J Clin Endocrinol Metab May 2008 PMID 18198223

Acyl and total ghrelin are suppressed strongly by ingested proteins, weakly by lipids, and biphasically by carbohydrates.

Karen E Foster-Schubert, Joost Overduin, Catherine E Prudom, Jianhua Liu, Holly S Callahan, Bruce D Gaylinn, Michael O Thorner, David E Cummings

Mentions

26
Peak: 9 in Mar 2019
across 2 sources since Mar 2019

Extended reach

402,069
potential audience

Total likes

5,147

Video views

130,688

Mentions per month

Mar 2019 – Mar 2025

Where it's discussed

  • X / Twitter24 posts
  • YouTube2 videos

AI synopsis

What people are saying

The digital discussions demonstrate a high level of agreement and curiosity about the study's findings, with posts highlighting that proteins suppress hunger hormones most effectively, such as in the statement 'Ghrelin is suppressed most by protein, weakly by fat, & biphasically by carbs.' The tone is informational and analytical, using phrases like 'fun fact' and emphasizing the physiological mechanisms, which reflect genuine interest and impact of the research.

AgreementStrong agreement

Most discussions acknowledge and support the findings of the study, emphasizing the differential effects of macronutrients on ghrelin suppression.

InterestHigh interest

The posts are highly focused on the topic of hunger hormones and diet strategies, showing strong engagement with the subject matter.

EngagementModerate engagement

Several comments analyze the mechanisms behind ghrelin suppression and discuss implications for diet and health, indicating moderate to deep engagement.

ImpactModerate impact

The discussions reflect awareness of how these findings could influence dietary choices and weight management strategies, though they are mostly exploratory.

Abstract in brief

  • Ingested proteins strongly suppress ghrelin levels, lipids less effectively, and carbohydrates cause a biphasic suppression, meaning ghrelin levels first decrease then rebound after meals.
  • The study found that proteins lead to the greatest reduction in both acyl and total ghrelin levels, followed by carbohydrates, then lipids, which have the least suppressive effect.
  • These results support the idea that high-protein, low-carb diets may help promote weight loss by more effectively reducing hunger hormones like ghrelin, while high-fat diets may be less effective in this regard.]

Top posts

Most liked on X and Bluesky
Michael Mindrum, MD
@MichaelMindrum · X

Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin is suppressed the most by protein, weakly by fat, & biphasically by carbs (study 2008). @tednaiman @eatlikeanimals https://t.co/VlGGnb3We6 https://t.co/WuDyUjItqX

Nov 1, 2021 · 50 likes · 8 shares · 10,095 followers View post →
Ian Lind, MS CN
@Healthspan_Diet · X

“Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carbs led to a rebound in ghrelin. https://t.co/zqb2yePi6r @raphaels7 @tednaiman @Nutradvance @DiscoStew66 @whsource @ChrisMasterjohn @TuckerGoodrich @puddleg

Mar 7, 2019 · 30 likes · 8 shares · 528 followers View post →
Naoki @ live in Japan
@1dokiri_ · X

【タンパク質には食欲抑制効果がある】 タンパク質には、食欲増進ホルモン『グレリン』の分泌を抑える効果があります。 日中にどうしてもお腹が空いてしまったときには、飲み物にプロテインを溶かすのもオススメです

Mar 20, 2024 · 11 likes · 427 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Fun fact: fat suppresses ghrelin (hunger hormone) less than protein or carbs. Carbs suppress it most but then can cause rebound higher levels, whilst protein causes prolonged suppression https://t.co/cKX9PTvvHN Ofc this gets even more complicated irl as we eat food not nutrients

Mar 9, 2023 · 4 likes · 3 shares · 8,809 followers View post →
Kirsty Woods
@MetabolicEP · X

"But all calories are created equal" Original source: https://t.co/u0hz1S0Lmv https://t.co/fMXRq3MLiS

Sep 2, 2020 · 1 like · 2,041 followers View post →
Tim Noakes
@ProfTimNoakes · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 7, 2019 · 8 shares · 157,824 followers View post →

All mentions

Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: fat suppresses ghrelin (hunger hormone) less than protein or carbs. Carbs suppress it most but then can cause…

Mar 9, 2025 · 3 shares · 8,809 followers View post →
Naoki @ live in Japan
@1dokiri_ · X

【タンパク質には食欲抑制効果がある】 タンパク質には、食欲増進ホルモン『グレリン』の分泌を抑える効果があります。 日中にどうしてもお腹が空いてしまったときには、飲み物にプロテインを溶かすのもオススメです

