After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO BENEFITS in CHD, CVD etc, despite lower LDL levels. In fact, control group did better. (higher LDL) https://t.co/6mbqAkTkRe
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial.
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Jun 2019 – Oct 2025Where it's discussed
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News66 articles
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AI synopsis
What people are saying
Several discussions reference the surprising outcome that reducing fat did not lower cardiovascular risks, with posts criticizing the study for its focus on LDL levels and emphasizing that 'control group did better.' The tone varies from skeptical to analytical, with some posts citing specific data and others questioning the study's implications for dietary guidelines, demonstrating a high interest and critical engagement overall.
The discussions display mixed reactions, with some posts questioning the validity of the findings, while others acknowledge the study's rigorous design but express surprise at the results.
Posts show high interest, illustrated by references to detailed studies, mentions of specific data, and critical analysis, indicating active engagement with the research.
Many comments delve into methodological critiques, cite related studies, and debate dietary fat's role, reflecting a moderate level of deep critical engagement.
The overall tone suggests the study has a notable impact, challenging existing dietary beliefs and prompting widespread controversy and discussion in the community.
Abstract in brief
- This study tested whether a low-fat diet high in vegetables, fruits, and grains could reduce the risk of cardiovascular disease in postmenopausal women, based on long-term data from the Women's Health Initiative.
- Results showed that after six years, women in the intervention group significantly reduced their fat intake and slightly increased their consumption of healthy foods, leading to improvements in some health markers like LDL cholesterol, blood pressure, and factor VIIc, but did not significantly change HDL cholesterol, triglycerides, glucose, or insulin levels.
- Despite these dietary changes and risk factor improvements, there was no significant reduction in the actual rates of coronary heart disease, stroke, or combined cardiovascular events between the intervention and comparison groups over the follow-up period.
Top posts
Most liked on X and Bluesky@DrAndyGalpin These are the "go-to" for omega-6 human interventions with poor outcomes. All have pretty major flaws. https://t.co/Qpgr5Urvqa https://t.co/UlGzbCAyv9 https://t.co/Mh8YN0upOO https://t.co/9HiucR9S3D
@G2172909963 @drtejallathia @saaiyer @shashiiyengar Humans became human by eating meats ! There are ZERO dietary essential carbohydrates needed in the human diet ! https://t.co/jHQSZRw43j ➡️ https://t.co/sCCJokqK8z ➡️ https://t.co/jJHXBYJDgv ➡️ https://t.co/yUCwWzOruY➡️ https://t.co/OE8ND8RIw3 ➡️ https://t.co/PYVM93ZBej
>to find a mean fat intake reduction of 8.2%, then said they CVD effects were “modest”. Of course they were. Your participants didn’t meet the basic requirement of your testing goal. CVD study: https://t.co/ewijMUmxgi Weight loss study: https://t.co/amKavHyqit >
@grok @MasalaFry69 @boycrazystacy2 Lowering saturated fat lead to an increased rate of heart disease by 47% to 61%. https://t.co/5S3tUpOZ2C https://t.co/DxUWbvhovm https://t.co/LdVy2wftxr https://t.co/ubFrZel0Bf
@JTayScience @REV_Insulin_Res Star Trek logical thinking -10 Argumentum Ad Vercundiam ( Appeal to Authority) https://t.co/9kZTiN2JHC ➡️ https://t.co/Gj5p60eltr ➡️https://t.co/oB2oR4MYHq ➡️ https://t.co/yUCwWzOruY ➡️ https://t.co/zJCNwDFVgb
All mentions
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@fenixlarare https://t.co/kwkiqdBgiB https://t.co/hnk03nn4yt https://t.co/BbLxQy5R2L https://t.co/VnJRHZ4MoH https://t.co/UCxcLvr7wm https://t.co/doHRIGRjbv
