PubHawk
N Engl J Med December 2002 PMID 12466506

A comparison of rate control and rhythm control in patients with atrial fibrillation.

D G Wyse, A L Waldo, J P DiMarco, M J Domanski, Y Rosenberg, E B Schron, J C Kellen, H L Greene, M C Mickel, J E Dalquist, S D Corley

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Mentions

65
Peak: 8 in Jul 2020
across 4 sources since Nov 2018

Extended reach

377,126
potential audience

Total likes

2,790

Video views

203,082

Mentions per month

Nov 2018 – Jul 2025

Where it's discussed

  • X / Twitter34 posts
  • News14 articles
  • Blogs12 articles
  • YouTube5 videos

AI synopsis

What people are saying

The discussions reveal a consensus that the AFFIRM trial established no significant survival benefit between rate and rhythm control, with examples like references to the trial’s findings and mentions of adverse events. The tone is informative and analytical, emphasizing clinical significance and historical context, which supports the overall high engagement and interest levels.

AgreementModerate agreement

Most discussions acknowledge the findings of the study, especially referencing the AFFIRM trial and its conclusion that both strategies are comparable, with some posts emphasizing no survival benefit of rhythm control.

InterestHigh interest

Many posts show active engagement with the topic, discussing historical context, trial results, and clinical implications, indicating high interest.

EngagementHigh engagement

Users are deep in the discussion, citing specific trials, methodologies, and clinical implications, demonstrating a strong level of engagement.

ImpactModerate impact

The discussions could influence clinical perspectives on AF management strategies, but primarily within medical communities; thus, the perceived impact is moderate.

Abstract in brief

  • The study compared two treatment strategies for atrial fibrillation: rhythm control, which aims to restore normal heart rhythm, and rate control, which allows AF to persist but manages heart rate, with anticoagulants used in both.
  • Results showed no significant survival benefit of rhythm control over rate control over five years, with mortality rates of 23.8% and 21.3%, respectively.
  • Patients on rhythm control experienced more hospitalizations and adverse drug effects, and anticoagulation remains crucial in both groups to prevent strokes, especially when warfarin levels are not well-controlled.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Journal Club
@journalclubju · X

#Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CONTROL AND RHYTHM CONTROL IN PATIENTS WITH ATRIAL FIBRILLATION الطب الباطني- تخصص أمراض القلب https://t.co/njuNuASWh7

Jul 14, 2020 · 13 likes · 8 shares · 713 followers View post →
CardioSmart
@CardioSmart · X

(6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antiarrhythmic

Sep 12, 2020 · 9 likes · 5 shares · 23,462 followers View post →
猫になりたい薬剤師
@Vannyamoto · X

A comparison of rate control and rhythm control in patients with atrial fibrillation. - PubMed - NCBI AFFIRM試験 心房細動に対するレート vs. リズム 死亡率に差はないが，副作用の観点からレートコントロールの方が良いのではないか，という研究結果 https://t.co/FfbFjuhf4u

Apr 13, 2019 · 7 likes · 1 share · 1,043 followers View post →
Adrian Soto-Mota
@AdrianSotoMota · X

El estudio clásico es el AFFIRM: ¿Control de ritmo o control de foco en pacientes con fibrilación auricular? https://t.co/nsGk36T70X

Jan 31, 2022 · 5 likes · 9,162 followers View post →
Tororo_ph@EP Univ. oshademic
@tororo__ph · X

Sep 29, 2022 · 5 likes · 1 share · 6,800 followers View post →
Mounir Basalus (Ⲃⲁⲥⲓⲗⲓⲟⲥ)
@Basalus · X

2/ AF management has two main strategies: •Rate control: manage heart rate •Rhythm control: restore & maintain sinus rhythm Historically, both were considered equivalent (AFFIRM trial, 2002). But the landscape has changed. [https://t.co/ky8HlooyoA]

Apr 6, 2025 · 4 likes · 4,954 followers View post →

All mentions

Mohammad Aleidi
@aleidimed · X

RT @Basalus: 2/ AF management has two main strategies: •Rate control: manage heart rate •Rhythm control: restore & maintain sinus rhythm H…

