May 2008 PMID 18416885

24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.

Kristine L Clark, Wayne Sebastianelli, Klaus R Flechsenhar, Douglas F Aukermann, Felix Meza, Roberta L Millard, John R Deitch, Paul S Sherbondy, Ann Albert

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Mentions

187
Peak: 5 in Sep 2020
across 6 sources since Nov 2018

Extended reach

792,159
potential audience

Total likes

2,662

Video views

127,203

Mentions per month

Nov 2018 – Dec 2025

Where it's discussed

  • News101 articles
  • X / Twitter42 posts
  • Facebook29 posts
  • YouTube7 videos
  • Blogs6 articles
  • Reddit2 posts

AI synopsis

What people are saying

The discussions demonstrate a generally positive reception to the study, with phrases like "good evidence" and "study shows" indicating support and interest in collagen’s benefits. Examples include users sharing personal supplement routines, referencing other research, and questioning the study's robustness, which reveals a mix of curiosity and cautious optimism. The tone ranges from confident to skeptical, showing engagement but also critical evaluation of the evidence.

AgreementModerate agreement

Most discussions acknowledge the study's findings that collagen may benefit joint pain and support its potential efficacy based on existing research.

InterestHigh interest

Posts show high curiosity, with participants seeking to verify results and sharing personal experiences with collagen supplements.

EngagementHigh engagement

Many users delve into detailed comments, referencing additional studies, discussing supplement doses, or debating the validity of findings.

ImpactModerate impact

The discussions reflect a moderate influence, with some users considering adopting collagen supplements, though skepticism remains due to limited data.

Abstract in brief

  • The 24-week study investigated the effects of collagen hydrolysate (a supplement thought to support cartilage health) on joint pain, mobility, and inflammation in active athletes without joint disease.
  • Participants were randomly assigned to receive either collagen hydrolysate or a placebo, and their joint pain levels were measured using visual analogue scales during the study.
  • Results showed that athletes taking collagen hydrolysate experienced significant reductions in joint pain during activities like walking, standing, and at rest, indicating the supplement's potential to alleviate activity-related joint discomfort.

Top posts

Most liked on X and Bluesky
JT | Jerry Teixeira
@jerryteixeira · X

Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial to connective tissues and can help alleviate join pain https://t.co/hFgYaSWFwn

Sep 25, 2020 · 32 likes · 4 shares · 79,007 followers View post →
ricardo
@ricardoricacio · X

@DrMauricioGon https://t.co/mPXD7Jnqy4 yo lo he usado. Hay estudios que demuestran si funciona

Mar 7, 2023 · 15 likes · 617 followers View post →
Julianne Taylor, Nutritionist
@juliannejtaylor · X

@SailorLapin @langernutrition Yes it helps https://t.co/hgkvmzg9Zx

Dec 15, 2020 · 9 likes · 5,315 followers View post →
KENTO/カジュアルに栄養の本質を学べる学校を作る。
@sudokeeen · X

参考 https://t.co/q5qZo2MGfH

Sep 24, 2025 · 6 likes · 51,990 followers View post →
Analyze & Optimize
@Outdoctrination · X

@astro_toaster @TuckerGoodrich https://t.co/DTcMIbRMWK

Apr 22, 2024 · 4 likes · 115,293 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

@nashi506 サイキックでもなんでもないです 関節痛についてのコラーゲンの改善効果は論文あり https://t.co/kGWkghpfiL 爪に対する改善効果も論文あり https://t.co/lHSQmtiaS1

Nov 5, 2022 · 2 likes · 125,514 followers View post →

All mentions

KENTO/カジュアルに栄養の本質を学べる学校を作る。
@sudokeeen · X

参考 https://t.co/q5qZo2MGfH

Sep 24, 2025 · 6 likes · 51,990 followers View post →
Carlos Mendoza
@carlosatal · X

@MariaCruzad ¡Gracias por compartir tu experiencia! No es placebo: estudios en condromalacia, artrosis y dolor articular han mostrado mejoría clínica y funcional con colágeno hidrolizado. ▶️ https://t.co/pz4aMGZb6Z ▶️ https://t.co/zz5Tjap2AT #ColágenoFunciona

Jun 23, 2025 · 383 followers View post →
Crunchy
@Crunch_a_rama · X

@UnwokeMediaInc @LeddyLLC Here's an actual study with real data showing that collagen supplements can have a beneficial effect: https://t.co/kqrmWDHlgc

Jun 6, 2025 · 134 followers View post →
William Lagakos
@caloriesproper2 · X

Getting old and I exercise a lot. Some evidence says collagen may be helpful https://t.co/1hRO6rQyRm

Nov 12, 2024 · 2,703 followers View post →
joaco luza
@joacoluza · X

@cingolani_oscar Acá ya tenes un estudio que dice que funciona me tomo 2 minutos encontrarlo https://t.co/9BJVSMWRx6

