Ann N Y Acad Sci December 2004 PMID 15681808

Melatonin relieves the neural oxidative burden that contributes to dementias.

Russel J Reiter, Dun-Xian Tan, Miguel A Pappolla

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Mentions

103
Peak: 26 in Sep 2025
across 3 sources since Sep 2024

Extended reach

1,343,157
potential audience

Total likes

75,357

Video views

1,201,464

Mentions per month

Sep 2024 – Oct 2025

Where it's discussed

  • X / Twitter99 posts
  • Bluesky2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The group demonstrates strong support and curiosity about the neuroprotective effects of melatonin and methylene blue, exemplified by comments praising Chase Hughes' experiences and sharing videos about brain recovery, with words like 'fascinating,' 'amazing,' and 'powerful' indicating excitement, impact, and engagement.

AgreementModerate agreement

Most of the discussions support or are optimistic about the potential benefits of melatonin and related substances, with many referencing personal transformations and testimonials.

InterestHigh interest

Interactions indicate high curiosity and enthusiasm, especially around molecules like methylene blue and melatonin, with many posts sharing stories or recommending further research.

EngagementModerate engagement

Several posts delve into detailed explanations, share videos, and recommend protocols, showing a good level of depth in discussing neuroprotective treatments.

ImpactModerate impact

The discussions reveal that many believe this research could influence brain health treatments or stimulate further scientific exploration, though some caution is evident.

Abstract in brief

  • Melatonin acts as a powerful antioxidant that neutralizes free radicals and reduces oxidative stress in the central nervous system, helping to protect against damage caused by oxygen and nitrogen reactive molecules.
  • The report highlights melatonin’s protective effects in conditions like stroke, Alzheimer's, and Parkinson's disease, where it helps prevent both physical damage to neural tissues and related behavioral impairments.
  • It suggests that using melatonin, possibly alongside other antioxidants, could be a beneficial strategy to combat neural damage linked to aging and neurodegenerative diseases.]

Top posts

Most liked on X and Bluesky
Lucy, nurse for the people not profits.
@LucciaorLucy · X

@7SEES_ You should look up Chase Hughs. He has neurological issues and was given a protocol that changed his life. He has a video on YT about it and I believe his website. https://t.co/SOZbUoIBjC

Jul 17, 2025 · 6 likes · 1 share · 8,953 followers View post →
17WaysFromSunday
@17WaysFrSunday · X

@8traq_truth I have been a fan of Chase Hughes for a few years now specifically regarding his work on the Behavior Panel. Seems to be a pretty down to earth guy, and is a military veteran. https://t.co/gmtqlXpFLk

Apr 22, 2025 · 5 likes · 1 share · 5,399 followers View post →
Dr ₿ ✝️⚡️
@DocMcJ · X

@angelsfly_143 Prayers, so difficult. I just watched this https://t.co/MUCu1P6Btl About a gentleman who used methylene blue to heal his brain from seizures

Jun 21, 2025 · 3 likes · 3,185 followers View post →
Mickey Pittman
@MickeyPittman · X

Learn from this survivor//Update On My Brain Disease https://t.co/MMWSrINrOb via @YouTube

Aug 26, 2025 · 2 likes · 551 followers View post →
holly wiley
@hollyjayewiley · X

Update On My Brain Disease https://t.co/P319Mjfjpr via @YouTube @NCIUniversity how is your condition?? Back when u came out w this video I asked everyone to pray to God to heal u… ..

Oct 19, 2025 · 1 like · 7,526 followers View post →
Jamey Peltonen
@pelt1980 · X

Update On My Brain Disease https://t.co/QIvurSoyDA via @YouTube methylene blue

May 10, 2025 · 1 like · 7,502 followers View post →

All mentions

The Secret Corridor
@SecretCorridor · X

@Nero Imagine if, as a result, you uncover a buried cure that we almost forgot about? Like Chase Hughes: https://t.co/itzRttsWub Or maybe the surgeon Chase found is the man you need. @Nero I do hope you see this if not already familiar. Maybe things really do happen for a reason.