Mar 20, 2024 · 11 likes · 427 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

RT @angryhacademic: Fun fact: fat suppresses ghrelin (hunger hormone) less than protein or carbs. Carbs suppress it most but then can cause…

Mar 9, 2024 · 3 shares · 8,809 followers View post →
smurfsj
@smurfsj · X

RT @angryhacademic: Fun fact: fat suppresses ghrelin (hunger hormone) less than protein or carbs. Carbs suppress it most but then can cause…

Mar 9, 2023 · 3 shares · 132 followers View post →
Harriet Carroll: Long Covid Scientific Consultancy
@angryhacademic · X

Fun fact: fat suppresses ghrelin (hunger hormone) less than protein or carbs. Carbs suppress it most but then can cause rebound higher levels, whilst protein causes prolonged suppression https://t.co/cKX9PTvvHN Ofc this gets even more complicated irl as we eat food not nutrients

Mar 9, 2023 · 4 likes · 3 shares · 8,809 followers View post →
Andrew
@Andrew__Lima · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 2, 2021 · 8 shares · 7 followers View post →
alexander ruhle
@alexruhle · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 2, 2021 · 8 shares · 171 followers View post →
Dupont Daniel
@DupontDaniel2 · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 2, 2021 · 8 shares · 23 followers View post →
Max Andrade
@psycheparaiba · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 1, 2021 · 8 shares · 203 followers View post →
Loyd Christensen
@loiteringloyd · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 1, 2021 · 8 shares · 159 followers View post →
Carl Rivir
@CarlRivir · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 1, 2021 · 8 shares · 183 followers View post →
Valerie, RD, MPH
@RDValerie · X

RT @MichaelMindrum: Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin…

Nov 1, 2021 · 8 shares · 33,952 followers View post →
Michael Mindrum, MD
@MichaelMindrum · X

Study break. Ghrelin, the major hunger (orixogenic) hormone increases before meals and decreases after meals. Ghrelin is suppressed the most by protein, weakly by fat, & biphasically by carbs (study 2008). @tednaiman @eatlikeanimals https://t.co/VlGGnb3We6 https://t.co/WuDyUjItqX

Nov 1, 2021 · 50 likes · 8 shares · 10,095 followers View post →
Kirsty Woods
@MetabolicEP · X

"But all calories are created equal" Original source: https://t.co/u0hz1S0Lmv https://t.co/fMXRq3MLiS

Sep 2, 2020 · 1 like · 2,041 followers View post →
Gabor Erdosi
@gerdosi · X

@MathieuBoucha15 And of course, the ultimate blow is not the poor lonely ghrelin, but when it meets quickly dropping BG levels. As it happens after consuming heavily refined carbs. 1. https://t.co/DkmE7uj7Aw 2. https://t.co/4WZJh7aUwB

Aug 11, 2019 · 25,867 followers View post →
laili
@laili_lai · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 8, 2019 · 8 shares · 69 followers View post →
Vet Goed
@VetGoed · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 8, 2019 · 8 shares · 386 followers View post →
Michael Joseph
@Nutradvance · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 8, 2019 · 8 shares · 11,767 followers View post →
Dr. William Araujo
@drwilliamaraujo · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 8, 2019 · 8 shares · 342 followers View post →
Laura Bradley
@L4M51236 · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 7, 2019 · 8 shares · 81 followers View post →
Messner
@_messner · X

Acyl and Total Ghrelin Are Suppressed Strongly by Ingested Proteins, Weakly by Lipids, and Biphasically by Carbohydrates https://t.co/lC32KwfRqR

Mar 7, 2019 · 59 followers View post →
Ana Cláudia
@Anawsantos · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 7, 2019 · 8 shares · 359 followers View post →
Tim Noakes
@ProfTimNoakes · X

RT @Healthspan_Diet: “Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carb…

Mar 7, 2019 · 8 shares · 157,824 followers View post →
Ian Lind, MS CN
@Healthspan_Diet · X

“Hunger hormone” Ghrelin is suppressed most by #protein, “biphasically” by #carbs, and least by #fat. After 3 hr, carbs led to a rebound in ghrelin. https://t.co/zqb2yePi6r @raphaels7 @tednaiman @Nutradvance @DiscoStew66 @whsource @ChrisMasterjohn @TuckerGoodrich @puddleg

Mar 7, 2019 · 30 likes · 8 shares · 528 followers View post →