Oct 23, 2024 · 9 followers View post →
Douglas Kalman PhD
@dougkalmanphdrd · X

A #PennState #throwback study on #Collagen for joint health. "Despite the study's size & limitations, the results suggest that athletes consuming collagen hydrolysate can reduce parameters (such as pain) that have a negative impact on athletic performance" https://t.co/LD3BuGuRcX

May 21, 2024 · 2 likes · 5,450 followers View post →
Dr Roy Bartel-Taverner
@TavernerRoy · X

Good evidence building for collagen - higher proportion of glycine (most basic amino acid) which is common in ligaments and skin etc so helps with joint pain and skin elasticity. I now take 15-30g mixed with vitamin C ontop of my normal whey protein. E.g. https://t.co/aAV1I7VTdc

May 14, 2024 · 16 followers View post →
Analyze & Optimize
@Outdoctrination · X

@astro_toaster @TuckerGoodrich https://t.co/DTcMIbRMWK

Apr 22, 2024 · 4 likes · 115,293 followers View post →
Langostarenacido
@LangostaReborn · X

@DrChavezDiaz Tu critica igual que tu criterio; todo pendejo ¿quien dijo que el caldo de huesos sirve para los huesos? El caldo de huesos es sabroso, solo eso. Para las articulaciones https://t.co/KlihWaqSxr

Apr 21, 2024 · 249 followers View post →
Iker.
@ikervk · X

Y nos querían engañar diciendo que el colágeno no funciona... https://t.co/gGdf5FMHqz

Dec 1, 2023 · 1 like · 259 followers View post →
Corey
@CoreyBaldwin18 · X

RT @BowTiedVitamins: @jamiehandsome6 https://t.co/7YlUkBBkdR https://t.co/OvNH6LZltp https://t.co/xQjiMgg81f

Oct 18, 2023 · 1 share · 143 followers View post →
Vitamin King | Stacks Vitamin Company
@BowTiedVitamins · X

@jamiehandsome6 https://t.co/7YlUkBBkdR https://t.co/OvNH6LZltp https://t.co/xQjiMgg81f

Oct 18, 2023 · 1 share · 45,829 followers View post →
Vitamin King | Stacks Vitamin Company
@KingOfVitamins · X

@jamiehandsome6 https://t.co/7YlUkBBkdR https://t.co/OvNH6LZltp https://t.co/xQjiMgg81f

Oct 18, 2023 · 1 share · 47,738 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/wi14wR6KrU Estudio de 24 semanas sobre el uso de hidrolizado de colágeno como suplemento dietético en atletas con dolor articular relacionado con la actividad física

Sep 13, 2023 · 8,041 followers View post →
TheFrenchEpidemiologist
@frenchepidemio · X

Si on s'intéresse à une des plus grosses études inclues dans la review, un essai randomisé contrôlé en double aveugle qui teste 10g de collagène hydrolysé vs du xanthane en placebo chez des sportifs (on se dit chouette design au départ...) https://t.co/JJ9mNCveSh

Sep 6, 2023 · 1 like · 15,172 followers View post →
galaxysplain
@galaxysplain · X

@ScepticalDoctor 10 grams of collagen hydrolysate + liquid vs xanthan +liquid: https://t.co/C5ba3KdTfB 5 grams of "bioactive collagen peptides" vs maltodextrin: https://t.co/VIDgw0T8tY 2.5 grams of high-glycine "specific collagen peptites" vs maltodextrin: https://t.co/7fpgHEDPnA

May 3, 2023 · 490 followers View post →
ricardo
@ricardoricacio · X

@DrMauricioGon https://t.co/mPXD7Jnqy4 yo lo he usado. Hay estudios que demuestran si funciona

Mar 7, 2023 · 15 likes · 617 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

@nashi506 サイキックでもなんでもないです 関節痛についてのコラーゲンの改善効果は論文あり https://t.co/kGWkghpfiL 爪に対する改善効果も論文あり https://t.co/lHSQmtiaS1

Nov 5, 2022 · 2 likes · 125,514 followers View post →
ACycloneDoc
@CyEngineerDOc · X

@LearnUSAhistory Yep! "24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain - PubMed" https://t.co/rOr5gCKnYj

Jul 20, 2022 · 1,171 followers View post →
アベケン
@abekenblog · X

昔、まだ知識が無い時に「コラーゲンとかは摂取しても消化の際にアミノ酸に分解されちゃうから関節痛とかに効果ない」って何かで見た記憶があるんだけどそんなことないって研究もあるんだね。関節痛ある場合はサプリからのアプローチもアリなのかも。 https://t.co/4j0PKsFiwM

Jul 7, 2022 · 1 like · 476 followers View post →
Healthful Papa
@healthfulpapa · X

Love #running ? You probably need some collagen. Study shows complete collagen can help with joint pain https://t.co/V610MXCwtV

Jun 2, 2022 · 29 followers View post →
Healthful Papa
@healthfulpapa · X

Study shows collagen is probably the best thing for joint health. https://t.co/V610MXCwtV #jointpain #arthritis #skincare