Oct 20, 2025 · 1 share · 875 followers View post →
shortstories
@shortstories.merovingian.club.ap.brid.gy · Bluesky

https://www.youtube.com/watch?v=W4tXqcXeHHM For someone who claims to have lost his memory to such a degree he seems to be using his memory so well in this story making me suspect it is fake although it might not be fake

Oct 19, 2025 View post →
Cynthia Shelnutt
@Blessed2beHere0 · X

Update On My Brain Disease https://t.co/fEwsGZWJ53 via @YouTube

Oct 19, 2025 · 134 followers View post →
holly wiley
@hollyjayewiley · X

Update On My Brain Disease https://t.co/P319Mjfjpr via @YouTube @NCIUniversity how is your condition?? Back when u came out w this video I asked everyone to pray to God to heal u… ..

Oct 19, 2025 · 1 like · 7,526 followers View post →
Debbie Grubbs
@DebbieGrub75719 · X

Update On My Brain Disease https://t.co/4ySr7b65jL via @YouTube @POTUS

Oct 19, 2025 · 125 followers View post →
Steve
@TireSmokinC8 · X

@Nero There are options. Find what works for you. https://t.co/Aj5hkhIJ5x

Oct 18, 2025 · 451 followers View post →
Trace 777
@777_trace · X

@MJTruthUltra https://t.co/4hEz22CPVA

Oct 18, 2025 · 802 followers View post →
Linda Minding
@LindaMinding · X

Update On My Brain Disease https://t.co/MatsWYYOBF via @YouTube Do you know who this is? This video is about his experience with Methelene Blue....

Oct 17, 2025 · 403 followers View post →
M
@Marta29111986 · X

Oct 16, 2025 · 965 followers View post →
Christine Triffet
@Christineisrite · X

https://t.co/Sb2BEHTKGu

Oct 14, 2025 · 454 followers View post →
S.Valentina
@SValentina63 · X

RT @LucciaorLucy: @7SEES_ You should look up Chase Hughs. He has neurological issues and was given a protocol that changed his life. He has…

Oct 12, 2025 · 1 share · 1,425 followers View post →
barry davis
@barrydavis194 · X

https://t.co/Gban65w8NZ

Oct 9, 2025 · 116 followers View post →
Not suddenly dead
@OxideGraphene · X

https://t.co/P6P5YV7EtJ

Oct 9, 2025 · 767 followers View post →
shield maiden
@HRH_Lagertha · X

@jmasseypoet Watch this video by the brilliant Chase Hughes of the Behavior Panel. https://t.co/pEl4nEf4xm

Oct 8, 2025 · 190 followers View post →
Sharp
@allbreadcircus · X

@MarioNawfal Update On My Brain Disease Powerful molecules (high dose melatonin & Methylene Blue) transformed my brain health, stopped my seizures, and might even help someone you know. @jordanbpeterson @MikhailaFuller https://t.co/kYDwdO5PCO

Oct 5, 2025 · 557 followers View post →
Sharp
@allbreadcircus · X

@MikhailaFuller @jordanbpeterson Update On My Brain Disease Powerful molecules (high dose melatonin & Methylene Blue) transformed my brain health, stopped my seizures, and might even help someone you know. @jordanbpeterson @MikhailaFuller https://t.co/kYDwdO5PCO

Oct 5, 2025 · 557 followers View post →
 Chris 
@chris_elid · X

@bryan_johnson Hi Bryan from Southeast Asia, what do you think about this? https://t.co/L9WFgobgCe

Oct 4, 2025 · 49 followers View post →
Peter ⚡
@Tongpo987789 · X

@vazitrades https://t.co/5NNwGfqkYE - related to brain health /not related to your issue

Oct 1, 2025 · 1 like · 144 followers View post →
Alisyn Gayle
@alisyngayle.bsky.social · Bluesky

Chase Hughes - “Update On My Brain Disease” youtu.be/W4tXqcXeHHM?...