Apr 7, 2025 · 291 followers View post →
Mounir Basalus (Ⲃⲁⲥⲓⲗⲓⲟⲥ)
@Basalus · X

2/ AF management has two main strategies: •Rate control: manage heart rate •Rhythm control: restore & maintain sinus rhythm Historically, both were considered equivalent (AFFIRM trial, 2002). But the landscape has changed. [https://t.co/ky8HlooyoA]

Apr 6, 2025 · 4 likes · 4,954 followers View post →
色々自粛中(ガラス細工の様な繊細なハートを持つ貴公子
@ECGEPSCADEVICE · X

RT @matsu58328: A comparison of rate control and rhythm control in patients with atrial fibrillation https://t.co/R6cwVAPE11

May 18, 2024 · 1 share · 9,374 followers View post →
matsuneko
@matsu58328 · X

A comparison of rate control and rhythm control in patients with atrial fibrillation https://t.co/R6cwVAPE11

May 18, 2024 · 2 likes · 1 share · 1,148 followers View post →
色々自粛中(ガラス細工の様な繊細なハートを持つ貴公子
@ECGEPSCADEVICE · X

RT @tororo__ph:

Sep 29, 2022 · 1 share · 9,374 followers View post →
Tororo_ph@EP Univ. oshademic
@tororo__ph · X

Sep 29, 2022 · 5 likes · 1 share · 6,800 followers View post →
Branden Engorn
@BrandenEngorn · X

RT @EMARIANOMD: Excellent discussion by @MSharifpourMD about managing perioperative atrial fibrillation #CSAAnnual22 Cites AFFIRM trial h…

Apr 8, 2022 · 5 shares · 2,102 followers View post →
Rita “Proudly Vaccinated” Agarwal MD
@Ritaagarwal6 · X

RT @EMARIANOMD: Excellent discussion by @MSharifpourMD about managing perioperative atrial fibrillation #CSAAnnual22 Cites AFFIRM trial h…

Apr 8, 2022 · 5 shares · 2,472 followers View post →
John W. Patton III, MD, MBA
@drjohnpatton · X

RT @EMARIANOMD: Excellent discussion by @MSharifpourMD about managing perioperative atrial fibrillation #CSAAnnual22 Cites AFFIRM trial h…

Apr 8, 2022 · 5 shares · 1,588 followers View post →
Juan G. Ripoll, MD
@JuanGRipoll1 · X

RT @EMARIANOMD: Excellent discussion by @MSharifpourMD about managing perioperative atrial fibrillation #CSAAnnual22 Cites AFFIRM trial h…

Apr 8, 2022 · 5 shares · 2,133 followers View post →
Milad Sharifpour, MD
@MSharifpourMD · X

RT @EMARIANOMD: Excellent discussion by @MSharifpourMD about managing perioperative atrial fibrillation #CSAAnnual22 Cites AFFIRM trial h…

Apr 8, 2022 · 5 shares · 21,726 followers View post →
Adrian Soto-Mota
@AdrianSotoMota · X

El estudio clásico es el AFFIRM: ¿Control de ritmo o control de foco en pacientes con fibrilación auricular? https://t.co/nsGk36T70X

Jan 31, 2022 · 5 likes · 9,162 followers View post →
koureiigaku
@koureiigaku · X

また過去の報告*では慢性化した心房細動患者を対象に洞調律化療法を評価していますが、本試験では早期心房細動患者を対象に診断直後の洞調律化療法を評価しまた参加者の54%が登録時に洞調律でした。 https://t.co/KX0B5xfuqh https://t.co/4I1cYUHW2N https://t.co/5mWmM6wNca https://t.co/Iwirfb16GQ

Jan 10, 2021 · 850 followers View post →
koureiigaku
@koureiigaku · X

過去に洞調律化療法は心拍数管理よりも良い転帰を示さなかったと報告*されています。 https://t.co/KX0B5xfuqh https://t.co/4I1cYUHW2N https://t.co/5mWmM6wNca https://t.co/Iwirfb16GQ

Jan 8, 2021 · 850 followers View post →
koureiigaku
@koureiigaku · X

本試験において早期洞調律化療法は入院日数に影響しておらず、過去の2つの大規模試験*で洞調律化療法による入院日数増加が報告されていることを考慮すると、本試験の結果には期待が持てます。 https://t.co/4I1cYUHW2N https://t.co/Wm5q6bzrxw

