@BelindaFettke @FructoseNo @USDA @HHSGov @HouseAgDems @HouseAgGOP @SenateAgGOP @SenateAg @DrAseemMalhotra @DrPaulMason @FatEmperor @MaryanneDemasi @VinnieTortorich Belinda, let me add something here if you don't mind, "Wheat is not food"! Nothing that is highly addictive and causes gut permeability should be considered as food. THX. https://t.co/57JXyJeWKB https://t.co/lvc2iZvZJI https://t.co/JBcJXm476B #gliadin #zonulin https://t.co/OG6ATpYsRk
Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3.
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Sep 2019 – Sep 2025Where it's discussed
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Facebook9 posts
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X / Twitter7 posts
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Blogs6 articles
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YouTube3 videos
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Reddit2 posts
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News2 articles
AI synopsis
What people are saying
The overall digital discussions show mixed reactions, with one user dismissing wheat as 'not food' and implying harmful effects, exemplified by words like 'highly addictive,' while others simply comment on the findings, using phrases like 'Wheat is not food' to highlight concerns. The tone varies from skeptical to inquisitive, reflecting curiosity but limited deep engagement with the science or its broader implications.
Most discussions show neutral or mixed responses, with some users skeptical or dismissive about the health implications, reflecting a balanced or uncertain stance.
The interest level is moderate, with some users sharing opinions or asking questions, but many posts largely reiterate the article's findings without deep analysis.
Posts reflect personal reactions, comments on wheat's role, and brief mentions of related health issues, indicating some engagement but not deep scientific debate.
The discussions suggest awareness but do not demonstrate widespread or profound influence on opinions or practices, indicating a moderate perceived impact.
Abstract in brief
- Gliadin, a component of gluten, interacts with the chemokine receptor CXCR3 on intestinal cells, which increases intestinal permeability and triggers zonulin release, an early event in celiac disease development.
- Experiments showed that gliadin binds directly to CXCR3, involving specific peptides, and this interaction activates a pathway involving MyD88, leading to increased zonulin and permeability; this effect is absent in mice lacking CXCR3.
- In people with active celiac disease, the receptor CXCR3 is elevated, but its levels normalize with a gluten-free diet, indicating its role in disease progression and the importance of gliadin-CXCR3 interaction in intestinal barrier impairment.]
Top posts
Most liked on X and Bluesky@siobhan_huggins @MaoZhou https://t.co/ZDFxLAQKNq "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
@Tu_Quoque_4_U @CarnivoreAugust @UnModded_Human https://t.co/hv4FojtQbw "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
RT @Sadrien_GW2: @siobhan_huggins @MaoZhou https://t.co/ZDFxLAQKNq "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Rele…
@DrCraigH https://t.co/T9RBjc5Hwq … "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3 https://t.co/sx4ZNQjjta
All mentions
Understanding the Impact of Gluten Component Gliadin on Intestinal Permeability
This video explores how gliadin, a gluten component, interacts with CXCR3 receptors in the gut, increasing permeability and triggering zonulin release. It highlights the connection to celiac disease and the effects of a…
Understanding Gluten's Impact on Intestinal Health and Disease Risk
Gluten, mainly in wheat, rye, and barley, is linked to increased intestinal permeability, dysbiosis, and inflammation, which may lead to autoimmune or chronic inflammatory diseases. This video explains the mechanisms…
Gliadin's Role in Increasing Intestinal Permeability and Celiac Disease
Gliadin, a gluten component, binds to the chemokine receptor CXCR3 on intestinal cells, increasing permeability and triggering zonulin release. This process plays a key role in celiac disease development and can be…
@Tu_Quoque_4_U @CarnivoreAugust @UnModded_Human https://t.co/hv4FojtQbw "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
@BelindaFettke @FructoseNo @USDA @HHSGov @HouseAgDems @HouseAgGOP @SenateAgGOP @SenateAg @DrAseemMalhotra @DrPaulMason @FatEmperor @MaryanneDemasi @VinnieTortorich Belinda, let me add something here if you don't mind, "Wheat is not food"! Nothing that is highly addictive and causes gut permeability should be considered as food. THX. https://t.co/57JXyJeWKB https://t.co/lvc2iZvZJI https://t.co/JBcJXm476B #gliadin #zonulin https://t.co/OG6ATpYsRk
"Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3" https://t.co/PJvmfsicyl
Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3 https://t.co/sx4ZNQjjta
@DrCraigH https://t.co/T9RBjc5Hwq … "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
RT @Sadrien_GW2: @siobhan_huggins @MaoZhou https://t.co/ZDFxLAQKNq "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Rele…
@siobhan_huggins @MaoZhou https://t.co/ZDFxLAQKNq "Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3"
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