PubHawk
April 1992 PMID 1548337

Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men.

M L Hartman, J D Veldhuis, M L Johnson, M M Lee, K G Alberti, E Samojlik, M O Thorner

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Mentions

66
Peak: 6 in Jul 2020
across 6 sources since Jun 2020

Extended reach

254,035
potential audience

Total likes

457

Video views

17,154

Mentions per month

Jun 2020 – Jul 2025

Where it's discussed

  • Facebook26 posts
  • X / Twitter21 posts
  • News10 articles
  • YouTube4 videos
  • Blogs3 articles
  • Reddit2 posts

AI synopsis

What people are saying

The overall tone shows strong agreement and interest, exemplified by statements like '48 Hour Fasts = A 5-fold increase in growth hormone secretion' and mentions of broader benefits like fat loss and youthfulness, with detailed references to mechanisms and other studies, indicating a thoughtful and motivated audience engaged with the article's implications.

AgreementModerate agreement

Most discussions support the findings that fasting increases growth hormone secretion, with phrases like '48 Hour Fasts = A 5-fold increase' indicating agreement.

InterestHigh interest

There is a high level of curiosity and enthusiasm, especially about health benefits like fat loss and youthful appearance, shown through questions and positive language.

EngagementHigh engagement

The discussions go beyond summary, referencing other studies, mechanisms like GHRH and somatostatin, and potential benefits, suggesting deep engagement.

ImpactModerate impact

The posts highlight practical impacts such as fat loss, improved sleep, and metabolic health, indicating the findings could influence health practices or beliefs.

Abstract in brief

  • Fasting leads to a significant increase in both the frequency and amplitude of growth hormone (GH) secretory bursts in normal men, resulting in a fivefold rise in GH production over 24 hours.
  • This increase is primarily due to more frequent and larger secretory bursts, with each burst releasing more GH, while the duration of individual secretory events remains unchanged.
  • Despite these changes in GH secretion, levels of insulin-like growth factor I (IGF-I) stay stable after fasting, indicating a complex regulation of GH and IGF-I during starvation.
Read the full abstract

Top posts

Most liked on X and Bluesky
KOJI@プライマルコーチ
@kojija · X

【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 19, 2022 · 27 likes · 4 shares · 2,307 followers View post →
Alex | Forever Alpha Blog
@TheForeverAlpha · X

48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appearance - Improved sleep - Controlled blood sugar Check out the study here: https://t.co/uFJKwNqAKT

Jul 30, 2020 · 24 likes · 6 shares · 35,337 followers View post →
محمد السفياني
@AbuFiras_i · X

رابط الدراسة: https://t.co/xsnoCoS4Oh

Jul 20, 2025 · 1 like · 9,335 followers View post →
Biblical Masculinity
@BibMasculinity · X

@valentinruss089 @fastrlife Boosts androgen receptors/AR sensitivity: 1. https://t.co/qdj2LbmH6C… 2. https://t.co/hGNEYUl9R1 Increases GH: 1. https://t.co/b24mjXwfJc 2. https://t.co/MOGt3PlKDj 3. https://t.co/ndt749dFXd Insulin sensitivity: https://t.co/gJJC8eTWKq…. Fat loss is obvious.

Apr 7, 2023 · 1 like · 7,139 followers View post →
Biblical Masculinity
@BibMasculinity · X

@softner_ @valentinruss089 @fastrlife Boosts androgen receptors/AR sensitivity: 1. https://t.co/7ynTQxA3O6 2. https://t.co/GOo3DP0wtQ Increases GH: 1. https://t.co/po5VGqMBol 2. https://t.co/NJInxxRbsg 3. https://t.co/8kZayU7nxO Insulin sensitivity: https://t.co/AJCiB3lE8n. Fat loss is obvious.

Apr 7, 2023 · 1 like · 7,139 followers View post →
Rand ڕەند
@Randproject_ · X

23- https://t.co/jhFL5muDd0 24- https://t.co/nGFn6sump2 25- https://t.co/wkL3KG1Rl0 26- https://t.co/87oIE1dXCh 27- https://t.co/GmbV0ydXdm 28- https://t.co/RaGkt4ksrr 29- https://t.co/G8QYrnTCOY 30- https://t.co/gqA90EDfQq 31-  https://t.co/QtfR7bu7ru

Mar 14, 2024 · 1 like · 93 followers View post →

All mentions

محمد السفياني
@AbuFiras_i · X

رابط الدراسة: https://t.co/xsnoCoS4Oh

Jul 20, 2025 · 1 like · 9,335 followers View post →
Rand ڕەند
@Randproject_ · X

23- https://t.co/jhFL5muDd0 24- https://t.co/nGFn6sump2 25- https://t.co/wkL3KG1Rl0 26- https://t.co/87oIE1dXCh 27- https://t.co/GmbV0ydXdm 28- https://t.co/RaGkt4ksrr 29- https://t.co/G8QYrnTCOY 30- https://t.co/gqA90EDfQq 31-  https://t.co/QtfR7bu7ru

Mar 14, 2024 · 1 like · 93 followers View post →
vladimir prieto
@vladimirprieto · X

¿te imaginabas que tras 48 hrs de ayuno pasaría esto? https://t.co/OtLzvMt9Hs https://t.co/tKGH54JkXy

Aug 29, 2023 · 1,123 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/9C9r98PSNo En conclusión, los datos actuales sugieren que el aumento de la secreción de GH inducido por la inanición está mediado por una mayor frecuencia de liberación de GHRH y períodos más largos y pronunciados de abstinencia de somatostatina.