Sep 30, 2025 View post →
Sheri Geddygirl Beri
@Sheri_Beri_2112 · X

Very insightful ~ check itout Update On My Brain Disease https://t.co/r54VRjgW18 via @YouTube

Sep 28, 2025 · 1,461 followers View post →
Americo Ramos
@samissomar · X

The stuff they don't want you to know,they hide it...remember big pharma Industrial complex is really a business,they profit from maintaining the diseases !... https://t.co/MLoT0NJkPl

Sep 26, 2025 · 165 followers View post →
Truth has no Agenda
@4_TruthFreedom · X

Update On My Brain Disease https://t.co/UwpPu0msgR

Sep 23, 2025 · 1 like · 191 followers View post →
OneWildRide 377
@Onewildride3 · X

https://t.co/cxRew05urH

Sep 19, 2025 · 54 followers View post →
Ricky Formby
@FormbyRicky · X

https://t.co/CgvshZQyUE

Sep 19, 2025 · 4,271 followers View post →
Vigilante
@VigilanteSystem · X

Update On My Brain Disease https://t.co/un8J4lZmOn via @YouTube

Sep 19, 2025 · 518 followers View post →
Phil Joyner
@JoynerPhil53773 · X

Update On My Brain Disease https://t.co/x9LM5UI097 via @YouTube

Sep 18, 2025 · 194 followers View post →
Brittanie Fellows
@BrittFellows · X

https://t.co/wZiBTX7I5O

Sep 17, 2025 · 109 followers View post →
Leonard Haglund
@HaglundLeo76751 · X

Update On My Brain Disease https://t.co/kF0q7XgTJW via @YouTube Methylene Blue, how do you do ?

Sep 16, 2025 · 40 followers View post →
Susannah
@Be_Observant1 · X

The wonders of methylene blue https://t.co/dlhfXtTM1A via @YouTube

Sep 16, 2025 · 886 followers View post →
via_lila_m
@via_lila_m · X

@SteveVenright stumbled on this, and holy shit! this is so good to see(if you’re interested in health optimization at all.) : https://t.co/hhNVeoOunb

Sep 16, 2025 · 1 like · 526 followers View post →
Eileen Fitzgerald Keane
@E_KeaneKeane · X

https://t.co/Mh501vyZlx

Sep 16, 2025 View post →
Catherine
@Catherine212231 · X

https://t.co/MQNGCVYxQu

Sep 15, 2025 · 640 followers View post →
Yvonne Wagner
@YvonneWagn8830 · X

https://t.co/qohS4NlzIB

Sep 15, 2025 · 1 like · 6,087 followers View post →
Alisa
@digitalpaybiz · X

A must watch!https://t.co/RJhXa6xvvY

Sep 15, 2025 · 14 followers View post →
BDJ
@BDJ95812629 · X

Update On My Brain Disease https://t.co/akRIDFzRc4 via @YouTube

Sep 14, 2025 · 13 followers View post →
Linda Cosy
@lindacosylife · X

Update On My Brain Disease https://t.co/SItiW6NLDh via @YouTube

Sep 13, 2025 · 10,454 followers View post →
K
@KarylMarlow · X

Update On My Brain Disease https://t.co/yThrOboFWv via @YouTube

Sep 13, 2025 · 323 followers View post →
Shawn Craig
@shawniefc · X

‼️NEURO BRAIN DISEASE MIRACLE‼️ ‼️CHASE HUGHES ‼️ METHYLENE BLUE, RED LIGHT, BEET ROOT ETC.‼️ Update On My Brain Disease https://t.co/HDp5pfnjfS via @YouTube

Sep 13, 2025 · 795 followers View post →
Iliana Ingram
@Ingram_Iliana · X

https://t.co/atf2kMABqq

Sep 12, 2025 · 125 followers View post →
Tony Garcia
@TonyTollerson · X

Update On My Brain Disease https://t.co/scsFxZwJu2 via @YouTube

Sep 11, 2025 · 6 followers View post →
Ed C.
@n7ekg · X

I keep hearing really good things about Methylene Blue: https://t.co/buC5wLRQmu

Sep 10, 2025 · 2,298 followers View post →
ChristinA Nickerson
@newlifeevergeen · X

Update On My Brain Disease https://t.co/Vlb1Yx7Xl2 via @YouTube

Sep 7, 2025 · 1,665 followers View post →
Neil
@Neiltastic555 · X

https://t.co/bKUn36QYry

Sep 6, 2025 · 12 followers View post →
Mike Man
@mikeman4w · X

All the stuff I would’ve scarfed at… Couldn’t be more of a true statement Update On My Brain Disease https://t.co/3grp61peSB via @YouTube

