Am J Physiol Heart Circ Physiol October 2008 PMID 18660448

Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis.

Fina Lovren, Yi Pan, Adrian Quan, Hwee Teoh, Guilin Wang, Praphulla C Shukla, Kevin S Levitt, Gavin Y Oudit, Mohammed Al-Omran, Duncan J Stewart, Arthur S Slutsky, Mark D Peterson, Peter H Backx, Josef M Penninger, Subodh Verma

Mentions

94
Peak: 46 in May 2020
across 4 sources since Apr 2020

Extended reach

3,452,025
potential audience

Total likes

33,132

Video views

3,431,972

Mentions per month

Apr 2020 – Nov 2021

Where it's discussed

  • YouTube68 videos
  • X / Twitter23 posts
  • Facebook2 posts
  • News1 articles

AI synopsis

What people are saying

The overall discussions emphasize the role of ACE2 in protecting blood vessels, as seen in posts referencing its potential for cardiovascular therapies, while others discuss its relevance to COVID-19's impact on endothelium, using words like 'significant' and 'game changer' which highlight perceived high impact and interest. The tone varies from supportive acknowledgment to cautious concern about COVID-19 effects.

AgreementModerate agreement

Most discussions acknowledge the significance of ACE2 in vascular protection and its potential therapeutic implications, showing a general consensus of support.

InterestModerate interest

Posts express moderate interest, with some highlighting the relevance to diseases like COVID-19 and cardiovascular health, but few delve deeply into technical details.

EngagementNeutral engagement

There is some engagement, especially with mentions of research support and potential clinical impacts, but limited in-depth analysis.

ImpactModerate impact

Discussions touch on the importance of ACE2 in health and disease, suggesting a recognition of its high potential impact, especially in contexts like COVID-19 and atherosclerosis.

Abstract in brief

  • ACE2 helps protect blood vessels and reduce atherosclerosis by balancing the effects of ANG II, which can cause endothelial dysfunction.
  • Increasing ACE2 activity improves endothelial cell functions like migration and blood vessel formation, while reducing inflammatory responses and oxidative stress linked to reactive oxygen species.
  • The study suggests that therapies targeting ACE2 could be a new way to prevent vascular problems and the development of atherosclerosis.

Top posts

Most liked on X and Bluesky
Jeff Segor
@JSegor · X

COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 27, 2020 · 2 likes · 2 shares · 753 followers View post →
Tom Poole
@TomPoole007 · X

#oxidativestress https://t.co/snpGVmMQYC #Ace2 #ace2receptor #a779 #ros #angiotensin #SARSCoV2 #hadph #diabetes #obesity #angiotensin17 #endothelium

Apr 29, 2020 · 1 like · 1,780 followers View post →
cydiddy
@cyofallcy · X

@Parsifaler Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis https://t.co/njahNHTngD

Nov 13, 2021 · 1 like · 453 followers View post →
#FBPE #Brexit is a coup #Independence4OurNations
@EUnotCoup · X

RT @JSegor: COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 28, 2020 · 2 shares · 6,695 followers View post →
Democracy, Love, Peace, ClimateEmergncy, FBPPR
@KatharineJStin2 · X

RT @JSegor: COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 28, 2020 · 2 shares · 2,905 followers View post →
Graham Dellaire @docdellaire.bsky.social
@DocDellaire · X

@akelvinlab Pretty relevant paper here in thinking about COVID19 and your cardiovascular health... ACE2 and atherosclerosis. https://t.co/138g8faALD

May 5, 2020 · 2,664 followers View post →

All mentions

cydiddy
@cyofallcy · X

@Parsifaler Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis https://t.co/njahNHTngD

Nov 13, 2021 · 1 like · 453 followers View post →
dilated chakra
@TobbinIsrael · X

@CoachHylland @BobCjones2nd @latsondheimer https://t.co/H263OXVSEh

Jul 4, 2020 · 166 followers View post →
Md Mosaraf Hossain
@MdMosar30515459 · X

Online press briefing 12 May 2020 করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস... https://t.co/5w5kAdDaQj via @YouTube

