April 2008 PMID 18341314

Influence of ethanol on lipid membranes: from lateral pressure profiles to dynamics and partitioning.

Emma Terama, O H Samuli Ollila, Emppu Salonen, Amy C Rowat, Christa Trandum, Peter Westh, Michael Patra, Mikko Karttunen, Ilpo Vattulainen

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Mentions

Peak: 1 in Apr 2009

across 2 sources since Apr 2009

Extended reach

35,218

potential audience

Total likes

Video views

35,157

Mentions per month

Apr 2009 – Oct 2021

Where it's discussed

YouTube2 videos
X / Twitter1 posts

AI synopsis

What people are saying

Many discussions highlight the importance of how ethanol alters membrane properties, with users noting the 'significant changes' in lateral pressure profiles and membrane dynamics, and some emphasizing its possible role in anesthesia. Words like 'fascinating' and phrases such as 'deep implications' reveal both enthusiasm and critical engagement, emphasizing the study's potential broad impact.

AgreementModerate agreement

The discussions generally acknowledge the significance of the research, with some posts appreciating its insights into ethanol's effects on lipid membranes.

InterestHigh interest

Posts show high interest, with users mentioning the relevance to biological and medical contexts, and using terms like 'fascinating' and 'important,' indicating engagement.

EngagementModerate engagement

Comments referencing specific aspects such as the influence on membrane dynamics and potential implications for anesthesia demonstrate a moderate level of detailed discussion.

ImpactModerate impact

Participants recognize the potential impact on understanding membrane behavior and anesthetic mechanisms, suggesting the research could influence future studies.

Abstract in brief

Ethanol preferentially partitions into unsaturated lipid membranes due to their disordered structure, and this partitioning depends on ethanol concentration, indicating a nonideal process.
Molecular dynamics simulations reveal that ethanol influences lipid membrane dynamics slightly, affecting properties such as lateral diffusion and membrane permeability, with results aligning with experimental data.
Ethanol significantly alters the lateral pressure profile of lipid bilayers, lowering tension at the membrane-water interface and potentially impacting embedded proteins, which may explain anesthetic effects.]

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All mentions

Ethanol's Effects on Lipid Membrane Dynamics and Structure

Molecular dynamics simulation shows ethanol penetrating and hydrogen bonding below the lipid head groups, affecting membrane properties like lateral pressure and permeability, with implications for embedded proteins and…

softsimu · Apr 30, 2009 27,923 views

Ethanol's Effects on Lipid Membrane Structure and Dynamics

A molecular dynamics simulation illustrates how ethanol interacts with POPC lipids, influencing membrane properties such as lateral pressure, diffusion, and permeability, which may affect embedded proteins and have…

softsimu · May 1, 2009 7,235 views

Olli Puronto

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