Single vs. multiple sets of resistance exercise for muscle hypertrophy: a meta-analysis.
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Oct 2013 – Sep 2025Where it's discussed
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The group collectively emphasizes that 2-3 sets are sufficient for muscle growth, with several posts quoting the meta-analysis figures like 40% more hypertrophy for multiple sets, and dismissing longer sessions or higher volumes as inefficient. The tone combines scientific references with practical advice, highlighting the potential to optimize gym routines based on research, which underscores the high engagement and perceived impact of the publication's findings.
Most discussions support the article's conclusion that doing 2-3 sets per exercise results in significant muscle growth, with some dismissing higher volumes as unnecessary.
Posts demonstrate high engagement with the topic, referencing specific research findings and debating ideal training volumes.
Posts go beyond surface-level comments, citing studies, discussing practical training advice, and weighing the significance of the meta-analysis.
The discussions suggest the findings could influence training routines, emphasizing effective volume for muscle hypertrophy and encouraging readers to optimize their workout strategies.
Abstract in brief
- The meta-analysis found that doing multiple sets of resistance exercises leads to greater muscle growth (hypertrophy) compared to doing just one set, with the difference being statistically significant.
- There is a trend suggesting that performing around 2-3 sets per exercise may be more effective for muscle hypertrophy than doing only one, and adding more sets (like 4-6) might further increase muscle growth, although the difference between 2 and 4-6 sets isn't significant.
- Overall, multiple sets (especially more than one) are linked to about 40% greater muscle growth than doing a single set, applicable to both trained and untrained individuals.]
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Most liked on X and BlueskyYou will build more muscle with more lifting sets, but only up to a point. This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets didn't add anything significant over 2-3 sets. https://t.co/lOR3j5gvp8
This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. Pick 1 exercise per muscle group, do 2-3 hard sets with good form & get out. https://t.co/lOR3j5gvp8
This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2-3 sets. The takeaway from this is that 3 hard sets per muscle group per session is enough for most people to see results. https://t.co/lOR3j5gvp8
This meta-analysis of hypertrophy studies found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. The takeaway from this? Pick 1 exercise per muscle group, do 2-3 hard sets and get out. https://t.co/lOR3j5gvp8
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
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@Mangan150 @greenlandsharky Yes it seems that 1 set to failure accomplishes 60% of muscle growth, that would be the lazy person variant and still useful https://t.co/oXAgc5w791
RT @DanielBerglind:
RT @DanielBerglind:
Multiple sets are associated with 40% greater muscle growth. 60% of muscle growth is associated with just 1 set per exercise. The average person should just focus on 1-2 sets of muscle specific exercises, X2 per week. https://t.co/XFQu9B8M23
RT @DanielBerglind:
This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. https://t.co/JeNyahNgBt
This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. https://t.co/JeNyahNgBt
"0.24 for 1 set, 0.34 for 2-3 sets, and 0.44 for 4-6 sets" https://t.co/BgBgXye1u3 Why would anyone do over 1 set in the gym? It's not value at all.
