Pest Manag Sci April 2005 PMID 15655806

A risk assessment of atrazine use in California: human health and ecological aspects.

Derek W Gammon, Charles N Aldous, Wesley C Carr, James R Sanborn, Keith F Pfeifer

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Mentions

Peak: 3 in Jun 2023

across 2 sources since Nov 2022

Extended reach

119,330

potential audience

Total likes

4,032

Video views

118,722

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Nov 2022 – Apr 2024

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AI synopsis

What people are saying

Discussions feature comments like concern over developmental toxicity in animals and hormoviral disruptions, demonstrating moderate engagement and interest. The tone varies from cautious agreement to curiosity, with references to the risks associated with atrazine and its potential health effects, illustrating a nuanced but moderate overall sentiment towards the publication's significance.

AgreementModerate agreement

Most discussions acknowledge the health and ecological concerns raised by the publication, but some are cautiously accepting of the findings.

InterestModerate interest

Participants show moderate curiosity, often referencing the potential health risks or ecological impacts but without deep dives into technical details.

EngagementModerate engagement

Conversations include some detailed reactions, linking to broader debates about pesticide safety and regulation, indicating moderate effort and thought.

ImpactNeutral impact

While some posts recognize the importance of the study, many suggest limited immediate influence on policy or public behavior, reflecting a cautious perception of impact.

Abstract in brief

The risk assessment of atrazine in California involved analyzing its toxicity through animal studies and estimating human and ecological exposure, leading to the calculation of safety margins.
Acute exposure to atrazine caused developmental toxicity in rabbits and heart toxicity in dogs, while long-term exposure in female rats was linked to malignant mammary tumors, though the genotoxic basis remains uncertain.
The development of these tumors may be due to hormonal disruptions caused by atrazine, such as increased estrogen levels, possibly affecting reproductive hormones and estrogen receptor activity.

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