@ahandvanish @jenbrea @polybioRF This is all so interesting. Even before I was aware of the mast cell involvement in #LongCOVID the blood clotting/endothelial dysfunction associations w oxidative stress had me down some interesting rabbit holes. https://t.co/Gn2TAm3UQF
Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes.
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May 2020 – Jul 2024Where it's discussed
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X / Twitter96 posts
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YouTube2 videos
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What people are saying
The discussions demonstrate a strong interest in the biochemical role of oxidative stress in COVID-19 and cardiovascular disease, with examples like mentions of ACE2 imbalance, super-oxidation, and the potential benefits of antioxidants. The tone is scientific and inquisitive, with references to respected sources like MedCram videos, highlighting an active effort to understand complex biological interactions and their implications for health outcomes.
Many discussions acknowledge the link between oxidative stress and COVID-19 severity, showing general support for the article's premise that oxidative processes are important.
The conversations reveal high interest, with multiple references to detailed mechanisms and potential protective measures, indicating curiosity and engagement.
Participants are actively discussing biochemical pathways, hypothesizing about long-term effects, and sharing resources, reflecting moderate but meaningful engagement.
While most discussions focus on understanding mechanisms and potential interventions, direct calls for action or changes in practice are limited, so the overall impact is moderate.
Abstract in brief
- Oxidative stress, caused by reactive oxygen species (ROS), plays a significant role in the development and progression of atherosclerosis and arterial thrombosis, supported by studies in animals and humans.
- Despite the strong evidence linking oxidative stress to vascular disease, antioxidant treatments have largely failed to reduce cardiovascular death and morbidity in clinical trials, creating a disconnect between cellular research and real-world outcomes.
- The challenges in translating these findings are due to factors such as the lack of specific markers to identify individuals who might benefit from antioxidants, and the complex, localized nature of redox reactions within cells.]
Top posts
Most liked on X and Bluesky@ahandvanish Highly recommend folks watch these two @MedCramVideos if you’re curious about the chemical/physiological process of oxidative stress: https://t.co/rhMyPIe2Ry and https://t.co/YUbDWs9bLw For spoon mgmt - pay atn to cofactors for these processes (glutathione, zinc, copper, iron)
https://t.co/KOWlySY6DQ
I have a hypothesis of what happens in #LongCovid. Through neutrophils (PMNs) and AT-2 increase and AT-1,7 decrease we get severe increase in ROS as already known.... https://t.co/P6YgJJnbjQ https://t.co/oSSYQDsaph
Explains how oxidative stress can potentially be fatal in SARS-cov2. If this is the cause if #MECFS then we could be at very high risk https://t.co/akeXRbN26x
@Harvard2H My pleasure. Medcram has been invaluable to me in understanding ACE2 and it's impact when it's "clogged" up by the Spike and leads to Super-Oxidation and blood vessel (other cellular?)damage. You should put this one in your queue as well.. https://t.co/MJyFD8GNzW
All mentions
Role of Oxidative Stress in COVID-19 Severity and Vascular Damage
COVID19 Update 65 with Dr. Roger Seheult explores how oxidative stress from reactive oxygen species and endovascular inflammation influence COVID-19 severity, providing insights into potential prevention and treatment…
Acetylcysteine's Potential in Treating COVID-19 Complications
This video provides an update on COVID-19 treatment, focusing on the role of Acetylcysteine in countering oxidative stress. Research highlights its potent effects in dissolving arterial thrombi, making it a noteworthy…
RT @MedCramVideos: Coronavirus Pandemic Update 65 with Dr. Seheult: COVID-19 and Oxidative Stress (Prevention & Key Risk Factors) https://…
RT @IVORMECTIN4: @ProfKarolSikora Have you seen this Hypothesis Professor, quite interesting. https://t.co/E2CA6Q8Hh4
@ProfKarolSikora Have you seen this Hypothesis Professor, quite interesting. https://t.co/E2CA6Q8Hh4
RT @911InsideJobAu: Medcram 65 also gets into this process of out-of-control oxidation. https://t.co/Wiykhxv2m7
RT @911InsideJobAu: Medcram 65 also gets into this process of out-of-control oxidation. https://t.co/Wiykhxv2m7
RT @911InsideJobAu: Medcram 65 also gets into this process of out-of-control oxidation. https://t.co/Wiykhxv2m7
