#Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinated with the physiology & its practical implications. https://t.co/uZnRAbxqjI @TStellingwerff @LouiseMBurke @JohnAHawley @LSpriet #cycling #keto #sportsnutrition https://t.co/eRbW1sNm3T
Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration.
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May 2019 – Jan 2025Where it's discussed
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X / Twitter40 posts
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Facebook6 posts
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YouTube5 videos
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What people are saying
Discussions frequently emphasize the physiological implications of the research, with posts mentioning decreased PDH activity and glycogenolysis after fat adaptation, reflecting a thorough engagement with the mechanisms involved. Words like 'fascinate,' 'must read,' and references to historical figures imply a high level of interest and recognition of the study's importance, which collectively suggest that the findings could influence future research and athletic practices.
Most comments agree that fat adaptation affects muscle metabolism, specifically noting decreased PDH activity and glycogenolysis, with some discussing whether this compromise impacts exercise performance.
Discussions reflect high interest, with users referencing specific studies, historical discussions, and inviting further reading, showing curiosity about physiological mechanisms.
Many posts delve into detailed physiological interpretations, citing references and historical contexts, demonstrating deep engagement with the research.
While some recognize the significance of these metabolic shifts for athletic performance and training strategies, others suggest the findings might challenge existing paradigms or be relevant for practical athletic applications, indicating noticeable pote
Abstract in brief
- The study investigates how five days on a high-fat diet followed by carbohydrate restoration affects fuel use during exercise, finding increased fat oxidation and decreased carbohydrate oxidation after fat adaptation.
- Muscle enzyme activities related to carbohydrate metabolism, such as PDH, were lower in the fat-adapted state, leading to reduced glycogen breakdown during exercise.
- These changes suggest that fat adaptation with carbohydrate restoration shifts muscle fuel utilization toward more fat burning and less carbohydrate use during aerobic activities.]
Top posts
Most liked on X and BlueskyTks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact on decreasing CHO oxidation paper. I was a young nervous PhD student w/ @JohnAHawley @LouiseMBurke @LSpriet Hargreaves and Watt (& Jack!). https://t.co/lL8PC4NcaO https://t.co/zPfsUtmDwR
Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had been restored. Are we taking away gears 5&6 with chronic low-carb diets? @TStellingwerff @LouiseMBurke #Coaches20 https://t.co/S2sV4BjfDS
@ProfTimNoakes @LoreofRunning1 @DoctorTro @AKoutnik @RafaelPasschier @timpodlogar @mike_williams73 @DrBSteamjets @jp_walhin @campbellmenz @AaronHengist @theplews1 Its possible that ATP is defended so tightly that the capacity for high intensity exercise is limited in a scenario where the resythesis rate is suboptimal. It would be consisted with yours and others data https://t.co/X2YTPfjjql https://t.co/G6KaqBrX7z
Did @TStellingwerff discuss https://t.co/2sONGDGVoL in which hi-fat diet altered metabolism without altering exercise performance (p385). Thus correct title:"Decreased PDH activation and glycogenolysis during exercise following fat adaptation DOES NOT IMPAIR EXERCISE PERFORMANCE" https://t.co/cuN4Q3HHqD
@AthIllustrated @TStellingwerff @LouiseMBurke @ACSMNews @JohnAHawley @LSpriet Should be able to download it for free from @AJPEndoMetab Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration https://t.co/w0zefxeCrZ
All mentions
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@ProfTimNoakes @LoreofRunning1 @DoctorTro @AKoutnik @RafaelPasschier @timpodlogar @mike_williams73 @DrBSteamjets @jp_walhin @campbellmenz @AaronHengist @theplews1 Its possible that ATP is defended so tightly that the capacity for high intensity exercise is limited in a scenario where the resythesis rate is suboptimal. It would be consisted with yours and others data https://t.co/X2YTPfjjql https://t.co/G6KaqBrX7z
Did @TStellingwerff discuss https://t.co/2sONGDGVoL in which hi-fat diet altered metabolism without altering exercise performance (p385). Thus correct title:"Decreased PDH activation and glycogenolysis during exercise following fat adaptation DOES NOT IMPAIR EXERCISE PERFORMANCE" https://t.co/cuN4Q3HHqD
La piruvato deshidrogenasa se ve comprometida después del aumento de grasas en la alimentación
@kevtharris @MPattersonRD @AlexJLeaf @JamesyMorton @close_nutrition https://t.co/HgCZpSrl5G
RT @jwhitfie: @AthIllustrated @TStellingwerff @LouiseMBurke @ACSMNews @JohnAHawley @LSpriet Should be able to download it for free from @AJ…
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
@AthIllustrated @TStellingwerff @LouiseMBurke @ACSMNews @JohnAHawley @LSpriet Should be able to download it for free from @AJPEndoMetab Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration https://t.co/w0zefxeCrZ
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
RT @TStellingwerff: Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact o…
Tks @LouiseMBurke for sending & taking this photo ~20 yrs ago at @ACSMNews: discussing the fat adaptation/keto impact on decreasing CHO oxidation paper. I was a young nervous PhD student w/ @JohnAHawley @LouiseMBurke @LSpriet Hargreaves and Watt (& Jack!). https://t.co/lL8PC4NcaO https://t.co/zPfsUtmDwR
@B_Holmer @vincentninja68 2/2 Check references for more reading if you're keen. https://t.co/DebFySfGye https://t.co/bdwguKCUEx
@jlAreta @HermanPontzer @SamueleMarcora @sweatscience Maybe this work is relevant in this context https://t.co/7qChNn3Mz1 .. I need to read the actual old paper though...
@ForTkdi @shashiiyengar @ProfTimNoakes @PeterBrukner @LouiseMBurke And this: 2006 Stellingwerff Hawley Burke Decreased PDH activation and glycogenolysis during exercise following fat adaptation with carbohydrate restoration https://t.co/63tg2ANq0r
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
RT @cashford_: Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had be…
Just five days of a low-carb, high fat diet caused a significant decrease in PDH activity, even after glycogen levels had been restored. Are we taking away gears 5&6 with chronic low-carb diets? @TStellingwerff @LouiseMBurke #Coaches20 https://t.co/S2sV4BjfDS
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
RT @guzmannutrition: #Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinate…
#Study on fat adaptation followed by high carbohydrate intake; a must read if you’re working with #athletes. Fascinated with the physiology & its practical implications. https://t.co/uZnRAbxqjI @TStellingwerff @LouiseMBurke @JohnAHawley @LSpriet #cycling #keto #sportsnutrition https://t.co/eRbW1sNm3T