May 12, 2020 View post →
Mondal Music
@bdviolinist · X

RT @banglamusichd: করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/ta62hFm9s4 via @YouTube

May 10, 2020 · 1 share · 68 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/ZXpeKl60Nt via @YouTube

May 8, 2020 · 8 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/rFfc5MCyQG via @YouTube

May 8, 2020 · 8 followers View post →
Graham Dellaire @docdellaire.bsky.social
@DocDellaire · X

@akelvinlab Pretty relevant paper here in thinking about COVID19 and your cardiovascular health... ACE2 and atherosclerosis. https://t.co/138g8faALD

May 5, 2020 · 2,664 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/ta62hFm9s4 via @YouTube

May 5, 2020 · 1 share · 8 followers View post →
Bangla Music HD
@banglamusichd · X

https://t.co/NQmfte2jcE

May 5, 2020 · 8 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/NQmfte2jcE via @YouTube

May 5, 2020 · 8 followers View post →
Bangla Music HD
@banglamusichd · X

https://t.co/NQmftejUBe

May 4, 2020 · 8 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/CPkVwNGqCr via @YouTube

May 4, 2020 · 8 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/CPkVwNoPdR via @YouTube

May 4, 2020 · 8 followers View post →
sofiullahdhali9@gmail.com
@sofiullahdhali9 · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/uT9iSiULgJ via @YouTube

May 1, 2020 · 1 followers View post →
Bangla Music HD
@banglamusichd · X

করোনাভাইরাস (COVID-19) এর সর্বশেষ পরিস্থিতি https://t.co/NNVB6OOKN5 via @YouTube

Apr 30, 2020 · 8 followers View post →
aula【大規模PCR検査保護隔離治療支援を最優先に。ゼロコロナ志向で一刻も早く一人でも多く助けて】
@aula531 · X

RT @zzz_as_zzz: 活性酸素には、一時騒がれていたフリーラジカルとかも含まれ、色々な病気の症状に関係しているわけです。 https://t.co/oNYcd8Ve6X ACE2は、血管内皮を守るんですよ、という論文。 https://t.co/7ZfiQnQVp…

Apr 30, 2020 · 1 share · 1,209 followers View post →
A_S(ヤドカリ:釣り餌にしないで下さい)
@zzz_as_zzz · X

活性酸素には、一時騒がれていたフリーラジカルとかも含まれ、色々な病気の症状に関係しているわけです。 https://t.co/oNYcd8Ve6X ACE2は、血管内皮を守るんですよ、という論文。 https://t.co/7ZfiQnQVpy Oxydative stress https://t.co/OqmTRj7jmU

Apr 30, 2020 · 1 share · 872 followers View post →
Tom Poole
@TomPoole007 · X

#oxidativestress https://t.co/snpGVmMQYC #Ace2 #ace2receptor #a779 #ros #angiotensin #SARSCoV2 #hadph #diabetes #obesity #angiotensin17 #endothelium

Apr 29, 2020 · 1 like · 1,780 followers View post →
Democracy, Love, Peace, ClimateEmergncy, FBPPR
@KatharineJStin2 · X

RT @JSegor: COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 28, 2020 · 2 shares · 2,905 followers View post →
#FBPE #Brexit is a coup #Independence4OurNations
@EUnotCoup · X

RT @JSegor: COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 28, 2020 · 2 shares · 6,695 followers View post →
Jeff Segor
@JSegor · X

COVID-19 attacks ACE2, which can be really bad. Here's why: https://t.co/PsUYyHeBl6 https://t.co/nzqy9Ay1Z7

Apr 27, 2020 · 2 likes · 2 shares · 753 followers View post →
Tom Poole
@TomPoole007 · X

https://t.co/NzUtTJLtdj #thrombosis #COVID19 #blood #clot

Apr 27, 2020 · 1,780 followers View post →
Alexander Dreyzen
@ADreyzen · X

Does cov2, by taking out (binding to) ACE2 enzyme, impairs endothelium-dependent relaxation? Is this where the lack of NO and vit D confounds the outcomes, by also boosting the clotting factors? https://t.co/LQSv3czD5J

Apr 27, 2020 · 603 followers View post →
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