Medcram 65 also gets into this process of out-of-control oxidation. https://t.co/Wiykhxv2m7
@zanfr @EricTopol @ValerieJay16 @almallahmo Sorry did not see this. ACE lowers AT II - therefore lowers ROS - but ARB may be more effective. See the YouTube clip on this https://t.co/1wZrCUvqzb https://t.co/csn8QnG2jL
@LongLiveSully @jimmy_dore https://t.co/R8UrPtpb9Q
二年以上前のモノだが…参考に Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/ltQG4WWY9Q via @YouTube
@Mad_Sci_PhD @callanswag2 The whole IL chain of events I got from medcram (YouTube - his series is amazing) describing how COVID cause inflammation/cell death just blew my mind. https://t.co/JFHNCIsEBs
@Med58ll @Turelli_EPFL @PeacockFlu Yes, that's the (not unproven) MedCram thesis from 2020, ⬇️ACE2 ⬆️Oxidative Stress. I think there's a lot more than that though. https://t.co/o8knZSlsf6
RT @DFinsterwalder: I have a hypothesis of what happens in #LongCovid. Through neutrophils (PMNs) and AT-2 increase and AT-1,7 decrease we…
@love_r_republic @activia513 @FinEssentials @MartinKulldorff @caseybmulligan @kerpen @ianmSC Anyone who says there isn't science on youtube is a brainwashed lefty nazi. If Einstein or Tesla were alive they would have youtube videos you mouth breather https://t.co/KVg46PSAaq
@fx_alluka But in a later video, if I’ve understood it correctly, blocking ACE2 can also lead to an imbalance that leads to super oxidation. Starts at :30. https://t.co/urgVYl4LXM
Importance of ACE2 in the virus.. Super oxidation. https://t.co/ZvW4CVhWWB
RT @RogerSeheult: https://t.co/KOWlySY6DQ
@WillBrink You will like this video: https://t.co/KOWlySY6DQ
https://t.co/KOWlySY6DQ
@Canadia29463586 @555SWH My theory it's because of the oxidative stress that Covid puts the body through, and in particularly for those who have some plaque in their arteries already. The fat does a lot of damage when it oxidizes. Strong anti-oxidants, like Glutathione may help. https://t.co/mprASZAESl
@EricTopol @ballmatthew @PNASNews Medcram nailed this over a year ago https://t.co/Pls9gdBKcm
Extend knowledge: COVID-19 and Oxidative Stress https://t.co/1jlVD69Zyt
@markdodds11 @JacquiDeevoy1 @babaloo2roo The spike protein, that the mRNA jabs make our cells create, binds to ACE2 in various organs, disrupting Angiotensin II "balance" creating super-oxidation --> Inflammation, hypoxemia, organ damage. Watch all of this for the molecular biology involved. https://t.co/3xraIbAFpA
RT @Mujhunter: @Harvard2H My pleasure. Medcram has been invaluable to me in understanding ACE2 and it's impact when it's "clogged" up by…
@Harvard2H My pleasure. Medcram has been invaluable to me in understanding ACE2 and it's impact when it's "clogged" up by the Spike and leads to Super-Oxidation and blood vessel (other cellular?)damage. You should put this one in your queue as well.. https://t.co/MJyFD8GNzW
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors) https://t.co/8iLL2DcDTy via @YouTube
RT @RinoRooter: @sonny8s @stkirsch 3/ Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors) https://t.co/bQ08Jwe9D3
@sonny8s @stkirsch 3/ Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors) https://t.co/bQ08Jwe9D3
@ahandvanish Highly recommend folks watch these two @MedCramVideos if you’re curious about the chemical/physiological process of oxidative stress: https://t.co/rhMyPIe2Ry and https://t.co/YUbDWs9bLw For spoon mgmt - pay atn to cofactors for these processes (glutathione, zinc, copper, iron)
RT @briancremy: @richardursomd Yep. Also, Dr. Seheult does a good job showing how oxidative stress conditions (increased in high risk folk…
@richardursomd Yep. Also, Dr. Seheult does a good job showing how oxidative stress conditions (increased in high risk folks) increases that inflammation: https://t.co/SZbdxD2INL And how spike binding to ACE2 on the endothelium of blood vessels leads to thrombosis: https://t.co/MK40HYJdrt
@TKBIKES @trixieC2 I can see why that would work. Been watching this doc since the start of lockdown discuss NO. https://t.co/vxeZZe1JUN
RT @itsanginLA: @ahandvanish @jenbrea @polybioRF This is all so interesting. Even before I was aware of the mast cell involvement in #LongC…
@ahandvanish @jenbrea @polybioRF This is all so interesting. Even before I was aware of the mast cell involvement in #LongCOVID the blood clotting/endothelial dysfunction associations w oxidative stress had me down some interesting rabbit holes. https://t.co/Gn2TAm3UQF
RT @DFinsterwalder: I have a hypothesis of what happens in #LongCovid. Through neutrophils (PMNs) and AT-2 increase and AT-1,7 decrease we…
@SassyCoopster @talkRADIO @mrmarkdolan Educate yourself a little before tweeting about non sense. Start here https://t.co/vvHzhfmc5g You might learn something. You might have an informed opinion then rather just a knee jerk stupid response.
