering insights into their…

Belezuras · Jan 18, 2024 68 views

Niacinamide's Role in Reducing Skin Pigmentation and Hyperpigmentation

This video explores how niacinamide helps reduce skin pigmentation by inhibiting melanosome transfer from melanocytes to skin cells, leading to skin lightening and reduced hyperpigmentation, as demonstrated in clinical…

Dr. Sean Skin School · Jun 23, 2023 59 views

Four Critical Mistakes Destroying Your Skin Barrier in Black Skin

This video explains four common errors that damage the skin barrier in Black skin. It emphasizes proper hydration, gentle exfoliation, avoiding harsh products, and daily SPF to maintain healthy skin and protect against…

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Nuala Woulfe

@Nuala_Woulfe · X

Study suggest Niacinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes. #melanin #niacinamide #skin https://t.co/hxaPODWjaA

May 24, 2025 · 1,786 followers View post →

Nectapharma

@nectapharma · X

Feb 8, 2025 · 636 followers View post →

alexandra

@theyoungestutke · X

Nov 30, 2024 · 2 likes · 350 followers View post →

saykomelik ecocare ✨

@saykomelik · X

anlatacagim seylerin gorselini buradan aldim cunku cok guzel anlatilmis @LabMuffin ✨ https://t.co/bUxdd6FGCB

May 27, 2024 · 374 followers View post →

ซันเล่าเรื่องผิว Sean Skin School

@DrSeanSkinSch · X

#แชร์ได้ชัวร์ อ้างอิงแล้ว

Sep 5, 2023 · 1 like · 13,280 followers View post →

fufu |

@rundinganfoe · X

Sumber: https://t.co/bbsyBCAGVq https://t.co/bgwmKqAeD6 https://t.co/COF2wGc23j https://t.co/adgJCPrSTl https://t.co/wAAhn59zBf https://t.co/zl45vhzR2G https://t.co/zN0wlzZSFE https://t.co/Qlv719sUBk

Oct 25, 2021 · 2,877 followers View post →

lemon stealing whore

@becomekarma · X

@edgar_rrrrrr If ur going for skin lightening tho niacinamide might help https://t.co/lpta59p56D

Aug 18, 2021 · 4,964 followers View post →

Scientific Skincare

@scienceandskin · X

References Hakozaki, T., Minwalla, L., Zhuang, J., Chhoa, M., Matsubara, A., Miyamoto, K., ... & Boissy, R. E. (2002). The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. British Journal of Dermatology, 147(1), 20-31

Jul 15, 2021 · 123 followers View post →

Scientific Skincare

@scienceandskin · X

Nicinamide has been proven time and again to help lighten hyperpigmentation (https://t.co/1XQASKL4FQ). It's much beloved in the skincare community for that reason.

Jul 15, 2021 · 123 followers View post →

tess

@brownriicesyrup · X

@reneIogy https://t.co/vbTH2yIRqL

May 3, 2021 · 383 followers View post →

aims⋆.ೃ࿔*:･ೀ

@belalangkebalik · X

@chichiochi_ @aquarianszz @sansnurchy https://t.co/yQbzWIXc7Q

Feb 19, 2021 · 67 followers View post →

Daughters of Malaya®

@domskincare · X

Jom guna Niacinamide sebagai contoh. In this study, 5% Niacinamide moisturizer dapat mengurangkan hyperpigmentation. https://t.co/IhV5NH6xOo

Oct 19, 2020 · 4 likes · 5,390 followers View post →

id.gaff

@id_gafff · X

RT @friedelcraft: 2% nicotinamide + spf 15 dapat mencerahkan kulit setelah penggunaan 4 minggu https://t.co/yrC9lhBqWT https://t.co/JIFM3Z…

Aug 19, 2020 · 1 share · 78 followers View post →

Kiki

@friedelcraft · X

2% nicotinamide + spf 15 dapat mencerahkan kulit setelah penggunaan 4 minggu https://t.co/yrC9lhBqWT https://t.co/JIFM3ZZ1QX

Jun 27, 2020 · 4 likes · 1 share · 7,171 followers View post →

POPLINE

@POPLINE_org · X

RT @EurekaMag: The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer https://t.co/jXtOJSe4Yc…

Jun 27, 2019 · 2 shares · 5,271 followers View post →

Science Alerts

@Science_Alerts · X