PubHawk
Cancer January 2010 PMID 20014183

A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL).

Elena J Ladas, David J Kroll, Nicholas H Oberlies, Bin Cheng, Deborah H Ndao, Susan R Rheingold, Kara M Kelly

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Mentions

33
Peak: 1 in May 2022
across 5 sources since May 2022

Extended reach

10,651
potential audience

Total likes

100

Video views

4,847

Mentions per month

May 2022 – Dec 2023

Where it's discussed

  • Facebook20 posts
  • News6 articles
  • Blogs3 articles
  • X / Twitter2 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate moderate interest by referencing the safety and potential benefits of milk thistle, with comments like 'credible beneficial effects' and suggesting consultation with herbalists, indicating a curious yet cautious attitude toward integrating herbal remedies with medical treatment.

AgreementModerate agreement

The posts acknowledge the potential benefits of milk thistle, aligning with the study's cautious optimism about its safety and possible efficacy.

InterestModerate interest

Discussions show some curiosity about herbal remedies and their application in pediatric leukemia, but the engagement remains moderate.

EngagementModerate engagement

Posts reflect thoughtful consideration, mentioning consulting herbalists and doctors and discussing the credibility of the findings.

ImpactNeutral impact

While the conversations recognize the study's relevance, they do not express overwhelming excitement or a call to change practice immediately.

Abstract in brief

  • This study explored the use of milk thistle (MT) to treat liver toxicity in children with acute lymphoblastic leukemia (ALL), finding that MT was safe and showed a trend towards reducing liver enzyme levels, although no significant differences in liver function were observed after 28 and 56 days.
  • In laboratory tests, MT did not interfere with chemotherapy drugs like vincristine and asparaginase and even showed a modest synergistic effect with vincristine, suggesting it may enhance some treatment aspects without compromising chemotherapy efficacy.
  • Overall, while results indicate MT could help reduce liver toxicity in children undergoing leukemia treatment, further research is necessary to determine optimal dosing, treatment duration, and long-term impacts on leukemia outcomes.
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Top posts

Most liked on X and Bluesky
John
@TrueLibertyX · X

@jonathanstea @DrLizaMD @PharmacistScott Milk thistle seems to have credible beneficial effects on liver function, whether healthy individuals benefit from it may be unproven but it’s not an irrational conclusion. https://t.co/2cfQxcOHHh

Jun 23, 2023 · 7 likes · 157 followers View post →
mauricev
@mauricev · X

@clarewenham In the herbal world, milk thistle is used to protect the liver. I would get the advice of an herbalist regarding treating someone so young and discuss it with the doctors, but it has been tested in some children https://t.co/f6plFKFsrR

May 10, 2022 · 5,648 followers View post →

All mentions

John
@TrueLibertyX · X

@jonathanstea @DrLizaMD @PharmacistScott Milk thistle seems to have credible beneficial effects on liver function, whether healthy individuals benefit from it may be unproven but it’s not an irrational conclusion. https://t.co/2cfQxcOHHh

Jun 23, 2023 · 7 likes · 157 followers View post →
mauricev
@mauricev · X

@clarewenham In the herbal world, milk thistle is used to protect the liver. I would get the advice of an herbalist regarding treating someone so young and discuss it with the doctors, but it has been tested in some children https://t.co/f6plFKFsrR

May 10, 2022 · 5,648 followers View post →