Sep 2, 2025 · 1 like · 3,513 followers View post →
Annie Ruler
@RulerAnnie · X

Update On My Brain Disease https://t.co/Me5qVqY1y7 via @YouTube

Aug 31, 2025 · 77 followers View post →
Karina Demurchyan
@MyRealtorKarina · X

@Raindropsmedia1 https://t.co/pLL1YqhPFt

Aug 29, 2025 · 768 followers View post →
Mickey Pittman
@MickeyPittman · X

Learn from this survivor//Update On My Brain Disease https://t.co/MMWSrINrOb via @YouTube

Aug 26, 2025 · 2 likes · 551 followers View post →
VotExpress
@vehicle4miracle · X

Update On My Brain Disease https://t.co/JKk0p7ChT6 via @YouTube

Aug 25, 2025 · 221 followers View post →
Holographic
@hyp3rlexic · X

@Juliesnark1731 Hi Julie... please watch these two videos: https://t.co/OzgbzixVwW https://t.co/bColvite6G Take particular note of the "show more" info of the second video (Dr. John Lieurance)... there may be some clues or leads for you for further investigation.

Aug 21, 2025 · 1 like · 249 followers View post →
Barbara Jean, BL
@BarbaraYoulio · X

Update On My Brain Disease https://t.co/lSvodJ73bw via @YouTube Chase Hughes, and his journey. This was posted on YouTube, ten months ago and is fascinating.

Aug 20, 2025 · 189 followers View post →
Who? Me
@whatever77200 · X

Blue is the jam for brain injury

Aug 13, 2025 · 1 like · 156 followers View post →
Mr.E
@idk7idk7 · X

https://t.co/5X3jkFZx4e

Aug 13, 2025 · 71 followers View post →
reita presley
@Hedeshar · X

RT @Hedeshar: Update On My Brain Disease https://t.co/t7cWnzlQDo via @YouTube 18 mins 45 secs

Aug 5, 2025 · 1 share · 50 followers View post →
reita presley
@Hedeshar · X

Update On My Brain Disease https://t.co/t7cWnzlQDo via @YouTube 18 mins 45 secs

Aug 5, 2025 · 1 like · 1 share · 50 followers View post →
Flat Earth Effect
@FlatEarthEffect · X

https://t.co/w3N7SNlsAn

Jul 31, 2025 · 15,229 followers View post →
Nicole Snow
@tempusviators · X

Update On My Brain Disease https://t.co/VkEQ3eq4NU via @YouTube

Jul 28, 2025 · 2,066 followers View post →
Joseph Emmanuel Torres II
@julechtan · X

Update On My Brain Disease https://t.co/r8uMBeWDI9

Jul 27, 2025 · 172 followers View post →
Lucy, nurse for the people not profits.
@LucciaorLucy · X

@7SEES_ You should look up Chase Hughs. He has neurological issues and was given a protocol that changed his life. He has a video on YT about it and I believe his website. https://t.co/SOZbUoIBjC

Jul 17, 2025 · 6 likes · 1 share · 8,953 followers View post →
Jenni Levine
@LevineJenni · X

Update On My Brain Disease https://t.co/n05JJkeYpK via @YouTube

Jul 14, 2025 · 13 followers View post →
Jenni Levine
@LevineJenni · X

Update On My Brain Disease https://t.co/HMSdPweQww via @YouTube My brain was very sick for a number of years, I was ready for a trip to Switzerland if the decline continued as no doctor could help. There is so much we can do, don't give up!

Jul 11, 2025 · 13 followers View post →
Jenni Levine
@LevineJenni · X

Update On My Brain Disease https://t.co/x2Gsj7uo16 via @YouTube

Jul 11, 2025 · 13 followers View post →
Russ
@RJnovaTwiter · X

https://t.co/L6qAA9TAEk

Jul 9, 2025 · 337 followers View post →
Peppermint Patti
@Angelsgal02 · X

Just looking into this. It sounds like it could help many people who suffer from neuro problems, etc. Chase Huges https://t.co/chpSBrg6gQ

Jul 5, 2025 · 4,262 followers View post →
Karl Bushnell
@ka89295 · X

https://t.co/kmuaPy5g88

Jul 3, 2025 · 70 followers View post →
The Secret Corridor
@SecretCorridor · X

@crystalandqueue @TheQuartering If you want to learn more listen to this: https://t.co/itzRttsWub. As for long-term studies, this treatment has been around since 1876 and studied extensively. That doesn't mean you shouldn't be cautious, but know there is more to this than you know.

