PubHawk
July 2007 PMID 17615391

Physiology and neurobiology of stress and adaptation: central role of the brain.

Bruce S McEwen

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Mentions

80
Peak: 16 in Jul 2025
across 6 sources since Jun 2019

Extended reach

519,017
potential audience

Total likes

25,947

Video views

458,652

Mentions per month

Jun 2019 – Nov 2025

Where it's discussed

  • X / Twitter25 posts
  • YouTube25 videos
  • News12 articles
  • Facebook11 posts
  • Blogs5 articles
  • Reddit2 posts

AI synopsis

What people are saying

Discussions highlighted the significance of the brain's role in handling stress, with posts referencing terms like 'toxic shame' and 'chronic stress' along with phrases like 'VERY IMPORTANT VIDEO!!!!!!!' which indicates urgency and importance. The tone in some posts was reflective, such as comments about personal experiences with numbing feelings, while others cited references to studies, demonstrating a blend of academic interest and personal insights in addressing how chronic stress affects health. Overall, the choice of language and context reinforces a collective eagerness to explore and understand stress's impact, noting both scientific findings and personal anecdotes.

AgreementModerate agreement

Most discussions show a general alignment with the views presented in the publication, though there are some differing opinions.

InterestHigh interest

The topics raised about stress and its effects on the brain sparked a high level of curiosity, as participants sought to understand the implications better.

EngagementModerate engagement

Some posts referenced specific studies and findings, indicating a moderate level of depth in the discussions.

ImpactHigh impact

Users perceive the article's insights on stress and brain function as having significant relevance and influence on both personal and broader health practices.

Abstract in brief

  • The brain is central to how we perceive and respond to stress, influencing both our physical and behavioral reactions, which can be beneficial or harmful.
  • Stress triggers communication between the brain and other body systems, leading to both acute responses (like fight-or-flight) and chronic stress, which accumulates over time and can damage health.
  • Key brain areas, such as the hippocampus, are affected by stress hormones, shaping our emotional responses and overall health, but interventions like exercise and social support can help mitigate the effects of chronic stress.
Read the full abstract

Top posts

Most liked on X and Bluesky
tiffymLuv
@tiffymLuv · X

Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 13, 2025 · 11 likes · 5 shares · 827 followers View post →
Todd Hargrove
@ToddHargrove · X

Related: “the brain … is the key organ of the stress response because it determines what is threatening and, therefore, stressful and also controls the behavioral and physiological responses to potentially stressful experiences.” — Bruce McEwen https://t.co/eLtZuLVlJ5

Jun 3, 2019 · 7 likes · 3 shares · 4,729 followers View post →
Dr Kevin Lee
@dr_kevinlee · X

Adrenal fatigue wrong diagnosis some practitioners use. There is concept of allostatic adaptation to chronic stress (e.g. modern lifestyle), many hormones can have different allostatic patterns - including cortisol- can have blunted pattern https://t.co/iBO1RtJHvp https://t.co/E5iKjTqbM8 https://t.co/zlPpsEht3G

Mar 14, 2022 · 5 likes · 5,446 followers View post →
Shaya Ang
@shaya_ang · X

https://t.co/r6SGp66CJQ

Feb 19, 2025 · 2 likes · 475 followers View post →
sofia
@sofiamendoncaa · X

Referências Bibliográficas: Sapolsky, R. M. (2004). Why Zebras Don’t Get Ulcers. New York: Henry Holt and Company. Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain. Physiological Reviews, 87(3), 873–904.

Sep 11, 2025 · 1 like · 9,560 followers View post →
O
@LimpOverShoot · X

@pitbullizjason @the_urb @NateFloof https://t.co/9NKA3OiXbT https://t.co/Rkcfa1rVW8 There ya lazy bastard. Next time learn to rely on yourself not “handouts from a stranger”

May 28, 2025 · 1 like · 5,776 followers View post →

All mentions

Impact of Chronic Stress on Brain Function and Health

Your brain is central to how we perceive and respond to stress. When stress becomes the norm, it triggers harmful changes that can lead to memory loss and emotional issues. This video examines cortisol's effect on the…

Psych2Go · Jul 12, 2025 199,575 views
sofia
@sofiamendoncaa · X

Referências Bibliográficas: Sapolsky, R. M. (2004). Why Zebras Don’t Get Ulcers. New York: Henry Holt and Company. Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain. Physiological Reviews, 87(3), 873–904.