Jun 2, 2022 · 29 followers View post →
Pharmalab24
@Pharmalab2413 · X

COLLAGENE usi e caratteristiche https://t.co/8l9UjbbgVn

Feb 27, 2022 · 3 followers View post →
Alwyn Cosgrove
@alwyncosgrove · X

@Cernovich Yep. https://t.co/GUU5d2EQ5Z Seems enhanced results with high dose vitamin C supplementation at the same time

Sep 26, 2021 · 1 like · 17,061 followers View post →
Kristie Leong M.D.
@DrKristieLeong · X

@debjshaw @Drstevenhobbs You could take a collagen supplement. Some evidence to support the benefits. https://t.co/bmOiloBGqo

Sep 21, 2021 · 2 likes · 59,514 followers View post →
Oksana Andreiuk, MBiotech
@CDNBiohacker · X

https://t.co/Wg2djGdssm

Aug 24, 2021 · 602 followers View post →
Bader alshatti Ms
@alshatti_fit · X

@Ay_Maaa اذا لديك اصابة او نقص :نعم يحسن وظائف المصابين بهشاشة العظام https://t.co/RPC7UdEZz4 https://t.co/vLCopK2tTn يحسن من الالام الركبة https://t.co/xPNe9P5C2L ومن نطاقها https://t.co/a6SLqswFS5

Aug 5, 2021 · 9,913 followers View post →
laili
@laili_lai · X

RT @jerryteixeira: Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial…

Apr 13, 2021 · 4 shares · 66 followers View post →
Colin Erdman
@ColinErdman · X

@John_Papa I hear that. I take about 6g of hydrolyzed collagen (Costco) every morning, and that definitely seems to help [study linked]. https://t.co/TpGaDvzQJx

Mar 23, 2021 · 143 followers View post →
Suaminya Bu Amalia
@wix95 · X

@oaclown @raniha27 @lintangnovem https://t.co/cAbROhRA9Z "Collagen hydrolysate to support joint health and possibly reduce the risk of joint deterioration"

Jan 27, 2021 · 1 like · 516 followers View post →
Julianne Taylor, Nutritionist
@juliannejtaylor · X

@SailorLapin @langernutrition Yes it helps https://t.co/hgkvmzg9Zx

Dec 15, 2020 · 9 likes · 5,315 followers View post →
Orson
@Orsonkartt · X

RT @jerryteixeira: Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial…

Sep 25, 2020 · 4 shares · 1,027 followers View post →
BlueSamuraiZero
@BlueSamuraiZero · X

RT @jerryteixeira: Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial…

Sep 25, 2020 · 4 shares · 1,014 followers View post →
B A H B
@23oowj · X

RT @jerryteixeira: Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial…

Sep 25, 2020 · 4 shares · 365 followers View post →
JT | Jerry Teixeira
@jerryteixeira · X

Collagen protein is not adequate for muscle protein synthesis/recovery But many studies suggest that it is beneficial to connective tissues and can help alleviate join pain https://t.co/hFgYaSWFwn

Sep 25, 2020 · 32 likes · 4 shares · 79,007 followers View post →
Kristie Leong M.D.
@DrKristieLeong · X

@Natasha_Irina_ I think there is some evidence that it improves joint health: https://t.co/bmOiloThOY and, possibly, skin aging: https://t.co/dkWbLqMqKn I don't think it's a miracle pill, but there are studies showing modest benefits.

Sep 24, 2020 · 59,514 followers View post →
Joel Prowting, PhD(c), CSCS
@JoelProwting · X

@mackinprof @APNMjournal Thanks for sharing! Seems to be in direct contrast to this study: https://t.co/CN64VfPYwi I'm glad data are beginning to accumulate (and similar studies being ran by different lab groups!) regarding CP. Very unclear if there's meaningful benefits currently

Jul 3, 2020 · 160 followers View post →
Mitch Challinor
@ChallinorNutri_ · X

https://t.co/q1Zo9klqFG

Jan 15, 2020 · 2 followers View post →
Catherine Collins
@RD_Catherine · X

@alasdairalas The research limited and flawed- confounders make studies less robust. eg this study: https://t.co/2O6IILRJvO collagen suppl group had higher dietary protein contribution and greater use of other therapies. Subjective evaluation of symptoms don't nec relate to collagen synthesis

Jan 6, 2020 · 1 like · 7,773 followers View post →
MarkCroucher2
@MarkCroucher2 · X

Despite the study's size and limitations, the results suggest that athletes consuming collagen hydrolysate can reduce parameters (such as pain) that have a negative impact on athletic performance. https://t.co/GJle7Xa96y

Nov 22, 2019 · 1 like · 636 followers View post →
David McConnell
@D4vidMcConnell · X

@BootstrapCook https://t.co/Bh3hQeggfi

Oct 4, 2019 · 452 followers View post →
Milkkieway☁️
@Milkkieway_1996 · X

https://t.co/KOoSDy46ge

Jun 13, 2019 · 95 followers View post →