@AlexanderJBrock Re "fit and healthy." https://t.co/VFVSBwVBr1 A man who is obese is not fit and healthy.
@LBC @darrenadam A human body suffers from Oxidative stress on celular level. Fat body, diabetic body, older body more stress already. Covid adds to stress. Fat, diabetic, old bodies are more at risk before chsllenge of Covid19. https://t.co/VFVSBwVBr1
@MAC4U25 And then this. Gives you a good insight in to the basics. Before I throw information at you. https://t.co/akeXRbN26x
I have a hypothesis of what happens in #LongCovid. Through neutrophils (PMNs) and AT-2 increase and AT-1,7 decrease we get severe increase in ROS as already known.... https://t.co/P6YgJJnbjQ https://t.co/oSSYQDsaph
@chrismartenson Chris, do you follow MedCram? You should.. Dr. Seheult, a Med Prof, and Crit Care Pulmo Specilist was discussing this same thing back in early May!! https://t.co/xwv47QHmHS
@DrSubhasree @MedCramVideos https://t.co/VFVSBwVBr1
COVID-19 Actualización 4 ¿Acetilcisteina está en el arsenal terapéutico? https://t.co/mkaTutH4qt https://t.co/ncsiZ971e5
@PHE_uk The problem physiologically is Oxidative stress. https://t.co/VFVSBwVBr1 The body systems are weakened from obesity. So is immunity.
@TherealNihal @DrAseemMalhotra See also. https://t.co/VFVSBwVBr1 Smart guy!
@NaukowyBelkot W sumie to wszystko wiadomo na ten temat https://t.co/RKKy8CglQs Poproszę o podsumowanie od tego odcinka https://t.co/5b73kAfyl7 aż do wiązań siarczkowych https://t.co/bLfJNk0STW
Coronavirus Pandemic Update 65: COVID-19 and j Stress (Preventio... https://@taylorswift13 https://t.co/PArkcqw0UH and via @@bon@team10youtubefnhuu onhk
Here's the science https://t.co/VFVSBwVBr1
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/N5nGvtA2OK lewat @YouTube
@VeronicaChaos https://t.co/nNy8DVl3Kp
@ARanganathan72 Nicely explained in this video https://t.co/huKmFsbLZ8
RT @MedCramVideos: Coronavirus Pandemic Update 65 with Dr. Seheult: COVID-19 and Oxidative Stress (Prevention & Key Risk Factors) https://…
@dccarbene ah that specific aspect better described here. https://t.co/oAD3CvJgAa
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/jv8tsivAN1 via @YouTube
@KarunaGopal1 Should be focusing on foods that increase nitric oxide and decrease oxidative stress on the body. It's not just a disease of the lung but endothelium (blood vessels) as well, causing blood clots and stroke. Foods like chukandar and palak. https://t.co/pYadFcqjZi
Explains how oxidative stress can potentially be fatal in SARS-cov2. If this is the cause if #MECFS then we could be at very high risk https://t.co/akeXRbN26x
@CookedHillary @nikkelly7 @BBCWorld Try again when you have learnt what you are talking about, here is a useful link to the knowledge you lack... https://t.co/6ahUbYJ1pi
@WatMoetJeErMee_ @ui66 @IraWibbelink @OlifaNT Dat zeg ik niet, ze zouden op een (veel) later moment dood gaan. Hier heb je verklarende materie https://t.co/58psYpAjc7 Daarnaast Dr John Campbell, Dr. Eric Berg, PeakProsperity Cov bescherming omvat in de eerste plaats Vit D, daarnaast vit C en zink.
@Pinboard See https://t.co/kRoSAvajtD
https://t.co/ya1qFsshQ5
@DrDemetre YOUR "KAWASAKI DISEASE" CHILDREN: LIKELY EXPERIENCING OXIDATIVE STRESS! Don't be a DS DS (thought you're MD!) We've screen-shot this! IF YOU DON'T START SAVING THESE CHILDREN... !!! https://t.co/rf1VVFUbi4 !!! https://t.co/94QEEhl80Z !!! https://t.co/xxqMjBWsI6
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/LkFlcOYYaY via @YouTube
@farid__jalali @cameronks @srrezaie Apr 29 Dr. Seheult explains the theory that seems most plausible to us here at https://t.co/TTYWh8SAEv : That #COVID19 is primarily a disease of the endothelium. https://t.co/vub84TdNM9
https://t.co/YlvYNwwdWj
#SARSCoV2 induces thrombosis in #CoViD19 patients through angiotensin II dependent ROS production. ACE2 produced angiotensin 1,7 and NO prevent oxidative stress and endothelium damage #coronavirus https://t.co/boSEfLLtaa
@MLChristiansen https://t.co/jiOcXRcnRT Shows a possibility (hypothesis on evidence from medical sources) that Covid19 does more than just screw with your lungs. Also shows why the U.S. might have more difficulty with this. We're a fat country.
