January 2006 PMID 16393666

The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance.

Paloma Alonso-Magdalena, Sumiko Morimoto, Cristina Ripoll, Esther Fuentes, Angel Nadal

Mentions

16
Peak: 2 in May 2019
across 5 sources since Oct 2017

Extended reach

127,517
potential audience

Total likes

5,394

Video views

121,578

Mentions per month

Oct 2017 – Jun 2024

Where it's discussed

  • Facebook5 posts
  • X / Twitter4 posts
  • Blogs3 articles
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The discussions strongly agree with the findings, citing previous research from 2006 and emphasizing the significance of BPA's role in disrupting pancreatic function, which underscores their recognition of the study's importance. The tone is both respectful and enthusiastic, using words like 'important studies' and 'celebrate,' reflecting high interest and perceived relevance in the scientific community.

AgreementStrong agreement

Most discussions refer positively to the research, emphasizing its importance and relevance, with some referencing prior findings to reinforce agreement.

InterestHigh interest

Participants demonstrate high engagement with detailed mentions of experimental results, historical context, and significance of the findings.

EngagementModerate engagement

Posts show active involvement through citations of studies, celebration of research milestones, and referencing influential figures, indicating thoughtful engagement.

ImpactHigh impact

Discussions highlight the study's potential to influence policy and understanding of environmental contributors to metabolic disorders, suggesting high perceived impact.

Abstract in brief

  • The study shows that bisphenol A (BPA), an environmental contaminant that mimics estrogen, can quickly lower blood sugar levels and increase insulin release in mice, affecting pancreatic beta-cell function.
  • Prolonged exposure to BPA or estrogen (E2) leads to increased insulin content in the pancreas and can cause chronic high insulin levels, which eventually impair glucose and insulin regulation, suggesting a risk for developing insulin resistance.
  • These findings demonstrate that environmental estrogens like BPA may contribute to metabolic disorders such as type 2 diabetes, hypertension, and dyslipidemia by disrupting normal hormone and glucose regulation processes.

Top posts

Most liked on X and Bluesky
Tim Rees
@NutritionalThe3 · X

Mice exposed to BPA 1000x

Oct 31, 2022 · 8 likes · 4,918 followers View post →
Diabetes Research Unit - UMH
@UnibadUMH · X

To celebrate Paloma's Medal of Honor, our #TBT shows one of her most important studies: "The estrogenic effect of #bisphenol A disrupts #pancreatic beta-cell function in vivo and induces #insulin resistance", published in @EHPonline, 2006. (1/6) https://t.co/IqPbdAb2u0 https://t.co/GV7Xti6Hr3

May 16, 2019 · 2 likes · 1 share · 325 followers View post →
Diabetes Research Unit - UMH
@UnibadUMH · X

@HEEDSorg @AmDiabetesAssn @US_FDA @EPA We published the same in mice in 2006. Four days treatment with BPA induced insulin resistance. @Am https://t.co/Iq52Ta8dYW

Jun 27, 2024 · 1 like · 325 followers View post →
ASDIBUR
@AsdiburBurgos · X

RT @UnibadUMH: To celebrate Paloma's Medal of Honor, our #TBT shows one of her most important studies: "The estrogenic effect of #bisphenol…

May 17, 2019 · 1 share · 368 followers View post →

All mentions

Diabetes Research Unit - UMH
@UnibadUMH · X

@HEEDSorg @AmDiabetesAssn @US_FDA @EPA We published the same in mice in 2006. Four days treatment with BPA induced insulin resistance. @Am https://t.co/Iq52Ta8dYW

Jun 27, 2024 · 1 like · 325 followers View post →
Tim Rees
@NutritionalThe3 · X

Mice exposed to BPA 1000x

Oct 31, 2022 · 8 likes · 4,918 followers View post →
ASDIBUR
@AsdiburBurgos · X

RT @UnibadUMH: To celebrate Paloma's Medal of Honor, our #TBT shows one of her most important studies: "The estrogenic effect of #bisphenol…

May 17, 2019 · 1 share · 368 followers View post →
Diabetes Research Unit - UMH
@UnibadUMH · X

To celebrate Paloma's Medal of Honor, our #TBT shows one of her most important studies: "The estrogenic effect of #bisphenol A disrupts #pancreatic beta-cell function in vivo and induces #insulin resistance", published in @EHPonline, 2006. (1/6) https://t.co/IqPbdAb2u0 https://t.co/GV7Xti6Hr3

May 16, 2019 · 2 likes · 1 share · 325 followers View post →