Aug 26, 2023 · 8,040 followers View post →
Biblical Masculinity
@BibMasculinity · X

@valentinruss089 @fastrlife Boosts androgen receptors/AR sensitivity: 1. https://t.co/qdj2LbmH6C… 2. https://t.co/hGNEYUl9R1 Increases GH: 1. https://t.co/b24mjXwfJc 2. https://t.co/MOGt3PlKDj 3. https://t.co/ndt749dFXd Insulin sensitivity: https://t.co/gJJC8eTWKq…. Fat loss is obvious.

Apr 7, 2023 · 1 like · 7,139 followers View post →
Biblical Masculinity
@BibMasculinity · X

@softner_ @valentinruss089 @fastrlife Boosts androgen receptors/AR sensitivity: 1. https://t.co/7ynTQxA3O6 2. https://t.co/GOo3DP0wtQ Increases GH: 1. https://t.co/po5VGqMBol 2. https://t.co/NJInxxRbsg 3. https://t.co/8kZayU7nxO Insulin sensitivity: https://t.co/AJCiB3lE8n. Fat loss is obvious.

Apr 7, 2023 · 1 like · 7,139 followers View post →
هشام المصري
@hsmlmry10 · X

https://t.co/ycsM6cw5kk

Mar 6, 2023 · 229 followers View post →
neko2koban090
@neko2koban090 · X

RT @kojija: 【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 23, 2022 · 4 shares · 72 followers View post →
Dahlianna_美容健康コスメ
@DhaliannaB · X

RT @kojija: 【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 20, 2022 · 4 shares · 155 followers View post →
Ale
@forcesteamS · X

RT @kojija: 【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 19, 2022 · 4 shares · 601 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

RT @kojija: 【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 19, 2022 · 4 shares · 125,515 followers View post →
KOJI@プライマルコーチ
@kojija · X

【断食は2日目で成長ホルモンが5倍に】 HGH分泌バーストは断食中により頻繁に発生 GHRH放出の頻度の増加がHGH生産を高める https://t.co/oM9ZAjuN5H

Sep 19, 2022 · 27 likes · 4 shares · 2,307 followers View post →
De-dollarisation 2025-2030
@StarseedSanghi · X

@philipccphilip @Raamadaasan1 Just one: https://t.co/4SCQblVDce

Jul 20, 2022 · 134 followers View post →
Sure Tips Lord
@Sure_Tips_Lord · X

Other studies have found similar effects, with double or triple HGH levels after just 2–3 days of fasting (Source (https://t.co/JdQFnhFzed), Source (https://t.co/ibUsGqS5BH), Source (https://t.co/a9TOU2LBNd)).

Mar 16, 2021 · 166 followers View post →
Alex | Forever Alpha Blog
@TheForeverAlpha · X

RT @TheForeverAlpha: 48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appe…

Jul 31, 2020 · 6 shares · 35,337 followers View post →
maximili0n
@maximili0n · X

RT @TheForeverAlpha: 48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appe…

Jul 30, 2020 · 6 shares · 623 followers View post →
Nikhil S Kesari
@nixnoxiusm · X

RT @TheForeverAlpha: 48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appe…

Jul 30, 2020 · 6 shares · 227 followers View post →
Jason Clements
@jasonclements · X

RT @TheForeverAlpha: 48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appe…

Jul 30, 2020 · 6 shares · 853 followers View post →
English BullTerrier Appreciator
@Brokennfang · X

RT @TheForeverAlpha: 48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appe…

Jul 30, 2020 · 6 shares · 999 followers View post →
Alex | Forever Alpha Blog
@TheForeverAlpha · X

48 Hour Fasts = A 5-fold increase in growth hormone secretion. Which means: - Easier fat loss - A more youthful appearance - Improved sleep - Controlled blood sugar Check out the study here: https://t.co/uFJKwNqAKT

Jul 30, 2020 · 24 likes · 6 shares · 35,337 followers View post →
David
@mitter81 · X

amongst many benefits of intermittent fasting this study shows clinically in men secretion of human growth hormone was enhanced 5x more during a two day fast main benefit is metabolic it keeps your blood sugar & insulin levels low you start burning fat https://t.co/dMiEjB73vA

Jun 7, 2020 · 1,346 followers View post →