PubHawk
J Pain February 2008 PMID 18088561

Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions.

C Richard Chapman, Robert P Tuckett, Chan Woo Song

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Mentions

31
Peak: 18 in Nov 2019
across 2 sources since Nov 2019

Extended reach

97,559
potential audience

Total likes

102

Video views

125

Mentions per month

Nov 2019 – May 2025

Where it's discussed

  • X / Twitter29 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions frequently mention the article's significance, using words like 'good starting point' and 'awesome paper', which show enthusiasm and recognition of its importance. The tone suggests curiosity and acknowledgment of the article's contribution to understanding pain through interconnected systems, without delving deeply into specific scientific details.

AgreementModerate agreement

Most users express positive recognition or support for the article, describing it as a useful starting point or an 'awesome paper'.

InterestHigh interest

The discussions show high interest, with users engaging enthusiastically and highlighting the relevance of the systems approach to understanding pain.

EngagementModerate engagement

Engagement is moderate, with several users sharing full texts or recommending reading, indicating active but not extensive deep analysis.

ImpactModerate impact

The discussions reflect recognition of the article's potential influence, though primarily as a foundation for further exploration rather than immediate applied change.

Abstract in brief

  • The paper presents a systems approach to understanding pain, highlighting how injury triggers a complex, interconnected stress response involving nervous, endocrine, and immune systems that work together as a "supersystem."
  • Acute pain results from this supersystem's response to injury, while chronic pain may develop when this system becomes dysregulated, often influenced by social stressors, genetics, and personal history.
  • Recognizing the role of supersystem dysregulation can help clinicians better assess and treat chronic pain by considering the interdependent physiological processes affecting each individual uniquely.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Todd Hargrove
@ToddHargrove · X

Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions. https://t.co/8bJ98Cs0vJ https://t.co/4KmtMGsLWI

Nov 4, 2019 · 71 likes · 23 shares · 4,714 followers View post →
Arturo Goicoechea
@argoicoechea · X

Pain and Stress in a Systems Perspective Reciprocal Neural, Endocrine and Immune Interactions https://t.co/Vtb1WsI4vk

Apr 25, 2020 · 10 likes · 2 shares · 10,932 followers View post →
Arturo Goicoechea
@argoicoechea · X

Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. https://t.co/Vtb1WsI4vk

Jan 22, 2020 · 6 likes · 2 shares · 10,932 followers View post →
Dr. Demetry
@DrDemetry · X

@Irish_Physio @DerekGriffin86 Here’s some reading for you! https://t.co/JQyNBf8zZU https://t.co/3OlhRzgXm8

Oct 15, 2022 · 6 likes · 2 shares · 364 followers View post →
Dr. Demetry
@DrDemetry · X

@SeanGTGibbons @tomgoom @RogerKerry1 @gera_dev30 @BJSM_BMJ @lizbayleyphysio @AsafKlaf @Nic_Em_Andrews I find this article to be a good starting point: https://t.co/3OlhRyZmuA

Apr 15, 2022 · 1 like · 364 followers View post →
Derek Griffin
@DerekGriffin86 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 38,544 followers View post →

All mentions

Jonny Branney
@jonnybranney · X

RT @DrDemetry: @Irish_Physio @DerekGriffin86 Here’s some reading for you! https://t.co/JQyNBf8zZU https://t.co/3OlhRzgXm8

Oct 15, 2022 · 2 shares · 600 followers View post →
Kathy
@ketmpt · X

RT @DrDemetry: @Irish_Physio @DerekGriffin86 Here’s some reading for you! https://t.co/JQyNBf8zZU https://t.co/3OlhRzgXm8

Oct 15, 2022 · 2 shares · 713 followers View post →
Dr. Demetry
@DrDemetry · X

@Irish_Physio @DerekGriffin86 Here’s some reading for you! https://t.co/JQyNBf8zZU https://t.co/3OlhRzgXm8

Oct 15, 2022 · 6 likes · 2 shares · 364 followers View post →
Dr. Demetry
@DrDemetry · X

@SeanGTGibbons @tomgoom @RogerKerry1 @gera_dev30 @BJSM_BMJ @lizbayleyphysio @AsafKlaf @Nic_Em_Andrews I find this article to be a good starting point: https://t.co/3OlhRyZmuA

Apr 15, 2022 · 1 like · 364 followers View post →
JoaquimLamora
@JoaquimLamora · X

RT @argoicoechea: Pain and Stress in a Systems Perspective Reciprocal Neural, Endocrine and Immune Interactions https://t.co/Vtb1WsI4vk

Apr 25, 2020 · 2 shares · 1,129 followers View post →
Maite Goicoechea
@Goicomaite · X

RT @argoicoechea: Pain and Stress in a Systems Perspective Reciprocal Neural, Endocrine and Immune Interactions https://t.co/Vtb1WsI4vk

Apr 25, 2020 · 2 shares · 1,666 followers View post →
Arturo Goicoechea
@argoicoechea · X

Pain and Stress in a Systems Perspective Reciprocal Neural, Endocrine and Immune Interactions https://t.co/Vtb1WsI4vk

Apr 25, 2020 · 10 likes · 2 shares · 10,932 followers View post →
Liz Monserrath Ortiz
@LizMonserrath · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Apr 18, 2020 · 23 shares · 33 followers View post →
Apa
@AlpalBe · X

RT @argoicoechea: Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. https://t.co/Vtb1WsI4vk

Jan 22, 2020 · 2 shares · 850 followers View post →
Leonardo Rodríguez Lagos
@leo_rodriguezl · X

RT @argoicoechea: Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. https://t.co/Vtb1WsI4vk

Jan 22, 2020 · 2 shares · 196 followers View post →
Arturo Goicoechea
@argoicoechea · X

Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. https://t.co/Vtb1WsI4vk

Jan 22, 2020 · 6 likes · 2 shares · 10,932 followers View post →
Kirsty Forsythe
@kirstyfor · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 6, 2019 · 23 shares · 598 followers View post →
Paul Regan
@PaulRegan_ · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 6, 2019 · 23 shares · 268 followers View post →
Aaron Ngor
@aaron_the_AT · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 6, 2019 · 23 shares · 490 followers View post →
Shweta S, PT, MHS, CLT
@ShwetasPT · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 682 followers View post →
Juan Joost
@JuanJoost · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 133 followers View post →
Daniel Godeassi
@dangodeassi · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 203 followers View post →
Matt Brook O'Donnell
@mdbod · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 145 followers View post →
Tina
@LivingWellPain · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 2,638 followers View post →
Riccardo Gambugini
@riky_rich89 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 231 followers View post →
Joost van Wijchen
@jowi12 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 1,723 followers View post →
Adam Dobson
@adamdobson123 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 12,832 followers View post →
Scott McGill
@smcgill175 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 42 followers View post →
Diane Jacobs
@dfjpt · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 4,426 followers View post →
Derek Griffin
@DerekGriffin86 · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 38,544 followers View post →
Vagner Miolla
@vmiolla · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 171 followers View post →
John Ware PT, DHSc
@JohnWarePT · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 5, 2019 · 23 shares · 838 followers View post →
Mosiah Araújo Silva
@MosiahAraujo · X

RT @ToddHargrove: Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions…

Nov 4, 2019 · 23 shares · 68 followers View post →
Todd Hargrove
@ToddHargrove · X

Awesome paper (full text): Pain and Stress In a Systems Perspective: Reciprocal Neural, Endocrine and Immune Interactions. https://t.co/8bJ98Cs0vJ https://t.co/4KmtMGsLWI

Nov 4, 2019 · 71 likes · 23 shares · 4,714 followers View post →