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Throughout the discussion, posters cite foundational studies like the ALVEOLI and LoV trials, emphasizing their significance, and reference the NEJM publication to contextualize the ongoing debate on optimal PEEP levels, with words like 'important,' 'support,' and 'well-tested' conveying both respect and curiosity about the trial's implications.
Most posts acknowledge the importance of the trial and its relevance to understanding PEEP strategies in ARDS, showing general support.
Discussions highlight a high level of curiosity about the trial's findings, referencing multiple important studies and guidelines.
Some posts delve into detailed analysis of trial data and prior research, indicating thoughtful engagement.
The discussion suggests the article influences clinical considerations and future research directions in ventilatory management.
2004 alveoli trial DOI: 10.1056/NEJMoa032193 549 Pts. TV ~ 6 ml/kg Pplat (24-27) Low PEEP 8.3±3.2 cmh2o (death 24.9%) High PEEP 13.2±3.5 cmh2o (death 27.5%) Result= no significant difference between high or low PEEP https://t.co/tTkuvPT9DC
U are a strong believer of guideline-directed medical therapies (GDMT). U know that following the PEEP table - as used in the ARDSnet study (NEJM 2004; 351(4): 327-36. doi: 10.1056/NEJMoa032193) - is a well-tested way to set PEEP. For FiO2 of 80%, the recommended PEEP is:
The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.co/fYtAgkMnqy Express - Jama 2008 https://t.co/5Xl7e7pdeG ART - Jama 2017 https://t.co/mwf5cCFMWh Essential reading material! #critcare #LIVES2023 #FOAMcc
ARDSネットワークのARMA studyで用いられた対応表はARDSのPEEP値の参考となる．中等症以上のARDSでは，高めのPEEPを用いることも推奨された．メタ解析により高いPEEP設定は，ARDS患者や重症スコアの高い患者の死亡率を減少させる可能性があると報告されたためである． https://t.co/gQaUCQMF3S
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @MegriMohammed: 2004 alveoli trial DOI: 10.1056/NEJMoa032193 549 Pts. TV ~ 6 ml/kg Pplat (24-27) Low PEEP 8.3±3.2 cmh2o (death 24.9%…
Acute respiratory distress syndrome involves lung injury leading to fluid in the air spaces. Ventilatory management employs lung protective strategies, with prone positioning shown to improve oxygenation and reduce…
This episode features expert Ft Andr Nascimento discussing recent advances in ventilatory assistance and management of respiratory failure. He reviews strategies impacting clinical outcomes, different support…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
RT @GasBugZa: The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.…
ALVEOLI published in 2004 in the NEJM was stopped early due to futility. https://t.co/pYVeFRAPFZ #critcare #LIVES2023 #FOAMcc
The most important trials in this space include: ALVEOLI - NEJM 2004 https://t.co/pYVeFRAPFZ LoV Trial - JAMA 2008 https://t.co/fYtAgkMnqy Express - Jama 2008 https://t.co/5Xl7e7pdeG ART - Jama 2017 https://t.co/mwf5cCFMWh Essential reading material! #critcare #LIVES2023 #FOAMcc
RT @MegriMohammed: 2004 alveoli trial DOI: 10.1056/NEJMoa032193 549 Pts. TV ~ 6 ml/kg Pplat (24-27) Low PEEP 8.3±3.2 cmh2o (death 24.9%…
RT @MegriMohammed: 2004 alveoli trial DOI: 10.1056/NEJMoa032193 549 Pts. TV ~ 6 ml/kg Pplat (24-27) Low PEEP 8.3±3.2 cmh2o (death 24.9%…
2004 alveoli trial DOI: 10.1056/NEJMoa032193 549 Pts. TV ~ 6 ml/kg Pplat (24-27) Low PEEP 8.3±3.2 cmh2o (death 24.9%) High PEEP 13.2±3.5 cmh2o (death 27.5%) Result= no significant difference between high or low PEEP https://t.co/tTkuvPT9DC
RT @IM_Crit_: U are a strong believer of guideline-directed medical therapies (GDMT). U know that following the PEEP table - as used in the…
U are a strong believer of guideline-directed medical therapies (GDMT). U know that following the PEEP table - as used in the ARDSnet study (NEJM 2004; 351(4): 327-36. doi: 10.1056/NEJMoa032193) - is a well-tested way to set PEEP. For FiO2 of 80%, the recommended PEEP is:
U are a strong believer of guideline-directed medical therapies (GDMT). U know that following the PEEP table - as used in the ARDSnet study (NEJM 2004; 351(4): 327-36. doi: 10.1056/NEJMoa032193) - is a well-tested way to set PEEP. For FiO2 of 80%, the recommended PEEP is:
"Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome" https://t.co/LT2RRhd4SD #ARDS
@Oothamm https://t.co/oTIZvRQ4a7
Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome | NEJM https://t.co/6iDfdcHoWW
ARDSネットワークのARMA studyで用いられた対応表はARDSのPEEP値の参考となる．中等症以上のARDSでは，高めのPEEPを用いることも推奨された．メタ解析により高いPEEP設定は，ARDS患者や重症スコアの高い患者の死亡率を減少させる可能性があると報告されたためである． https://t.co/gQaUCQMF3S
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