Nature November 2007 PMID 17972876

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system.

Jean Livet, Tamily A Weissman, Hyuno Kang, Ryan W Draft, Ju Lu, Robyn A Bennis, Joshua R Sanes, Jeff W Lichtman

Mentions

81
Peak: 8 in Jun 2020
across 5 sources since Mar 2020

Extended reach

145,312
potential audience

Total likes

132

Video views

5,013

Mentions per month

Mar 2020 – Mar 2025

Where it's discussed

  • Blogs33 articles
  • News26 articles
  • X / Twitter15 posts
  • Facebook5 posts
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AI synopsis

What people are saying

The collective discussions show strong interest and appreciation for the innovative visualization techniques, with posts describing the brainbow mouse as 'beautiful' and emphasizing how these methods advance understanding of neural circuits. The tone is excited and admiring, with some references to the foundational work of Lichtman and Sanes, highlighting the perceived importance and potential of these transgenic strategies.

AgreementModerate agreement

Most discussions warmly support the significance of the research, highlighting its potential to visualize neural networks and using positive language like 'love' and 'incredible.'

InterestHigh interest

The posts express high curiosity and appreciation, often mentioning the beauty and artistic aspect of fluorescence microscopy and neural visualization.

EngagementModerate engagement

Posts demonstrate active engagement by referencing specific techniques (like Brainbow) and sharing personal excitement or further resources, indicating they are invested in the topic.

ImpactModerate impact

While the posts reflect enthusiasm and recognition of the method's importance, they mostly praise the technology’s potential rather than debating or critiquing its broader implications.

Abstract in brief

  • The text discusses innovative genetic techniques, called Brainbow transgenes, that use Cre-lox recombination to produce multiple fluorescent protein colors in neurons, helping researchers visualize complex neural networks.
  • By integrating multiple Brainbow copies into transgenic mice, scientists can generate a wide variety of colors, enabling detailed mapping of neuron connections, such as reconstructing hundreds of axons and synapses in the cerebellum with about 90 different colors.
  • These methods also allow for tracking glial cells and neurons over time in live animals, making it easier to study how cells interact and organize in the nervous system, which could significantly advance understanding of neural circuitry.]

Top posts

Most liked on X and Bluesky
Türker KILIÇ
@turkerkilic · X

Referans: Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., … Lichtman, J. W. (2007). Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature, 450, 56. Retrieved from https://t.co/P2IPQXlIJK 3/3

Mar 5, 2020 · 33 likes · 2 shares · 113,981 followers View post →
Jessica Buck
@jessica_l_buck · X

Fluorescence microscopy images are my favourite kind of science as art. Microglial cells in the brain are always amazing, but the most incredible is the brainbow mouse! My images will never be anywhere near as beautiful

Sep 19, 2021 · 24 likes · 1 share · 610 followers View post →
Lady Nirvit
@Nirvit_tv · X

Nouvelle vidéo! Même après en avoir consacré un épisode entier, les méduses nous réservent encore de nombreuses surprises! et c'est en compagnie de Pierre le vadrouilleur que l'on va vous révéler les secret des méduses et de la GFP! https://t.co/oCoYgP9bJE https://t.co/ObQyAUFRPe

Jun 12, 2020 · 4 likes · 2 shares · 300 followers View post →
Devin Nunes' Cattle Dog
@Kaos_Vs_Control · X

@AmoneyResists I love me some transgenic mice (Brainbow; Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system) https://t.co/nngNeTchAP https://t.co/YryNtLvTcO

Mar 5, 2025 · 3 likes · 19,777 followers View post →
Pierre le Vadrouilleur
@PVadrouilleur · X

Rendez-vous sur la chaîne de @BioChronique pour découvrir notre collab' sur Méduse et les méduses, où mythologie et biologie se croisent ! ➡️ https://t.co/3eBEW0jmt5 https://t.co/HF1hVVPGeT

Jun 12, 2020 · 3 likes · 2 shares · 127 followers View post →
Lady Nirvit
@Nirvit_tv · X

D'ailleurs si vous ne l'avez pas encore vu c'est par ici

Jun 18, 2020 · 1 like · 300 followers View post →

All mentions

Devin Nunes' Cattle Dog
@Kaos_Vs_Control · X

@AmoneyResists I love me some transgenic mice (Brainbow; Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system) https://t.co/nngNeTchAP https://t.co/YryNtLvTcO