@TrevorTrtn @FatEmperor One interesting theory is that COVID-19 is actually a vascular disease and works by magnifying ROS (superoxide) via modifying the angiotensin system. This may account for its predilection for hypertensives and the ROS compromised like diabetics/obese. https://t.co/CpKsW85jP6
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress https://t.co/IoahXS7M3h via @YouTube
RT @howiepask: Watch "Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors)" on YouTube https://t.co/KN…
https://t.co/boSEfLLtaa
https://t.co/onodwSJral
@DoctorKarl @ProfCCollins So a healthy diet high in antioxidants might help protect us from covid-19 (think foods that promote production of nitric oxide) https://t.co/Z2Da4GAkHe
@antihero_kate Actually we thought this virus would hit people with respiratory issues hardest when in fact it's hit people with hypertension, obesity and similar issues more than say people with asthma or COPD https://t.co/QfS1cLX6IH
https://t.co/G9CoM9nDdE
https://t.co/TCleqwfSnX
@Bruceps Please watch episode 64 and 65. Its well known and medication in trial already to address the inflammation and its results on the body. https://t.co/TCleqwfSnX
RT @ArthurVallejomd: The second YouTube video by Professor Seheult from the University of California explaining why #Covid_19 is such a let…
The second YouTube video by Professor Seheult from the University of California explaining why #Covid_19 is such a lethal and morbid disease. Warning: There's a little biochemistry involved. https://t.co/QQXp9OByj3
Dr. Seheult connects the dots beautifully in this video on #SARS_CoV_2 and oxidative stress. @MedCramVideos https://t.co/iMCGOiJsNZ
RT @MedCramVideos: Coronavirus Pandemic Update 65 with Dr. Seheult: COVID-19 and Oxidative Stress (Prevention & Key Risk Factors) https://…
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/OaB8Y5GdWC via @YouTube. WELCOME LITTLE CHILDREN, TO THE GREAT NWO, GMO "DARWINIAN" FLUSH! THOSE WHO TRUST THE MEDIA & SOCIAL MEDA NARATIVE WILL INEVITABLY DIE. RESEARCH THE DATA; OR DIE OFF!
@ProfMakris You might want to watch this. https://t.co/VFVSBwVBr1 Oxidative stress. Endothelium. Covid in via lungs then systemic.
@FatEmperor @SharkyBooi1965 @rinmor Take a look at this....https://t.co/nxeqIPznfm and then read this... https://t.co/kqwlmXibjx
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/MEDGH0fh91 via @YouTube
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/grOjquuNBX via @YouTube
#COVID19 #SARSCoV2 #Coronavirus Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors) @MedCramVideos and Lectures Explained CLEARLY https://t.co/ZlgRWKDbnK
RT @howiepask: Watch "Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Prevention & Risk Factors)" on YouTube https://t.co/KN…
@CotsCardiology @DhirajGuptaBHRS @cardiacpolymath @richardtill @AndyThornley @AshPatwalaMD @mcfinlay @rallamee @ncurzen @SukhNijjer @bmj_latest @FatEmperor More about the hypothesised mechanism for #COVID__19 that donuts may cause. https://t.co/IxEOG70dbp
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/c4ttKChGWh via @YouTube
Coronavirus Pandemic Update 65: COVID-19 and Oxidative Stress (Preventio... https://t.co/okEfvUF35q via @YouTube
https://t.co/E4mxj4Vjb7の65番。 新型コロナウイルス感染症がRAAS系の作用などで活性酸素が増加する様に影響し、それが血管内皮の問題や血栓にも繋がる、という点や肥満・高血圧との関連などを論文を上げて解説。 動画のところに論文へのリンクがあります。 https://t.co/oU6KZAXQJu https://t.co/Cat9zApyLe
@alexwickham I’d have a watch of this. It seems to be connected to oxidative stress. This guy is brilliant! https://t.co/bz2hOkL16d
RT @TimGluckman: #CoronavirusUK. Latest @MedCramVideos looks at #oxidativestress in #CV19. #COPD is not a factor in co-morbidity whereas eg…
RT @MedCramVideos: Coronavirus Pandemic Update 65 with Dr. Seheult: COVID-19 and Oxidative Stress (Prevention & Key Risk Factors) https://…
#CoronavirusUK. Latest @MedCramVideos looks at #oxidativestress in #CV19. #COPD is not a factor in co-morbidity whereas eg obesity / cancer are. How to prevent the oxidative process? Tablets? #Covid19UK https://t.co/Gh3suRoYrc
@kari_jerge You may feel better after watching This https://t.co/sdomeET8lr is more of a q&A. https://t.co/bXOlCJ1Il8 He is an optimist and motivated to keep working on it. Also, has CME avail. C: