Aliment Pharmacol Ther July 2005 PMID 15963081

Omeprazole delays gastric emptying in healthy volunteers: an effect prevented by tegaserod.

G Tougas, D L Earnest, Y Chen, C Vanderkoy, M Rojavin

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Abstract in brief

Omeprazole, a proton pump inhibitor used for acid reflux, can delay gastric emptying in healthy individuals, but taking tegaserod with it can prevent this delay.
The study involved 40 healthy male volunteers who took omeprazole and either tegaserod or a placebo for 14 days; gastric emptying was measured before and after treatment.
Results showed that omeprazole alone slowed gastric emptying, but when combined with tegaserod, this effect was prevented, and the combination was safe and well tolerated.]

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