Anaesthesia May 2004 PMID 15096238

Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies.

William Notcutt, Mario Price, Roy Miller, Samantha Newport, Cheryl Phillips, Susan Simmons, Cathy Sansom

Download social card

Mentions

8
Peak: 2 in Sep 2017
across 4 sources since Sep 2017

Extended reach

347,116
potential audience

Total likes

11,177

Video views

345,912

Mentions per month

Sep 2017 – May 2022

Where it's discussed

  • YouTube3 videos
  • Facebook2 posts
  • News2 articles
  • X / Twitter1 posts

AI synopsis

What people are saying

Discussions around the article focus on its unique 'n-of-1' trial design and the promising results for THC-based extracts, with users mentioning terms like 'placebo' and 'methodology' to analyze the study's rigor, while tone and context highlight a balanced mix of curiosity and cautious optimism about its implications.

AgreementModerate agreement

Most discussions acknowledge the article's methodology and findings, with some emphasizing its promise for pain management.

InterestModerate interest

Participants show moderate curiosity, discussing methodological details like the placebo-controlled design and the implications of THC's effectiveness.

EngagementModerate engagement

Comments include clarifications and interpretations of the study's design, indicating active engagement with the content.

ImpactNeutral impact

The overall tone suggests the study is interesting but not portrayed as a groundbreaking change yet, reflecting cautious optimism.

Abstract in brief

  • The study involved 34 individual cases examining three cannabis-based medicinal extracts (CBMEs)—containing THC, CBD, or both—used sublingually over 12 weeks to treat chronic neuropathic pain, with initial open-label phases followed by randomized placebo-controlled trials.
  • Results showed that extracts with THC were most effective in reducing symptoms, but dosing varied widely, and side effects were common but similar to those from other psychoactive medications, indicating a learning curve for patients and researchers.
  • These early findings suggest that while CBMEs are promising for pain relief, more detailed and larger-scale studies are needed to better understand their efficacy, safety, and optimal use.]

Top posts

Most liked on X and Bluesky
Nathaniel Marshall
@Nat_Sleep · X

@ShechterAri @rhyscohen @HoyosCamilla The Northcutt paper has been labelled in the table as a case series but it's actually an 34 patient n-of-1 trial design (hence the placebo mention): https://t.co/ePRGkbirCn

Sep 10, 2020 · 1,204 followers View post →

All mentions

Nathaniel Marshall
@Nat_Sleep · X

@ShechterAri @rhyscohen @HoyosCamilla The Northcutt paper has been labelled in the table as a case series but it's actually an 34 patient n-of-1 trial design (hence the placebo mention): https://t.co/ePRGkbirCn

Sep 10, 2020 · 1,204 followers View post →