Jul 3, 2025 · 1 like · 875 followers View post →
The Secret Corridor
@SecretCorridor · X

@TheQuartering It was already making noise before RFK Jr's endorsement. I would argue it is this man who has done more to raise awareness. This treatment has been around for decades and studied extensively, but yes, always research more . Chase Hughes: @NCIUniversity https://t.co/itzRttsWub

Jul 3, 2025 · 875 followers View post →
The Secret Corridor
@SecretCorridor · X

Still the best intro to Methylene Blue I've found to date: https://t.co/itzRttsoED Do you know better? Let me know in the comments (asking for all my friends & family) #methyleneblue

Jun 28, 2025 · 875 followers View post →
Dawn Style
@SteilVerch · X

Update On My Brain Disease https://t.co/5Ur1DzRvIf via @YouTube Methylene Blue Beer Root Powder And “We are Nature.” Loved it.

Jun 26, 2025 · 1,339 followers View post →
Dr ₿ ✝️⚡️
@DocMcJ · X

@angelsfly_143 Prayers, so difficult. I just watched this https://t.co/MUCu1P6Btl About a gentleman who used methylene blue to heal his brain from seizures

Jun 21, 2025 · 3 likes · 3,185 followers View post →
Maximum Weeb Bronze Age Autist
@rajm2016 · X

Update On My Brain Disease https://t.co/6ssZANvqWx via @YouTube

Jun 21, 2025 · 3,269 followers View post →
Maximum Weeb Bronze Age Autist
@rajm2016 · X

Update On My Brain Disease https://t.co/TQyvQkCuV4 via @YouTube

Jun 21, 2025 · 3,269 followers View post →
John Taylor
@JoTa_nchi14960 · X

https://t.co/jnndnI402J

Jun 20, 2025 · 1,021 followers View post →
TheKasstle
@TheKasstle · X

Update On My Brain Disease

Jun 19, 2025 · 1 like · 6,099 followers View post →
GramzSchitZnGiggleZ
@GramZSchitZ · X

This is An Amazing Testimonial & it Supports My Belief that "Nature's Medicine Cabinet" is Hands Down Better than what the Pharmaceutical Companies are Selling! https://t.co/ZkTAIe7X7J

Jun 17, 2025 · 1,120 followers View post →
Susan Griffith
@su163264 · X

Update On My Brain Disease https://t.co/GpmzOqGyRg via @YouTube

Jun 16, 2025 · 1 like · 109 followers View post →
Barbara Jean, BL
@BarbaraYoulio · X

Update On My Brain Disease https://t.co/rRdz9HYrUX via @YouTube Wow! I never knew this about Chase Hughes. This video is amazing, about what he went through most of his life.

Jun 11, 2025 · 189 followers View post →
Ke-Covan'iel
@jahwatar · X

https://t.co/a9koxrHjnv

Jun 11, 2025 · 105 followers View post →
Beedo
@beedo1973 · X

https://t.co/5rt9eJaMHV

Jun 3, 2025 · 2 followers View post →
john macker
@johnmacker12 · X

Update On My Brain Disease https://t.co/StYUxnfcqC via @YouTube

Jun 2, 2025 · 263 followers View post →
John
@whodwhoooo · X

Update On My Brain Disease https://t.co/pFmT2ZJjsr via @YouTube

May 31, 2025 · 210 followers View post →
Rufus The Pelican
@PelicanRuf13997 · X

@DrNeilStone It boosts mitochondrial health. This neurologist cured temporal lob epilepsy with methylene blue: https://t.co/BDCP6oY1hq Many psychologists discuss in YouTube how they help ADHD patients with it. It is only thing that really worked with my depression.