Mar 5, 2025 · 3 likes · 19,777 followers View post →
Miguel (Miggy) Chuapoco
@MiggyChuapoco · X

(Note: this isn't exactly identical to the original Brainbow method, but goal is similar: using 3 FPs to label many cells in the same sample. h/t the Lichtman and Sanes labs @Havard for their pioneering work developing Brainbow) https://t.co/hVgs0yL9BK https://t.co/rmIdZ5nVhz

Jan 14, 2022 · 85 followers View post →
Analio Dugarte
@analioj · X

RT @jessica_l_buck: Fluorescence microscopy images are my favourite kind of science as art. Microglial cells in the brain are always amazin…

Sep 19, 2021 · 1 share · 2,180 followers View post →
Jessica Buck
@jessica_l_buck · X

Fluorescence microscopy images are my favourite kind of science as art. Microglial cells in the brain are always amazing, but the most incredible is the brainbow mouse! My images will never be anywhere near as beautiful

Sep 19, 2021 · 24 likes · 1 share · 610 followers View post →
Fatih
@fatihaksu19 · X

RT @turkerkilic: Referans: Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., … Lichtman, J. W. (2007). Transgenic…

Jul 27, 2020 · 2 shares · 1,726 followers View post →
Lady Nirvit
@Nirvit_tv · X

@YTCreateurs Ma première collaboration pour avoir bien réussi a mélanger de la biologie et la mythologie ! https://t.co/vgqcDFovJy

Jul 2, 2020 · 300 followers View post →
Lady Nirvit
@Nirvit_tv · X

D'ailleurs si vous ne l'avez pas encore vu c'est par ici

Jun 18, 2020 · 1 like · 300 followers View post →
Fred et Emy
@FredetEmy1 · X

RT @PVadrouilleur: Rendez-vous sur la chaîne de @BioChronique pour découvrir notre collab' sur Méduse et les méduses, où mythologie et biol…

Jun 13, 2020 · 2 shares · 70 followers View post →
L'Explorataur
@ExplorataurYT · X

RT @BioChronique: Nouvelle vidéo! Même après en avoir consacré un épisode entier, les méduses nous réservent encore de nombreuses surprises…

Jun 12, 2020 · 2 shares · 24 followers View post →
Pierre le Vadrouilleur
@PVadrouilleur · X

Rendez-vous sur la chaîne de @BioChronique pour découvrir notre collab' sur Méduse et les méduses, où mythologie et biologie se croisent ! ➡️ https://t.co/3eBEW0jmt5 https://t.co/HF1hVVPGeT

Jun 12, 2020 · 3 likes · 2 shares · 127 followers View post →
Productions de MOA
@ProductionsMoa · X

La GFP et le secret des méduses (Bio-chronique 8 ft.pierre le vadrouilleur) https://t.co/L3sd9vNz7x via @YouTube

Jun 12, 2020 · 236 followers View post →
Zenixh
@Nem0_Zenixh · X

RT @BioChronique: Nouvelle vidéo! Même après en avoir consacré un épisode entier, les méduses nous réservent encore de nombreuses surprises…

Jun 12, 2020 · 2 shares · 550 followers View post →
Lady Nirvit
@Nirvit_tv · X

Nouvelle vidéo! Même après en avoir consacré un épisode entier, les méduses nous réservent encore de nombreuses surprises! et c'est en compagnie de Pierre le vadrouilleur que l'on va vous révéler les secret des méduses et de la GFP! https://t.co/oCoYgP9bJE https://t.co/ObQyAUFRPe

Jun 12, 2020 · 4 likes · 2 shares · 300 followers View post →
Türker KILIÇ
@turkerkilic · X

Referans: Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., … Lichtman, J. W. (2007). Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature, 450, 56. Retrieved from https://t.co/P2IPQXlIJK 3/3

Mar 5, 2020 · 33 likes · 2 shares · 113,981 followers View post →
Ordinary Person
@Ordinar65453293 · X

Referans: Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., … Lichtman, J. W. (2007). Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature, 450, 56. Retrieved from https://t.co/vRwJt9tR25 3/3

Mar 5, 2020 · 1 followers View post →