August 2002 PMID 12148098

Effect of low-carbohydrate high-protein diets on acid-base balance, stone-forming propensity, and calcium metabolism.

Shalini T Reddy, Chia-Ying Wang, Khashayar Sakhaee, Linda Brinkley, Charles Y C Pak

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Mentions

Peak: 2 in Jul 2022

across 4 sources since Jul 2022

Extended reach

19,552

potential audience

Total likes

219

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12,128

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Jul 2022 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

Discussions highlight detailed biochemical responses, such as the proximal tubule's role in citrate reabsorption to buffer acidity, with phrases like 'tries to augment citrate reabsorption' indicating technical engagement. The tone alternates between scientific curiosity and concern for health effects, reflecting a moderate but engaged consideration of the study's findings.

AgreementNeither agree nor disagree

The posts show mixed opinions, with some acknowledging the dietary effects on acid-base balance while others suggest concerns or dismiss them.

InterestModerate interest

Posts demonstrate moderate curiosity, primarily focused on biochemical processes and health implications.

EngagementModerate engagement

Discussions engage in details about renal physiology and diet impacts, indicating a moderate degree of participation.

ImpactModerate impact

The discussions imply awareness of health risks like kidney stones and bone loss, but no consensus on broad significance.

Abstract in brief

Low-carbohydrate high-protein (LCHP) diets are often used for weight loss and can cause significant changes in the body's acid-base balance, urine composition, and calcium metabolism.
The study found that following an LCHP diet decreases urine pH, increases net acid excretion, reduces urinary citrate (which helps prevent kidney stones), and raises urinary calcium levels; these changes may elevate the risk of kidney stone formation.
Additionally, the diet appears to negatively affect calcium balance and bone health, as suggested by increased markers of bone resorption and decreased serum osteocalcin, indicating a potential risk for bone loss over time.

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Caz

@MarshmalloRambo · X

@ChadGPT_Chadbot @J37746526 https://t.co/Fa3jvB65yj https://t.co/muyjHqsNub https://t.co/sB0MNIeVAI

Sep 9, 2025 · 2 likes · 39 followers View post →

rpwi

@rpwi10 · X

@jacksonhinklle You're going to acidify your body. https://t.co/hfGziesK3Q

Nov 2, 2022 · 32 followers View post →

Syed Shahrul Naz

@drshahrul80 · X

RT @Api_chew: 14/ The proximal tubule tries to augment citrate reabsorption to buffer the acidity leading to a reduction in urine citrate.…

Jul 8, 2022 · 1 share · 6,929 followers View post →

Api Chewcharat

@Api_chew · X

Jul 7, 2022 · 14 likes · 1 share · 421 followers View post →