May 30, 2025 · 108 followers View post →
Tobie Venne
@Tobie27261294 · X

https://t.co/I74xegQBIf

May 29, 2025 · 340 followers View post →
Meri Perkins
@mlperk1 · X

Mitochondria: Update On My Brain Disease https://t.co/fjvt079tER via @YouTube

May 29, 2025 · 1,294 followers View post →
Clutch Allsup
@EpiphanyBob · X

Update On My Brain Disease https://t.co/n1C39Bik07 via @YouTube

May 23, 2025 · 74 followers View post →
Grumpy Old Medina
@TrustNoWun · X

@jakeshieldsajj Have you ever researched 'methylene blue'? Chase Hughes did a video on YT about it helping with his brain disease. It might be worth a try. God bless. Here's Chase's video: https://t.co/tYQdQ3U78T

May 22, 2025 · 304 followers View post →
ProudScouse76
@ProudScouse76 · X

@realpeteyb123 Have you checked this out? https://t.co/zEsh9FKKgl

May 20, 2025 · 2,691 followers View post →
DAVID BROYLES
@DAVEROXXXX · X

https://t.co/wWb4zfXuhl

May 19, 2025 · 940 followers View post →
DAVID BROYLES
@DAVEROXXXX · X

https://t.co/wWb4zfXuhl

May 19, 2025 · 940 followers View post →
Shane
@tShaneB123 · X

Update On My Brain Disease https://t.co/sWARNR73W3 via @YouTube

May 18, 2025 · 96 followers View post →
Raena Kim-Geyer
@RaenaKimGeyer · X

Is Methylene blue THE ‘magic bullet’? What we thought was fringe, turns out it has basis in actual science. He has degrees is neurosciences and radiology so he almost dismissed this. It saved his life. Update On My Brain Disease https://t.co/XGvM0SfrYv via @YouTube

May 16, 2025 · 1 like · 198 followers View post →
Bella
@Bella89621145 · X

https://t.co/lO29IV2Eud

May 15, 2025 · 1,163 followers View post →
Hemlock Dreams
@AHewitt973255 · X

Update On My Brain Disease https://t.co/K92Jx4K9S6 via @YouTube This is fascinating. Methylene blue. Why aren't Drs talking about it. This is a personal journey recorded.

May 15, 2025 · 809 followers View post →
¥€$2Truth
@PlukRo73148 · X

How Methylene Blue helped - "Update On My Brain Disease" https://t.co/e7uf5HSorI

May 14, 2025 · 359 followers View post →
Wallace Sr Donegan
@sr_donegan34121 · X

https://t.co/v8QbJplyye Wonderful share

May 13, 2025 · 393 followers View post →
Jamey Peltonen
@pelt1980 · X

Update On My Brain Disease https://t.co/QIvurSoyDA via @YouTube methylene blue

May 10, 2025 · 1 like · 7,502 followers View post →
Rose Smith
@RoseSmi92658522 · X

https://t.co/CGw49A0U89

May 9, 2025 · 1 like · 4,139 followers View post →
Nadine
@Nadine25667514 · X

@cafelockedout Take a Quick Look at this recovery protocol. I know it’s his heart and body but part of the body is also the brain. Might give some good healing tips. ❤️ https://t.co/cfxjiP5Dzs

May 9, 2025 · 1 like · 141 followers View post →
Rose Smith
@RoseSmi92658522 · X

https://t.co/279dx80Yuj

May 5, 2025 · 1 like · 4,139 followers View post →
Rose Smith
@RoseSmi92658522 · X

https://t.co/KBB8thNf3S

May 5, 2025 · 4,139 followers View post →
Esmeralda ❤️
@moestuingirl · X

@jimstewartson Dr Phil budy is grifting this https://t.co/qun8Dl8tBR

Apr 23, 2025 · 298 followers View post →
17WaysFromSunday
@17WaysFrSunday · X

@8traq_truth I have been a fan of Chase Hughes for a few years now specifically regarding his work on the Behavior Panel. Seems to be a pretty down to earth guy, and is a military veteran. https://t.co/gmtqlXpFLk

Apr 22, 2025 · 5 likes · 1 share · 5,399 followers View post →