Jan 7, 2021 · 850 followers View post →
koureiigaku
@koureiigaku · X

抗凝固療法による最大限の心房細動関連脳塞栓症予防*や心拍数管理による症状緩和を行っても*も前述の合併症は発生してしまいます。 https://t.co/MzgVjJiBDG https://t.co/4I1cYUHW2N

Dec 22, 2020 · 850 followers View post →
Dr. Márcio Figueiredo EP
@figueiredo_ep · X

RT @CardioSmart: (6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antia…

Sep 12, 2020 · 5 shares · 1,161 followers View post →
CVC
@CVC_Adelaide · X

RT @CardioSmart: (6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antia…

Sep 12, 2020 · 5 shares · 712 followers View post →
Prash Sanders
@PrashSanders · X

RT @CardioSmart: (6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antia…

Sep 12, 2020 · 5 shares · 9,189 followers View post →
Rakesh Gopinath
@drrakeshg1 · X

RT @CardioSmart: (6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antia…

Sep 12, 2020 · 5 shares · 4,806 followers View post →
DJ Lakkireddy
@DJ_Lakkireddy · X

RT @CardioSmart: (6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antia…

Sep 12, 2020 · 5 shares · 6,451 followers View post →
CardioSmart
@CardioSmart · X

(6/11) #AFibAwareness #Tweetorial: The AFFIRM study compared rhythm & rate control. Rhythm control= cardioversion & antiarrhythmic

Sep 12, 2020 · 9 likes · 5 shares · 23,462 followers View post →
Abdulaziz ALHAZMI عبدالعزيز الحازمي
@drhazmi_6 · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 15, 2020 · 8 shares · 5,810 followers View post →
Ahmad Alharbi أحمد بن علي
@ahmadalharbi12 · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 681 followers View post →
نادي الطب
@JU_MedClub · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 4,943 followers View post →
Medicine Club
@JUMedClub · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 2,240 followers View post →
عبدالله
@AOT_21 · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 70 followers View post →
إيهاب الأمير
@Ehab_Alameer · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 2,254 followers View post →
Mohammed Alharbi
@DR_MO44 · X

RT @journalclubju: #Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CON…

Jul 14, 2020 · 8 shares · 1,154 followers View post →
Journal Club
@journalclubju · X

#Journal_Club_JU اللقاء السادس والأخير للدورة الأولى من دورات الجورنال كلوب عنوان المقالة : A COMPARISON OF RATE CONTROL AND RHYTHM CONTROL IN PATIENTS WITH ATRIAL FIBRILLATION الطب الباطني- تخصص أمراض القلب https://t.co/njuNuASWh7

Jul 14, 2020 · 13 likes · 8 shares · 713 followers View post →
د.شعلان العامري
@ShalanAlaamri · X

@drmoutaz ( AFFIRM trial ): In patients with nonvalvular AF, there is no survival benefit between rate and rhythm control, rate-control resulted in a lower incidence of adverse events https://t.co/ehA06NDtzt

May 27, 2020 · 3 likes · 10,149 followers View post →
.┓┏.
@whisperofgecko · X

RT @Vannyamoto: A comparison of rate control and rhythm control in patients with atrial fibrillation. - PubMed - NCBI AFFIRM試験 心房細動に対するレー…

Apr 13, 2019 · 1 share · 198 followers View post →
猫になりたい薬剤師
@Vannyamoto · X

A comparison of rate control and rhythm control in patients with atrial fibrillation. - PubMed - NCBI AFFIRM試験 心房細動に対するレート vs. リズム 死亡率に差はないが，副作用の観点からレートコントロールの方が良いのではないか，という研究結果 https://t.co/FfbFjuhf4u

Apr 13, 2019 · 7 likes · 1 share · 1,043 followers View post →
Leland Stillman, MD
@StillmanMD · X

This #Aprilfoolsday remember that sometimes #doctors make big mistakes that they only figure out once the mortality trends are clear i.e. lots of people have died. The only cure for a bad environment is to change it. #naturecures Drugs = band aids https://t.co/CYoQHWgIYO

Apr 1, 2019 · 3 likes · 24,235 followers View post →