@jaybeebrtweets @AlpacaAurelius Article: The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus PJ RANDLE. P B GARLAND. C N HALES. E A NEWSHOLME Youtube videos: Randle Cycle: If you don't know, now you know The Randle Cycle Part 2: If you didn't know,
The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.
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Oct 2020 – Feb 2025Where it's discussed
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X / Twitter11 posts
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YouTube2 videos
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Participants show strong interest through sharing educational videos and discussing the cycle's role in insulin resistance, often using technical language or referencing the original paper. The tone indicates both respect and curiosity, with some debates about the cycle's implications for dietary choices and diabetes management, reflecting a nuanced engagement with the research's relevance.
Most discussions recognize the importance of the Randle cycle in understanding diabetes and metabolic disturbances, showing general support for the publication's findings.
The discussions demonstrate high interest, with many participants sharing videos, requesting comments, and emphasizing the cycle's significance.
Users are actively engaging, referencing the original study, explaining mechanisms, and debating implications, indicating deep involvement.
While some recognize the article's foundational role, the overall perception suggests moderate impact, as some discussions are more about understanding than immediate application.
Abstract in brief
- The glucose-fatty acid cycle describes how the metabolism of glucose and fatty acids are interconnected, affecting insulin resistance and overall energy use in the body.
- In diabetes mellitus, an imbalance in this cycle contributes to metabolic disturbances by promoting fat accumulation and impairing insulin's ability to regulate blood sugar.
- Understanding this cycle helps explain how excess fatty acids can worsen insulin sensitivity, leading to the complications associated with diabetes.]
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Most liked on X and Blueskyrefs: https://t.co/INdwVltn4O https://t.co/yygU4eZHgq
@bfhhealth have you seen this https://t.co/u7BfKAWAfs any thoughts?
@robertlufkinmd You'll then need to discuss this with my friend the Professor: I'll put you on to him... Here's the link to the paper Randle PJ, et al. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1 : 785–789, 1963.
@brian_sanders1 https://t.co/pUSIRhxR0A
@CarnivoreAugust You replied to multiple people, not just me. This is a famous paper showing how elevated beta oxidation is synonymous with the diabetic state https://t.co/OrxGU1TLqv. Elevated FFAs cause slower metabolism and vice versa.
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Understanding the Randle Cycle and Its Role in Metabolism and Diabetes
The Randle cycle explanation and myth debunking. Dr. Cywes details the physiology of the cycle and its impact on insulin sensitivity, emphasizing that dietary fat does not cause diabetes and clarifying misconceptions…
Impact of the Glucose-Fatty Acid Cycle on Insulin Resistance in Diabetes
This video explains how the glucose-fatty acid cycle influences insulin sensitivity and metabolic disturbances in diabetes, emphasizing the imbalance that promotes fat accumulation and impairs blood sugar regulation.
@jaybeebrtweets @AlpacaAurelius Article: The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus PJ RANDLE. P B GARLAND. C N HALES. E A NEWSHOLME Youtube videos: Randle Cycle: If you don't know, now you know The Randle Cycle Part 2: If you didn't know,
@brian_sanders1 https://t.co/pUSIRhxR0A
@unclebobmartin @chris_neff_pgh A more detailed and accurate description (technical) https://t.co/CFUBdM96cr
@TarbuckSam @DavidVio2 @ScepticalDoctor I shall work in more depth through the Randle cycle. He did some crucial pioneering work apparently. Have a look at this video where the Randle cycle is explained with the knowledge that we have today. I would like to know your comments on this guy. https://t.co/hDklDWfxsl
@CarnivoreAugust You replied to multiple people, not just me. This is a famous paper showing how elevated beta oxidation is synonymous with the diabetic state https://t.co/OrxGU1TLqv. Elevated FFAs cause slower metabolism and vice versa.
@Themannnagain Errado. Jejum obriga o corpo a fazer lipolise. Lipólise aumenta os acidos graxos livres (AGL) que causam resistência insulínica, possivelmente pelo ciclo de Randle. https://t.co/vtHsX6ulIY
@CharlesStassi It's called the Randle Cycle: https://t.co/dG5IhloMCl
@robertlufkinmd You'll then need to discuss this with my friend the Professor: I'll put you on to him... Here's the link to the paper Randle PJ, et al. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1 : 785–789, 1963.
@bfhhealth have you seen this https://t.co/u7BfKAWAfs any thoughts?
@SeedOilDsrspctr @theberserk64 @jonasirw @2POINT1QUAD And while you focus on non-issues, you’re inflaming yourself with carbs by chronically activating the Randle cycle. Randle et al. 1963. “The Glucose Fatty-Acid Cycle: Its Role in Insulin Sensitivity and the Metabolic Disturbances of Diabetes Mellitus.” https://t.co/SOldwUHyNR
refs: https://t.co/INdwVltn4O https://t.co/yygU4eZHgq
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