@grok @MasalaFry69 @boycrazystacy2 Lowering saturated fat lead to an increased rate of heart disease by 47% to 61%. https://t.co/5S3tUpOZ2C https://t.co/DxUWbvhovm https://t.co/LdVy2wftxr https://t.co/ubFrZel0Bf
@hblwebb @AMPajari "En animalisk kost kan också innehålla ... onödigt mycket mättat fett" (@AMPajari). Hm, på riktigt
@johansvensson82 @arlasverige Ja, de har väl blandat i rapsolja? Det borde ingen äta. Smör och andra animaliska fetter är bra för fysisk och mental hälsa (Ede, 2019) https://t.co/8cnkxeYvUp (Howard et al 2006) https://t.co/2VdQfDHJ8T
@FearZero4 @CarnivoreDad @skydog576 @SBakerMD 2 largest-ever NIH-funded, RCTs, concluded that sat fats had no effect on cardiovascular mortality or total mortality. A 2016 analysis shows 22% higher risk for each 30 mg/dL reduction in serum cholesterol. https://t.co/kvrLK71eEe https://t.co/UpEQUhnPX2 https://t.co/ooUoRPm8DX
@Tellit007 @SamaHoole Many studies to show there's little to no concern with consuming animal products (meat or fat) and LDL https://t.co/gZuj1i6TEg https://t.co/EU10ASP73H https://t.co/jOf1nJYdWu https://t.co/7JxO5vQNjx https://t.co/lbVYVog484 https://t.co/fWeyIXcd7u https://t.co/AHlnUrPfpo
@JTayScience @REV_Insulin_Res Star Trek logical thinking -10 Argumentum Ad Vercundiam ( Appeal to Authority) https://t.co/9kZTiN2JHC ➡️ https://t.co/Gj5p60eltr ➡️https://t.co/oB2oR4MYHq ➡️ https://t.co/yUCwWzOruY ➡️ https://t.co/zJCNwDFVgb
“癌を減らすために低脂肪で野菜、果物、穀物を多く含むことを目的とした食事が心血管疾患のリスクを減らすという仮説を検証すること。" 低脂肪の食事パターンと心血管疾患のリスク:女性の健康イニシアチブのランダム化比較試験 #赤身肉 #ヴィーガン #vegan #菜食 #癌 https://t.co/fniNrkn4NN
@PlantsRunning @KenDBerryMD A single case if true means nothing since it states nothing about confounders ! 1️⃣ https://t.co/jHQSZRw43j 2️⃣ https://t.co/3ePbh9nWlX 3️⃣ https://t.co/zTL6p84Em4 4️⃣ https://t.co/Gw4pI71cIg 5️⃣ https://t.co/Gj5p60eltr 6️⃣ https://t.co/oB2oR4MYHq 7️⃣ https://t.co/yUCwWzOruY
@G2172909963 @drtejallathia @saaiyer @shashiiyengar Humans became human by eating meats ! There are ZERO dietary essential carbohydrates needed in the human diet ! https://t.co/jHQSZRw43j ➡️ https://t.co/sCCJokqK8z ➡️ https://t.co/jJHXBYJDgv ➡️ https://t.co/yUCwWzOruY➡️ https://t.co/OE8ND8RIw3 ➡️ https://t.co/PYVM93ZBej
>to find a mean fat intake reduction of 8.2%, then said they CVD effects were “modest”. Of course they were. Your participants didn’t meet the basic requirement of your testing goal. CVD study: https://t.co/ewijMUmxgi Weight loss study: https://t.co/amKavHyqit >
@TylerCartwright @mosca_matthew @BiggestComeback @NutritionMadeS3 No the official dietary guidelines and the background dietary advise has been proven to be wrong and based on lies . Paid the price never again ! I do what I’ve subjected to my own testable hypothesis to see if it valid . https://t.co/oB2oR4MYHq ➡️ https://t.co/yUCwWzOruY
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial - PubMed https://t.co/4ztOHv1pLW
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
RT @NutritionalThe3: After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO…
After +8 years of a low(er) fat, higher fruits, vegetables & grains diet, the intervention group (n=19541) showed NO BENEFITS in CHD, CVD etc, despite lower LDL levels. In fact, control group did better. (higher LDL) https://t.co/6mbqAkTkRe
- Women’s Health Initiative, a dietary intervention to test low-fat diet with cancer and CVD risks found no association between replacement of SF with carbohydrates https://t.co/jpJ1JV3gVM
@DrAndyGalpin These are the "go-to" for omega-6 human interventions with poor outcomes. All have pretty major flaws. https://t.co/Qpgr5Urvqa https://t.co/UlGzbCAyv9 https://t.co/Mh8YN0upOO https://t.co/9HiucR9S3D
@Gearoidmuar @ZahcM @Michalski_MC @fleroy1974 @WHO https://t.co/LdSKCNmA4R These results ? https://t.co/7OgPp09L3i
Low-Fat Dietary Pattern and Risk of Cardiovascular Disease : The Women's Health Initiative Randomized Controlled Dietary Modification TrialJAMA ,295(6):629-642. 643-654. 655-666.