Sep 11, 2025 · 1 like · 9,560 followers View post →
Melody Melton
@melton_melody · X

https://t.co/HhEIcKcxRl

Aug 13, 2025 · 168 followers View post →
eduarda
@plutonnica · X

Jul 23, 2025 · 1 like · 1,201 followers View post →
SH
@saakiharuno_ · X

RT @tiffymLuv: Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 14, 2025 · 5 shares · 393 followers View post →
Sarah♒✨
@0210Sarah · X

RT @tiffymLuv: Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 14, 2025 · 5 shares · 135 followers View post →
GaRu_09 |
@GaRu__09 · X

RT @tiffymLuv: Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 14, 2025 · 5 shares · 337 followers View post →
Yousra Dahbeche
@Dahbeche2Yousra · X

What Constant Stress Does To Your Brain https://t.co/Gq3O073pyT via @YouTube

Jul 14, 2025 · 6 followers View post →
Mafuyu ♦️ Vgen
@Mafuyuki_san · X

RT @tiffymLuv: Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 13, 2025 · 5 shares · 540 followers View post →
TiffymArt
@TiffymArt · X

RT @tiffymLuv: Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 13, 2025 · 5 shares · 9 followers View post →
tiffymLuv
@tiffymLuv · X

Had the opportunity to work on another Psych2go video:-)! This time I voiced it over as well >_<!

Jul 13, 2025 · 11 likes · 5 shares · 827 followers View post →
MED
@MedosDmed · X

Eh constantly numbing myself was a bad decision too https://t.co/CxAAbw62UL

Jul 13, 2025 · 2,929 followers View post →
Goabdes Bïárnu
@biarnu · X

VERY IMPORTANT VIDEO!!!!!!!!!!

Jul 12, 2025 · 95 followers View post →
CannibalCarWash
@CannibaCarWash · X

https://t.co/LbUUh1EEHf

Jul 12, 2025 · 1,176 followers View post →
sara.art
@saraart4 · X

neurobiology of stress and adaptation. Physiol Rev. → https://t.co/Nir8tV8zvt Effet du langage dissonant sur le stress chronique

Jul 10, 2025 · 8,462 followers View post →
Markku Hakali
@hakali91595 · X

How To Overcome TOXIC Shame https://t.co/NSVhiYJfsI via @YouTube

Jul 4, 2025 · 313 followers View post →
O
@LimpOverShoot · X

@pitbullizjason @the_urb @NateFloof https://t.co/9NKA3OiXbT https://t.co/Rkcfa1rVW8 There ya lazy bastard. Next time learn to rely on yourself not “handouts from a stranger”

May 28, 2025 · 1 like · 5,776 followers View post →
Mohamed Ibrahim
@Mohamed61722756 · X

https://t.co/8w97BDyAQD

May 7, 2025 · 21 followers View post →
Shaya Ang
@shaya_ang · X

https://t.co/r6SGp66CJQ

Feb 19, 2025 · 2 likes · 475 followers View post →
E. H. A.
@Marsutol · X

McEwen, B. S. (2007). Physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87(3), 873-904. doi: 10.1152/physrev.00041.2006

Aug 24, 2024 · 35 followers View post →
Dr Kevin Lee
@dr_kevinlee · X

Adrenal fatigue wrong diagnosis some practitioners use. There is concept of allostatic adaptation to chronic stress (e.g. modern lifestyle), many hormones can have different allostatic patterns - including cortisol- can have blunted pattern https://t.co/iBO1RtJHvp https://t.co/E5iKjTqbM8 https://t.co/zlPpsEht3G

Mar 14, 2022 · 5 likes · 5,446 followers View post →
Jim Bloom
@jimmyroybloom · X

https://t.co/8X7zsDs3z9

Sep 12, 2020 · 2,394 followers View post →
Nicholas Miraglia
@nickMira9 · X

RT @ToddHargrove: Related: “the brain … is the key organ of the stress response because it determines what is threatening and, therefore, s…

Jun 4, 2019 · 3 shares · 827 followers View post →
dpfaff
@PfaffSC · X

RT @ToddHargrove: Related: “the brain … is the key organ of the stress response because it determines what is threatening and, therefore, s…

Jun 3, 2019 · 3 shares · 14,162 followers View post →
scott white
@scottinnerfocus · X

RT @ToddHargrove: Related: “the brain … is the key organ of the stress response because it determines what is threatening and, therefore, s…

Jun 3, 2019 · 3 shares · 269 followers View post →
Todd Hargrove
@ToddHargrove · X

Related: “the brain … is the key organ of the stress response because it determines what is threatening and, therefore, stressful and also controls the behavioral and physiological responses to potentially stressful experiences.” — Bruce McEwen https://t.co/eLtZuLVlJ5

Jun 3, 2019 · 7 likes · 3 shares · 4,729 followers View post →