Comments highlight core ideas from the publication, such as variability in creatine response related to initial muscle profile and endogenous production, exemplified by comments noting different responder tiers and potential cognitive benefits; the tone suggests curiosity and recognition of personalized responses, with phrases like 'likely due to' and 'probably works both ways,' indicating analytical engagement without full consensus.
AgreementModerate agreement
Most comments recognize the article's findings regarding variability in response to creatine, with some posts noting the role of endogenous production.
InterestHigh interest
Discussions demonstrate high curiosity, especially about individual differences and potential cognitive benefits.
EngagementModerate engagement
Posts reflect moderate engagement by referencing specific concepts like responders and nonresponders and discussing their causes.
ImpactModerate impact
The conversations acknowledge the study’s relevance, especially concerning personalized nutrition and potential cognitive effects, though some uncertainty remains.
Abstract in brief
This study explored how different individuals respond to a 5-day creatine monohydrate supplement, identifying three response levels: responders, quasi-responders, and nonresponders, based on changes in muscle creatine and phosphocreatine levels.
Responders typically had lower initial muscle creatine, more type II muscle fibers (which are linked to strength and power), larger muscle fiber cross-sectional areas, and greater fat-free mass, and they showed significant improvements in leg press strength.
Nonresponders often had higher initial muscle creatine levels, fewer type II fibers, smaller muscle fibers, and did not improve in strength after supplementation, suggesting that a person’s initial muscle profile influences how effectively they respond to creatine supplementation.]
@TreadAthletics 1/4 people apparently.
You maybe be able to get cognitive and nootropic benefits.
https://t.co/fHzKElnvZh
Jan 11, 2024 · 1 like · 15,517 followersView post →
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yslburner ⚡️
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@_sheyworth https://t.co/F5B9b5SeZn Some people respond better than others - non-responders have no response due to naturally high levels of creatine due to higher endogenous production of it. Probably works both ways.
Creatine is a small peptide that exists naturally in the body. This video explores what happens to your body when you take creatine for 30 days, focusing on its effects on muscle and brain energy production…
Supplements like EAAs, BCAAs, protein powder, or creatine are heavily promoted by the supplement industry. This video examines their actual effectiveness and whether these supplements are worth using, based on…
2) D. G. Syrotuik et al. ´Acute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonresponders`. J Strength Cold Res. 2004, pp. 610-7
@_sheyworth https://t.co/F5B9b5SeZn Some people respond better than others - non-responders have no response due to naturally high levels of creatine due to higher endogenous production of it. Probably works both ways.
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10.1519/12392.1 derly apolipoprotein E e4 carriers. J Neural Transm (Vienna). 45. Brosnan ME, Brosnan JT. The role of dietary creatine. Amino Acids. 2003 ...
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J Strength Cond Res 18:610–617. tation, and bone health in ovariectomized rats. Osteoporos Int doi:10.1519/12392.1 26(4):1395–1404 Syrotuik DG, Bell GJ ...