PubHawk
N Engl J Med September 2004 PMID 15385656

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.

Alan S Go, Glenn M Chertow, Dongjie Fan, Charles E McCulloch, Chi-yuan Hsu

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Mentions

16
Peak: 2 in Apr 2020
across 5 sources since Oct 2018

Extended reach

145,186
potential audience

Total likes

460

Video views

16,445

Mentions per month

Oct 2018 – Nov 2025

Where it's discussed

  • X / Twitter8 posts
  • Instagram4 posts
  • YouTube2 videos
  • News1 articles
  • Blogs1 articles

AI synopsis

What people are saying

Overall, the discussions demonstrate strong agreement and deep engagement, evidenced by users referencing how the research validates the predictive power of eGFR metrics and emphasizing the clinical importance of CKD in cardiovascular health; the tone is confident and highlights the potential for better patient outcomes.

AgreementModerate agreement

Most posts strongly support the article's findings, emphasizing the importance of GFR as a predictor for health outcomes.

InterestHigh interest

Discussions show high curiosity and value, with users highlighting the significance of CKD's link to cardiovascular risks and mortality.

EngagementHigh engagement

Posts include detailed comments on the implications of the research, referencing previous studies and tools like eGFR that improve patient management.

ImpactHigh impact

The social discussions underline the substantial influence of the publication, with some describing it as 'ultimate validation' and a 'game-changer' for nephrology.

Abstract in brief

  • The study found that lower kidney function, measured as glomerular filtration rate (GFR), is associated with a higher risk of death, cardiovascular events, and hospitalization, especially when GFR drops below 60 ml/min per 1.73 m².
  • As GFR decreases further, the risks for these adverse outcomes increase significantly, with the highest risk observed in individuals with GFR less than 15 ml/min per 1.73 m².
  • The findings suggest a direct, graded relationship between declining kidney function and increased health risks, highlighting the importance of monitoring GFR even in less severe stages of kidney dysfunction.
Read the full abstract

Top posts

Most liked on X and Bluesky
ときヲ
@toki_wo_koe · X

「CKD」という疾患概念が定着することになった背景として、腎機能障害がその原因によらずCVDのリスクになると報告したこの研究が大きなインパクト。 #ときメモ Chronic Kidney Disease and the Risks of Death, Cardiovascular Events, and Hospitalization | NEJM https://t.co/GQVGTM1uXy

Apr 30, 2022 · 8 likes · 1 share · 2,590 followers View post →
Namrata Parikh
@NamrataYParikh · X

<2> Background That’s rather unfair!

May 2, 2020 · 4 likes · 1,829 followers View post →
Joel M. Topf, MD FACP
@kidney_boy · X

@thenephrologist @gratefull080504 I really believe that eGFR works. Theses results are really impressive to me: https://t.co/AZq09xeHLb This is the ultimate validation eGFR predicts hospitalization, CV disease and death. I'm not willing to throw a tool like that away #NephJC

Aug 6, 2019 · 3 likes · 63,768 followers View post →
Nicholas Zaorsky, MD MS
@NicholasZaorsky · X

Work from @uretericbud showed importance of competing risk of death. CKD has been recognized as a major driver of other-cause mortality. https://t.co/5kdyoCzcaJ https://t.co/JD3nvtT51f https://t.co/TtkaADwdyy @JCO_ASCO @NEJM @TheLancetOncol https://t.co/7zw5tbcJSV

Dec 3, 2022 · 3 likes · 8,874 followers View post →
Nephrology Journal Club
@NephJC · X

T0 We all know that morbidity and mortality from CAD increases as eGFR declines. Flashback to another @NEJM article https://t.co/5sCNRhO68c #NephJC https://t.co/uS8OetKABf

Apr 29, 2020 · 2 likes · 1 share · 38,560 followers View post →
Graham Abra, MD
@GrahamAbra · X

@AnilMakam @djc795 @mvaduganathan @brendonneuen @RangaswJ @HanCardiomd @ShelleyZieroth @KatherineTuttl8 @AndrewJSauer @drbennisahmed @AKS_KidneyDoc @dranulala Agreed, CKD is a syndrome w/ many causes (DKD, ADPKD ect) The majority of the pts referred to our practice are low risk for ESKD but moderate to high risk for CVD The search for why CKD independently elevates CV risk continues 2 decades on! https://t.co/vswKetqsqr

Jun 28, 2024 · 2 likes · 2,670 followers View post →

All mentions

Graham Abra, MD
@GrahamAbra · X

@AnilMakam @djc795 @mvaduganathan @brendonneuen @RangaswJ @HanCardiomd @ShelleyZieroth @KatherineTuttl8 @AndrewJSauer @drbennisahmed @AKS_KidneyDoc @dranulala Agreed, CKD is a syndrome w/ many causes (DKD, ADPKD ect) The majority of the pts referred to our practice are low risk for ESKD but moderate to high risk for CVD The search for why CKD independently elevates CV risk continues 2 decades on! https://t.co/vswKetqsqr

Jun 28, 2024 · 2 likes · 2,670 followers View post →
Nicholas Zaorsky, MD MS
@NicholasZaorsky · X

Work from @uretericbud showed importance of competing risk of death. CKD has been recognized as a major driver of other-cause mortality. https://t.co/5kdyoCzcaJ https://t.co/JD3nvtT51f https://t.co/TtkaADwdyy @JCO_ASCO @NEJM @TheLancetOncol https://t.co/7zw5tbcJSV

Dec 3, 2022 · 3 likes · 8,874 followers View post →
Satoru Mitsuboshi
@3stars67664378 · X

RT @toki_wo_koe: 「CKD」という疾患概念が定着することになった背景として、腎機能障害がその原因によらずCVDのリスクになると報告したこの研究が大きなインパクト。 #ときメモ Chronic Kidney Disease and the Risks of Dea…

Apr 30, 2022 · 1 share · 1,850 followers View post →
ときヲ
@toki_wo_koe · X

「CKD」という疾患概念が定着することになった背景として、腎機能障害がその原因によらずCVDのリスクになると報告したこの研究が大きなインパクト。 #ときメモ Chronic Kidney Disease and the Risks of Death, Cardiovascular Events, and Hospitalization | NEJM https://t.co/GQVGTM1uXy

Apr 30, 2022 · 8 likes · 1 share · 2,590 followers View post →
Namrata Parikh
@NamrataYParikh · X

<2> Background That’s rather unfair!

May 2, 2020 · 4 likes · 1,829 followers View post →
Dr Priti MD,FASN
@priti899 · X

RT @NephJC: T0 We all know that morbidity and mortality from CAD increases as eGFR declines. Flashback to another @NEJM article https://t.c…

Apr 29, 2020 · 1 share · 8,533 followers View post →
Nephrology Journal Club
@NephJC · X

T0 We all know that morbidity and mortality from CAD increases as eGFR declines. Flashback to another @NEJM article https://t.co/5sCNRhO68c #NephJC https://t.co/uS8OetKABf

Apr 29, 2020 · 2 likes · 1 share · 38,560 followers View post →
Joel M. Topf, MD FACP
@kidney_boy · X

@thenephrologist @gratefull080504 I really believe that eGFR works. Theses results are really impressive to me: https://t.co/AZq09xeHLb This is the ultimate validation eGFR predicts hospitalization, CV disease and death. I'm not willing to throw a tool like that away #NephJC

Aug 6, 2019 · 3 likes · 63,768 followers View post →
Les effets secondaires des insuffisances rénales sur le cœur et les os
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