Here's a study showing that 2-3 sets adds about 40% more stimulus for building muscle than a single set. It also found that but 4-6 sets does not add anything significant over 2-3 sets. (this was a meta analysis of 8 studies) https://t.co/lOR3j5gvp8
This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. https://t.co/lOR3j5gvp8
This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. https://t.co/lOR3j5gvp8
RT @Rob_NBF: You don't need long sessions hammering a single muscle group over and over. Research shows 2-3 sets yield around 40% more gr…
You don't need long sessions hammering a single muscle group over and over. Research shows 2-3 sets yield around 40% more growth than one set, but 4-6 sets doesn't add much more. https://t.co/lOR3j5gvp8
If you’re interested in the exact research studies mentioned above - 1. https://t.co/DIXnmrcZe6 2. https://t.co/uzoX2Vfnsh 3. https://t.co/0l3WTXVy4G
2. Less is more. 20 sets of chest on "chest day" isn't necessarily better than 10, or 5 sets. This study found that 4-6 sets to failure made no significant difference to hypertrophy when compared with 2-3 sets to failure. https://t.co/lOR3j5gvp8
Wondering how many sets you should do in a workout? Research shows a positive relationship between training volume and muscle growth. More sets can lead to around 80-85% more gains compared to just one set. https://t.co/DIXnmrcZe6
This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2-3 sets. The takeaway from this is that 3 hard sets per muscle group per session is enough for most people to see results. https://t.co/lOR3j5gvp8
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl8Kh3
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
RT @Rob_NBF: This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant o…
RT @Rob_NBF: This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant o…
RT @Rob_NBF: This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant o…
RT @Rob_NBF: This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant o…
RT @Rob_NBF: This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant o…
This meta-analysis found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. Pick 1 exercise per muscle group, do 2-3 hard sets with good form & get out. https://t.co/lOR3j5gvp8
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
@nutrient_dens Just look at any study where they compare 1 set to 2-3 to 5-6 etc more sets + more hypertrophy, but diminishing returns. Here is a meta where 1 set looks like its in the 60s with 2sets close to 80, I don't think this is failure sets, but don't have https://t.co/mdVxIYY9uR
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This meta-analysis of hypertrophy studies found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add…
RT @Rob_NBF: This meta-analysis of hypertrophy studies found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add…
This meta-analysis of hypertrophy studies found that 2-3 sets adds about 40% more than a single set, but 4-6 sets does not add anything significant over 2-3 sets. The takeaway from this? Pick 1 exercise per muscle group, do 2-3 hard sets and get out. https://t.co/lOR3j5gvp8
This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2-3 sets. The takeaway from this is that 3 hard sets per muscle group per session is enough for most people to see results. https://t.co/lOR3j5gvp8
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUl9i6B
RT @Rob_NBF: You will build more muscle with more lifting sets, but only up to a point. This study found that 2-3 sets resulted in more hy…
RT @Rob_NBF: You will build more muscle with more lifting sets, but only up to a point. This study found that 2-3 sets resulted in more hy…
Overtraining a muscle is not the way forward. 2 to 3 sets were proven to stimulate more muscle growth than 1set and multiple sets. https://t.co/oYYUhXofoR
You will build more muscle with more lifting sets, but only up to a point. This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets didn't add anything significant over 2-3 sets. https://t.co/lOR3j5gvp8
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
RT @musclearuaru: 【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? h…
【効果的なセット数は◯セット?】 この分析では1種目につき「4~6セット」がベストとの事 確かラットでの実験で「6セットは3セットの時より筋肥大したが、9セット行うと効果は減少」という研究もあったので【6セット前後】の所に良い量がある? https://t.co/yDbUUlql8B
This meta-analysis confirms that excessive volume isn’t necessary. https://t.co/apN3YGAxEN Just make sure that you’re training to failure or near failure with proper form. (We can have a different conversation if you’re strength training for a powerlifting competition)
RT @Rob_NBF: This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2…
RT @Rob_NBF: This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2…
This study found that 2-3 sets resulted in more hypertrophy than 1 set, but 4-6 sets did not result in more hypertrophy than 2-3 sets. The takeaway from this is that 3 hard sets per muscle group per session is enough for most people to see results. https://t.co/lOR3j5gvp8
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
RT @Rob_NBF: This study was a robust meta-analysis of lots of studies on the hypertrophy response to multiple sets. It found that 2-3 sets…
Now while 4-6 x 10 might be time consuming it’s is optimal, the time poor can make do with 2-3 sets https://t.co/TcZTAXoqH4
RT @cjexercise: After last weeks look at warming up lets get back to looking at how to grow some muscles. Click the link to read a Meta-An…
After last weeks look at warming up lets get back to looking at how to grow some muscles. Click the link to read a Meta-Analysis about Single vs. Multiple Sets of Resistance Exercise for Muscle Hypertrophy https://t.co/YDSDgzzSj3 https://t.co/na1By3mOL6
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