Premature ageing prevention: limitations and perspectives of pharmacological interventions.

Abstract in brief

• The text discusses the increasing aging population in developed countries and the related rise in age-associated diseases like cardiovascular issues, neurodegeneration, cancer, and diabetes, emphasizing the need for effective prevention methods.
• It reviews current pharmacological approaches thought to slow aging, such as antidiabetic drugs, hormones, antioxidants, and neurotropic drugs, but notes that most studies do not convincingly prove these interventions can extend lifespan or are safe.
• The authors suggest establishing an international program for expert evaluation of potential anti-aging interventions, aiming to assess various chemical, immunological, dietary, and behavioral strategies to promote health and lifespan extension, aiding global health policies.