J Strength Cond Res August 2004 PMID 15320650

Acute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonresponders.

Daniel G Syrotuik, Gordon J Bell

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Mentions

12
Peak: 2 in Jul 2024
across 5 sources since Jan 2020

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818,299
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AI synopsis

What people are saying

Comments highlight core ideas from the publication, such as variability in creatine response related to initial muscle profile and endogenous production, exemplified by comments noting different responder tiers and potential cognitive benefits; the tone suggests curiosity and recognition of personalized responses, with phrases like 'likely due to' and 'probably works both ways,' indicating analytical engagement without full consensus.

AgreementModerate agreement

Most comments recognize the article's findings regarding variability in response to creatine, with some posts noting the role of endogenous production.

InterestHigh interest

Discussions demonstrate high curiosity, especially about individual differences and potential cognitive benefits.

EngagementModerate engagement

Posts reflect moderate engagement by referencing specific concepts like responders and nonresponders and discussing their causes.

ImpactModerate impact

The conversations acknowledge the study’s relevance, especially concerning personalized nutrition and potential cognitive effects, though some uncertainty remains.

Abstract in brief

  • This study explored how different individuals respond to a 5-day creatine monohydrate supplement, identifying three response levels: responders, quasi-responders, and nonresponders, based on changes in muscle creatine and phosphocreatine levels.
  • Responders typically had lower initial muscle creatine, more type II muscle fibers (which are linked to strength and power), larger muscle fiber cross-sectional areas, and greater fat-free mass, and they showed significant improvements in leg press strength.
  • Nonresponders often had higher initial muscle creatine levels, fewer type II fibers, smaller muscle fibers, and did not improve in strength after supplementation, suggesting that a person’s initial muscle profile influences how effectively they respond to creatine supplementation.]

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Jeremy Ethier
@JeremyEthier95 · X

If you’re interested in the exact research studies mentioned above - (1) https://t.co/0Q5JTyB0RJ https://t.co/f07xM2ICwO (2) https://t.co/iUhQtJVqes (3) https://t.co/arzAE8L6UA (4) https://t.co/1c1Nuw1JM5 (5) https://t.co/Uj8uGSkbb3

Jul 31, 2023 · 2 likes · 3,306 followers View post →
Coach Wayland | Performance Expert | Craftsman
@WSWayland · X

@TreadAthletics 1/4 people apparently. You maybe be able to get cognitive and nootropic benefits. https://t.co/fHzKElnvZh

Jan 11, 2024 · 1 like · 15,517 followers View post →
yslburner ⚡️
@yslburnerr · X

@_sheyworth https://t.co/F5B9b5SeZn Some people respond better than others - non-responders have no response due to naturally high levels of creatine due to higher endogenous production of it. Probably works both ways.

Jul 19, 2024 · 1 like · 402 followers View post →
yslburner ⚡️
@yslburnerr · X

@vahramovich @giorgallidis Three Tiers of responders likely due to differing endogenous production of creatine in the body https://t.co/F5B9b5SeZn

Jul 19, 2024 · 402 followers View post →

All mentions

DrAlvaroBustamante
@DrAlvaroBustam · X

2) D. G. Syrotuik et al. ´Acute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonresponders`. J Strength Cold Res. 2004, pp. 610-7

Aug 20, 2024 · 30 followers View post →
yslburner ⚡️
@yslburnerr · X

@vahramovich @giorgallidis Three Tiers of responders likely due to differing endogenous production of creatine in the body https://t.co/F5B9b5SeZn

Jul 19, 2024 · 402 followers View post →
yslburner ⚡️
@yslburnerr · X

@_sheyworth https://t.co/F5B9b5SeZn Some people respond better than others - non-responders have no response due to naturally high levels of creatine due to higher endogenous production of it. Probably works both ways.

Jul 19, 2024 · 1 like · 402 followers View post →
Coach Wayland | Performance Expert | Craftsman
@WSWayland · X

@TreadAthletics 1/4 people apparently. You maybe be able to get cognitive and nootropic benefits. https://t.co/fHzKElnvZh

Jan 11, 2024 · 1 like · 15,517 followers View post →
Jeremy Ethier
@JeremyEthier95 · X

If you’re interested in the exact research studies mentioned above - (1) https://t.co/0Q5JTyB0RJ https://t.co/f07xM2ICwO (2) https://t.co/iUhQtJVqes (3) https://t.co/arzAE8L6UA (4) https://t.co/1c1Nuw1JM5 (5) https://t.co/Uj8uGSkbb3

Jul 31, 2023 · 2 likes · 3,306 followers View post →
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